PEG-MGF
Pegylated Mechano Growth Factor
PEG-MGF is a pegylated variant of Mechano Growth Factor, an engineered form of IGF-1 designed for enhanced stability and prolonged action. The pegylation process extends the half-life from minutes to days, making it highly effective for muscle fiber hyperplasia, satellite cell activation, and accelerated muscle tissue repair. Unlike standard IGF-1, PEG-MGF specifically targets muscle-specific growth pathways with reduced systemic effects.
PEG-MGF Dosing Guide
Primary Benefits
- Enhanced muscle fiber hyperplasia (new fiber formation)
- Accelerated muscle tissue repair and recovery
- Increased satellite cell activation and proliferation
- Extended half-life through pegylation technology
- Superior muscle protein synthesis rates
How It Works
PEG-MGF functions as a localized muscle growth factor that activates satellite cells through IGF-1 receptor binding. The pegylation process extends the compound's half-life from 5-7 minutes (native MGF) to 24-72 hours, allowing sustained anabolic signaling. It specifically promotes muscle fiber hyperplasia (formation of new muscle fibers) rather than just hypertrophy, leading to more permanent muscle gains. The compound activates the PI3K/Akt/mTOR pathway, enhancing protein synthesis while reducing protein breakdown.
Quick Reference
Typical Dosage Range
Initial dosing begins at 100 mcg daily for 1-2 weeks to assess tolerance. Most research protocols use 200-300 mcg daily as the therapeutic dose, with advanced users utilizing up to 400 mcg daily. Timing is crucial - post-workout administration (within 30 minutes) maximizes muscle activation, while pre-sleep dosing takes advantage of natural growth hormone release. Cycles typically run 8-16 weeks with 4-week breaks.
Administration Methods
Subcutaneous injection using insulin syringes (29-31 gauge, 0.5-1 inch) into areas with sufficient subcutaneous fat. Common sites include abdominal area (2 inches from navel), anterior thigh, or deltoid region. Rotate injection sites to prevent tissue damage or lipodystrophy. Reconstitution requires bacteriostatic water, typically 1-2ml per vial. Store reconstituted solution refrigerated and use within 14 days.
Medical Disclaimer
PEG-MGF is a research chemical not approved by the FDA for human use. This information is for educational purposes only and should not replace consultation with healthcare providers. Individual results may vary significantly. Research use only - not intended for human consumption or therapeutic application.