Eagle LogoPEPTIDE INITIATIVE

Peptide Database

Goals
Fat LossMuscle BuildingInjury HealingAnti-AgingCognitive EnhancementSleep OptimizationImmune SupportGut HealingSkin RejuvenationSexual Health
Peptides
Adipotide
Weight Management
AOD-9604
Weight Management
BPC-157
Healing & Recovery
Cagrilintide
Weight Management
CJC-1295
Growth Hormone
DSIP
Sleep & Recovery
Epithalon
Anti-Aging
GHK-Cu
Anti-Aging
GHRP-2
Growth Hormone
HCG
Hormone Support
Hexarelin
Growth Hormone
HGH
Growth Hormone
IGF-1 LR3
Growth Hormone
Kisspeptin
Hormone Support
Melanotan-2
Cosmetic
MOTS-C
Metabolic
NAD+
Anti-Aging
Oxytocin Acetate
Hormone Support
PEG-MGF
Recovery
PNC-27
Cancer Research
PT-141
Sexual Health
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Snap-8
Cosmetic
SS-31
Mitochondrial
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Thymosin Alpha-1
Immune
Tirzepatide
Weight Management
Total Peptides: 32
Back to Home
Eagle LogoPEPTIDE INITIATIVE

Peptide Database

Goals
Peptides
Adipotide
Weight Management
AOD-9604
Weight Management
BPC-157
Healing & Recovery
Cagrilintide
Weight Management
CJC-1295
Growth Hormone
DSIP
Sleep & Recovery
Epithalon
Anti-Aging
GHK-Cu
Anti-Aging
GHRP-2
Growth Hormone
HCG
Hormone Support
Hexarelin
Growth Hormone
HGH
Growth Hormone
IGF-1 LR3
Growth Hormone
Kisspeptin
Hormone Support
Melanotan-2
Cosmetic
MOTS-C
Metabolic
NAD+
Anti-Aging
Oxytocin Acetate
Hormone Support
PEG-MGF
Recovery
PNC-27
Cancer Research
PT-141
Sexual Health
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Snap-8
Cosmetic
SS-31
Mitochondrial
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Thymosin Alpha-1
Immune
Tirzepatide
Weight Management
Total Peptides: 32
Back to Home

Peptide History

Stories of
Scientific Triumph

Explore the dramatic journeys behind the peptides that are reshaping medicine and inspiring the next generation of researchers.

1926

Serelaxin (Recombinant Human Relaxin-2)

From pregnancy hormone to heart failure hope

Clinical development discontinued
1928

Nisin A Lantibiotic Bacteriocin

A bacteria-made protein from cheese that kills superbugs without creating resistance.

FDA Approved (Food Preservative) / Medical Research
1931

Substance P Receptor Blockers (Neurokinin-1 Antagonists)

From 1931 mystery signal to 2003 FDA-approved migraine and nausea fighter

FDA approved - widely used in hospitals
1939

Gramicidin D (Linear Gramicidin)

The soil antibiotic that punched holes in bacteria—and changed medicine forever.

FDA Approved (Topical)
1947

Polymyxin B Sulfate

The abandoned antibiotic that became the last hope against superbugs

FDA Approved
1949

Cerebrolysin (FPF-1070)

A porcine brain extract that regenerates damaged neurons and restores cognitive function across 50+ countries.

Approved in 50+ countries; extensively used clinically worldwide
1956

Human Growth Hormone

From Pituitary Extracts to Genetic Engineering: A Revolution in Medicine

FDA Approved & Widely Used
1965

Enalapril Maleate (Vasotec)

Snake venom becomes life-saving medicine

FDA approved, widely prescribed
1966

Thymosin Beta-4 (Tβ4)

The body's secret healing signal hidden in nearly every cell

Phase 3 Clinical Trials (Eye Disease); Preclinical to Phase 2 (Heart Disease)
1966

Thymosin Beta-4

The Body's Master Healer — From Horse Racing Scandal to Medical Marvel

Research / WADA Prohibited
1966

Thymopoietin

A 49-amino-acid immune hormone that bridges thymic and neuromuscular systems.

