GHRP-2
Growth Hormone Releasing Peptide-2
GHRP-2 (Growth Hormone Releasing Peptide-2), also known as pralmorelin, is a synthetic hexapeptide that acts as a potent agonist at the ghrelin/growth hormone secretagogue receptor (GHS-R). It triggers pulsatile growth hormone release from the pituitary gland, mimicking the body's natural GH secretion patterns. GHRP-2 was developed as a diagnostic agent and is clinically approved in Japan for assessing growth hormone deficiency. Unlike direct GH administration, GHRP-2 works through the body's natural pathways, making it a preferred option for those seeking to enhance their natural growth hormone production safely and effectively.
GHRP-2 Dosing Guide
Primary Benefits
- Stimulates natural GH release
- Enhances muscle growth and recovery
- Improves body composition
- Supports fat loss
- Enhances sleep quality
How It Works
GHRP-2 works through specific biological pathways to deliver therapeutic benefits.
What It's Used For
GHRP-2 is a growth hormone-releasing peptide that stimulates natural growth hormone production in the body. It works by binding to ghrelin receptors and triggering pulsatile GH release from the pituitary gland.
Muscle Growth & Strength
Increases lean muscle mass and improves strength gains from training.
Fat Loss
Enhances fat metabolism and improves body composition.
Recovery & Healing
Speeds up recovery from workouts and injuries by boosting GH and IGF-1 levels.
Anti-Aging Benefits
Improves skin elasticity, sleep quality, and overall vitality.
How Much to Take
Frequency
- Morning: Upon waking
- Post-workout: For recovery
- Before bed: Natural GH pulse
Timing
Empty stomach only - no food 60 minutes before/after injection
Adjustment
Start low: Begin with 100 mcg to assess tolerance
How Long to Use It
- Standard Cycle: Use for 8-12 weeks, followed by a 4-week break
- Extended Use: Can extend up to 16 weeks for advanced users
- Repeat Cycles: Can be cycled multiple times per year with proper breaks
- Results Timeline: Initial effects within 1-2 weeks
Cycling is Important
Don't exceed recommended cycle length to avoid desensitization. Take breaks between cycles to reset receptors.
Need-to-Know Information
How It Works
- GHRP-2 mimics ghrelin, the "hunger hormone," to stimulate GH release
- Creates natural GH pulses rather than constant elevation
- Also suppresses somatostatin, which normally inhibits GH production
Key Benefits
- Growth Hormone Release: 7-15x increase in natural GH production
- IGF-1 Production: Elevated IGF-1 levels for anabolic effects
- Appetite Stimulation: Moderate increase in hunger (less than GHRP-6)
- Sleep Enhancement: Deeper, more restorative sleep
Who Should Avoid It
- Pregnant or breastfeeding individuals
- Those with active cancer or tumor growth
- People with severe insulin resistance or diabetes
Possible Side Effects
- Increased appetite (usually moderate)
- Water retention (mild)
- Tingling in hands/feet at high doses
- Temporary lethargy after injection
Storage & Injection
Mixing Instructions
Use bacteriostatic water to reconstitute. Add 2 mL to a 5 mg vial for 2.5 mg/mL concentration.
Storage
Mixed vials: fridge for 30 days. Unmixed powder: freezer for 1 year.
Injection Sites
Subcutaneous in stomach area, thigh, or upper arm. Rotate sites to prevent tissue damage.
Method
Clean site with alcohol. Pinch skin, insert at 45-degree angle, inject slowly.
Critical Timing
Empty stomach only - avoid high blood sugar, don't inject after eating carbs.
Example Schedule
Daily Protocol
If You Miss a Dose
Take as soon as you remember if it's been less than 2 hours. Otherwise, skip and continue with your normal schedule. Don't double dose.
Extra Tips for Best Results
Stack with CJC-1295
Combine 100 mcg GHRP-2 with 100 mcg CJC-1295 (no DAC) for synergistic effect. Can mix in same syringe.
Optimize Natural GH
Get 7-9 hours quality sleep. Keep body fat under 15% (men) or 25% (women). Avoid alcohol around injection times.
Monitor Your Response
Start with lower dose (100 mcg) to assess tolerance. Increase gradually if needed. Watch for water retention or joint pain.
Track Progress
Monitor body composition changes. Note improvements in recovery and sleep quality. Keep injection log for consistency.
Expected Results Timeline
Week 1-2: Improved sleep quality and recovery. Week 3-4: Increased energy and appetite. Week 6-8: Noticeable body composition changes. Week 8-12: Significant muscle gains and fat loss.
Important Safety Information
GHRP-2 is not FDA approved for human therapeutic use. Always consult healthcare providers before use, especially if you have medical conditions or take other medications. Follow institutional safety protocols.
Medical Disclaimer
Clinical data presented is from peer-reviewed studies. Individual results may vary. Consult healthcare professionals before starting treatment. This information is for educational purposes only.