How It Works
Peptide
Mechanism
Thymic peptides work by stimulating thymic epithelial cells to produce thymulin, activating the differentiation of hematopoietic stem cells into mature CD28+ T lymphocytes. Thymosin Alpha-1 specifically modulates dendritic cell function and mitigates cytokine storm responses by regulating CD8+ T-cell activation. LL-37 provides direct antimicrobial activity while recruiting adaptive immune cells to infection sites.
The thymus gland undergoes progressive involution with age, reducing naïve T-cell output by approximately 3% per year after puberty. By age 65, thymic output is reduced by 95%. Thymic peptides bypass this decline by directly stimulating T-cell maturation pathways, essentially 'resetting' immune age.