Active Research & Clinical Use
1969

Lentinan (β-1,3-D-glucan from Lentinula edodes)

From ancient mushrooms to modern cancer immunotherapy

Approved in Japan & China (Not FDA-approved)
1970

Ziconotide (Prialt)

Snake venom transformed into a powerful pain reliever that doesn't addict you.

FDA approved for severe chronic pain (2004)
1970

Vasoactive Intestinal Peptide

A 28-piece messenger that tells blood vessels and lungs to relax and heal

In clinical use in some countries; undergoing trials in the United States
1971

Gonadotropin-Releasing Hormone (GnRH)

The master remote control for your reproductive system—a tiny molecule that controls fertility, puberty, and hormones throughout your life.

FDA approved for fertility testing and treatment
1973

Palmitoyl Tripeptide-1

Three tiny amino acids that unlock your skin's natural repair system

Cosmetic Use
1973

Glycyl-Histidyl-Lysine Copper (GHK-Cu)

The healing peptide that turns back time in wounds and skin

Active research and cosmetic use
1974

Thymalin

A polypeptide complex extracted from calf thymus that activates immune function and extends lifespan.

Approved Pharmaceutical (Russia)
1975

Thymopentin (TP-5)

A synthetic pentapeptide immunomodulator derived from thymopoietin that contains just five amino acids but retains all the immune-boosting power of the full 49-amino-acid hormone.

FDA investigational; approved in Italy, China, and other countries
1976

Bestatin (Ubenimex)

The Japanese enzyme inhibitor that unlocked immune restoration in cancer therapy

Approved in Japan (Not FDA-approved)
1977

Thymulin (FTS)

A nine-amino-acid zinc-dependent peptide hormone produced exclusively by thymic epithelial cells that orchestrates T-cell differentiation and immune function.

Advanced Gene Therapy Clinical Development
1979

PAT (Peptide Analog of Thymulin)

A modified hormone that fights inflammation and pain without needing a rare mineral.

Research phase - Animal and early human trials ongoing
1980

Sermorelin Acetate (Geref)

The Natural Approach — Telling Your Body to Make Its Own Growth Hormone

FDA Withdrawn (Commercial, not Safety)
1980

Testagen (KEDG Tetrapeptide) - Testicular Bioregulator

Soviet Military Science Meets Male Reproductive Health - The Testicular Peptide That Normalizes Testosterone Production

Research
1980

Glu-Asp-Leu Tripeptide Bioregulator (EDL)

Liver-Derived Peptide Bioregulator for Hepatoprotection and Digestive System Regulation

Research
1980

Immunoxel (Dzherelo)

A Ukrainian botanical powerhouse that awakened dormant immune defenses against tuberculosis and HIV.

Approved immunomodulator in Ukraine; adjunctive TB/HIV therapy
1981

Atrial Natriuretic Peptide

The hormone that proved the heart makes chemicals.

FDA approved diagnostic marker and approved treatment in Japan
1981

Fertirelin Acetate

The peptide that helped feed billions by making cattle fertile

Approved in Japan 1981, used in veterinary medicine globally
1982

N-Acetyl Semax Amidate (Acetylated Semax with Amidate Modification)

From Soviet neuroscience laboratories to advanced neuroprotection: the engineered peptide that enhances the original ACTH analog

Approved nootropic/neuroprotective drug in Russia; Active research in neuroregenerative medicine and cognitive enhancement
1982

Buserelin Acetate

The first GnRH agonist that taught doctors how to turn off hormone signals to fight cancer and help couples have babies

Approved and widely used
1982

Growth Hormone Releasing Hormone Fragment 1-29 (Sermorelin Acetate / Geref)

The brain's forgotten hormone that sparked a Nobel Prize feud and changed how we treat growth disorders.

Available through compounding pharmacies; Tesamorelin (stabilized analog) FDA-approved for HIV lipodystrophy
1982

Triptorelin (Decapeptyl/Trelstar)

A smarter gonadorelin that tricks your body into medical castration—now your most powerful weapon against prostate cancer, endometriosis, and early puberty.

FDA approved for prostate cancer, endometriosis, precocious puberty, and IVF
1983

Liraglutide (Victoza / Saxenda)

The Anglerfish Discovery That Launched the Weight-Loss Revolution

FDA Approved
1984

Growth Hormone Releasing Peptide-6 (His-D-Trp-Ala-Trp-D-Phe-Lys-NH2)

The tiny lab-made molecule that tricked the body into growing — and accidentally led scientists to a hidden hunger hormone in the stomach.

Research Compound
1984

3-L-pyroglutamyl-L-thiazolidine-4-carboxylic acid

The immune system's gentle wake-up call from Italy

Approved in 20+ countries, used clinically but not FDA approved in the USA
1985

Leuprolide Acetate

The first GnRH drug that gave hope to cancer patients in 1985

FDA approved for multiple indications; widely used globally
1986

Cortexin (Brain-Derived Neuropeptide Complex)

Russian brain rescue peptides that cross the blood-brain barrier to restore neural function.

Approved and in clinical use in Russia and CIS countries since 1999
1987

Daptomycin (Cubicin)

The antibiotic Eli Lilly threw away—rescued by one determined doctor.

FDA Approved
1987

Pramlintide (Symlin)

The Missing Half of Insulin's Story

FDA Approved
1987

Magainin-2 Antimicrobial Peptide

The Frog Skin Shield That Launched a Revolution

Research / Preclinical
1988

Angiotensin II Fragment (1-7)

The blood pressure lowering peptide that changes how we treat heart disease

Clinical Research
1988

Nesiritide (Natrecor, Recombinant B-Type Natriuretic Peptide)

The heart's own healing signal, recreated in the lab to help failing hearts.

FDA approved, 2001. Used for acute heart failure in hospitals.
1988

Ularitide (Synthetic Urodilatin, ANP Analog)

The kidney's own healing protein, made in a lab to rescue failing hearts.

Investigational in Phase 3 trials. Not yet FDA approved as of 2025.
1989

Pituitary Adenylate Cyclase-Activating Polypeptide-38

The brain's emergency repair signal discovered in 1989

Research phase - clinical trials underway
1989

Ventfort (Vascular Peptide Bioregulator)

The Vascular Wall Restorer - Engineered for Cardiovascular Resilience

Research
1990

CRYSTAGEN (Thr-Lys-Asp Tripeptide)

Synthetic thymus-derived immunomodulator for T-cell normalization and immune system regeneration

Research
1990

N-Acetyl Selank Heptapeptide

Russia's first psychotropic peptide drug designed to calm anxiety and sharpen the mind without sedation.

Approved in Russia as pharmaceutical; investigational elsewhere
1990

Palmitoyl Hexapeptide (Biopeptide EL, Pal-VGVAPG)

The chemical messenger that tells your skin to stay young and firm

Widely used in cosmetic products and ongoing research
1990

PROSTAMAX (Lys-Glu-Asp-Pro, KEDP Tetrapeptide Bioregulator)

Cellular Restoration for Prostate Health - A Khavinson Peptide Bioregulator

Research
1990

Nafarelin Acetate

The breakthrough spray that made hormone therapy easier to take

FDA approved and widely used for endometriosis and precocious puberty
1990

Vilon (Lys-Glu Dipeptide)

The Shortest Bioregulator - Engineering Immunity with Two Amino Acids

Research
1991

Pralmorelin Hydrochloride (GHRP Kaken 100)

The Most Potent Growth Hormone Releaser That Never Got Its Moment

Approved in Japan only as a diagnostic agent since 2004
1991

N-phenylacetyl-L-prolylglycine ethyl ester (GVS-111, Omberacetam)

A thousand-fold cognitive leap: The remarkable story of Russia's most potent nootropic peptidomimetic

Approved in Russia and several post-Soviet countries as a nootropic pharmaceutical; Unapproved New Drug status in the United States
1991

Imunofan (Arginyl-alpha-aspartyl-lysyl-valyl-tyrosyl-arginine)

Russia's Six-Amino-Acid Shield Against Immune Collapse

Approved in Russia and CIS countries; not FDA-approved; available as injection, nasal spray, and rectal suppositories
1992

Xenin-25 (Xenin peptide hormone)

The appetite control peptide that helps manage blood sugar

Preclinical and early clinical research; exploring potential diabetes applications
1992

Lactoferricin B

Nature's Antibiotic Hidden in Mother's Milk

Research
1992

Examorelin / Hexarelin (His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2)

The heart drug that never was—a growth hormone peptide that saved failing hearts, then disappeared.

Discontinued — Phase II (Clinical Development Halted)
1992

Insulin-like Growth Factor 1 Long R3

The Enhanced Growth Factor Revolution

Research Chemical / Industry Standard
1992

Exenatide (Byetta / Bydureon)

The Lizard Venom That Launched a Diabetes Revolution

FDA Approved
1993

Pentadecapeptide BPC-157 (Body Protection Compound)

The healing peptide that fixes damaged tissue from the inside

Preclinical and clinical research ongoing; not yet FDA approved
1993

Adrenomedullin (AM)

The most powerful blood vessel relaxer your body can make.

Phase 2-3 clinical trials for sepsis and acute heart failure; investigational drug
1994

Chonluten (Respiratory Tract Bioregulator Peptide)

Restoring the Breath: A Peptide Revolution in Respiratory Medicine

Research
1994

Pancragen (Lys-Glu-Asp-Trp Tetrapeptide)

The Soviet-Era Pancreatic Bioregulator That Bridges Gerontology and Metabolic Health

Research
1995

Tripeptide-29 (Glycine-Proline-Hydroxyproline Collagen Fragment)

The collagen fragment that tells your skin to repair and rebuild itself

Active ingredient in anti-aging cosmetics (non-prescription)
1995

Cathelicidin Antimicrobial Peptide Family

Ancient immune warriors living in every animal's white blood cells.

Clinical Trials
1995

Urocortin (Stress-Response Peptide Family)

The stress hormone that secretly protects your heart

Advanced research - clinical trials for heart failure treatment completed with promising results
1995

Vesilute (Lys-Glu-Asp Tripeptide Bioregulator)

Restoring Bladder and Urogenital System Function Through Peptide Bioregulation

Research
1995

Cetrorelix Acetate

The game-changing antagonist that stops the hormone surge instantly instead of causing a dangerous flare

FDA-approved and standard in IVF clinics globally
1995

Cathelicidin Antimicrobial Peptide LL-37

Your Body's Built-In Antibiotic That Superbugs Can't Outsmart

Research / Clinical Trials
1995

Tesamorelin Acetate (EGRIFTA)

The Canadian Peptide That Gave HIV Patients Their Bodies Back

FDA Approved (2010)
1997

Human Beta-Defensin 2

The Skin's Secret Antibiotic Hidden in Plain Sight

Research
1997

MK-677 (Ibutamoren Mesylate / L-163,191)

The Pill That Acts Like a Peptide

Phase 2 clinical trials (LUM-201 by Lumos Pharma for children with growth hormone deficiency)
1998

Tabimorelin (NN703)

The Danish pill that almost beat the peptide

Discontinued—never reached patients
1998

Apelin Peptide 13-Amino Acid Form

The heart-strengthening peptide discovered in cow stomachs that could revolutionize heart failure treatment

Advanced Research and Early Clinical Trials
1998

Livagen (KEDA Tetrapeptide - Lys-Glu-Asp-Ala)

A liver-derived bioregulator that restores hepatocyte function and awakens silent genes through epigenetic innovation

Research
1999

CARTALAX (Ala-Glu-Asp Tripeptide Bioregulator)

Cartilage's molecular messenger: Khavinson's synthetic bioregulator for musculoskeletal regeneration

Research
1999

Ganirelix Acetate

The hormone brake for baby-making breakthroughs

FDA approved 1999, widely used in fertility clinics
1999

Acetyl Hexapeptide-3 (Ac-EEMQRR), Marketed as Argireline

The wrinkle fighter that puts the brakes on facial muscles

One of the world's best-selling cosmetic peptides
1999

CP-424,391: The Growth Hormone Pill That Chose Veterinary Medicine

A tiny molecule that makes hungry animals hungry again

FDA-approved for veterinary use (dogs and cats)
2000

Palmitoyl Pentapeptide-4

The wrinkle fighter that teaches old skin to act young again

Cosmetic Use
2000

PNC-27: The Cancer Cell Assassin

The peptide that selectively destroys cancer cells while leaving healthy cells unharmed

Preclinical - IND Filing Expected 2025
2000

EDR Peptide (Glu-Asp-Arg)

The Three-Amino-Acid Shield That Protects the Aging Brain

Research Compound
2000

Ala-His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2

One amino acid changed everything. How adding a single building block revealed the hidden complexity of growth hormone signals.

Research Compound
2001

SM-130686 (6-Carbamoyl-3-(2-chlorophenyl)-1-(2-diethylaminoethyl)-4-trifluoromethyloxindole hydrochloride)

The Oxindole That Could Have Been — A Ghost from the Chemical Library

Discontinued (Research Tool Only)
2001

Human Beta-Defensin 3

The Swiss Army knife of immune defense—a tiny soldier that attacks both types of dangerous bacteria.

Research
2001

Lys-Pro-Val (Alpha-MSH Fragment)

A tiny piece of nature's anti-inflammatory switch found in hormones

In preclinical research and early clinical trials for IBD
2001

SYN-AKE (Dipeptide Diaminobutyroyl Benzylamide Diacetate)

The snake venom secret that freezes wrinkles without injections

Commercially available and widely used
2003

Lixisenatide (Adlyxin / Lyxumia)

The Mealtime Guardian Built From Lizard DNA

FDA Approved
2003

Larazotide Acetate (AT-1001)

The peptide that seals the gut and treats celiac disease from the inside.

Phase 3 Clinical Trials
2003

Abarelix (Plenaxis)

The pioneer that opened a door, then closed it again

FDA approved but withdrawn from U.S. market; available in Europe through restricted programs
2003

Leuphasyl Peptide Solution

The natural wrinkle fighter that works like your body's own pain relief

Commercially available
2003

Cerluten (Brain-derived Peptide Bioregulator Complex)

Restoring the Brain's Natural Language: A Russian Peptide's Journey from Laboratory to Clinical Practice

Research
2003

Palmitoyl Tetrapeptide-7 (Pal-GQPR), Marketed as Rigin

The skin calmer that stops inflammation before it starts

Widely used in premium anti-aging skincare products
2004

Szeto-Schiller Peptide 31 (Elamipretide)

The Accidental Discovery That Rescued Dying Mitochondria

FDA Approved (2025)
2004

Intermedin (Adrenomedullin-2)

The newly discovered peptide protecting hearts and blood vessels

Research phase - exploring for heart failure, kidney injury, and sepsis treatment
2005

Myristoyl Pentapeptide-17 (N-Myristoyl Penta-Amino Acid Complex)

The peptide that tells your eyelashes to grow stronger and thicker

Active ingredient in cosmetics (non-prescription)
2005

Acetyl Octapeptide-3 (SNAP-8)

Botox in a Bottle — The Peptide That Relaxes Wrinkles Without Needles

Cosmetic Ingredient
2005

Dulaglutide (Trulicity)

The Antibody Shield That Made Once-a-Week Possible

FDA Approved
2006

Setmelanotide (Imcivree)

The Drug That Finally Fixed the Broken Hunger Switch

FDA Approved
2008

ARA-290 (Cibinetide)

The healing peptide that reduces pain and protects nerves without the side effects of traditional EPO.

Clinical Trials for Multiple Conditions
2008

Degarelix Acetate (Firmagon)

The hormone blocker that stops cancer without the dangerous spike

FDA approved and widely used for advanced prostate cancer
2010

P21 (P021; Ac-DGGLAG-NH2)

A Brain-Healing Peptide Born from Love and Neuroscience

Preclinical / Research Stage
2012

Dihexa (PNB-0408; N-hexanoic-Tyr-Ile-(6) aminohexanoic amide)

A tiny peptide that rewires the brain by binding hepatocyte growth factor with extreme precision.

Preclinical / Research Stage
2015

Orforglipron (LY3502970)

The Pill That Could Change Everything: A Small Molecule Revolution

Phase 3 Clinical Trials
2017

Survodutide (BI 456906)

The Dual-Power Drug That Breaks the Glucagon Taboo

Phase 3 Clinical Trials
2017

Macimorelin Acetate (Macrilen®/Ghryvelin®)

The Simple Drink That Replaced a Dangerous Test

FDA Approved (December 2017) - First and only oral diagnostic for adult growth hormone deficiency
2018

Mazdutide (IBI362)

The Chinese Biotech That Beat The World to a New Drug Class

Approved (China)
2019

Pemvidutide (ALT-801)

The Dual-Action Breakthrough That Tackles Fatty Liver and Addiction

Phase 2b Clinical Trials