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Peptide Database

Adipotide
Weight Management
AOD-9604
Weight Management
BPC-157
Healing & Recovery
Cagrilintide
Weight Management
CJC-1295
Growth Hormone
DSIP
Sleep & Recovery
Epithalon
Anti-Aging
GHK-Cu
Anti-Aging
GHRP-2
Growth Hormone
HCG
Hormone Support
Hexarelin
Growth Hormone
HGH
Growth Hormone
IGF-1 LR3
Growth Hormone
Kisspeptin
Hormone Support
Melanotan-2
Cosmetic
MOTS-C
Metabolic
NAD+
Anti-Aging
Oxytocin Acetate
Hormone Support
PEG-MGF
Recovery
PT-141
Sexual Health
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Snap-8
Cosmetic
SS-31
Mitochondrial
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Thymosin Alpha-1
Immune
Tirzepatide
Weight Management
Total Peptides: 31
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GHRP-2
EfficacyHigh
Studies5
Participants98
StatusAvailable

GHRP-2

D-alanyl-D-2-naphthylalanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide

GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide developed as a second-generation growth hormone secretagogue by Bowers and colleagues in the early 1990s. Also known as pralmorelin in clinical literature, it potently stimulates growth hormone release through GHS-R1a receptor activation. GHRP-2 incorporates D-amino acids for enhanced stability and resistance to enzymatic degradation, making it significantly more potent than earlier analogs like GHRP-6.

Clinical Benefits

Potent growth hormone release (10-15 fold increase in animal studies)
Lean muscle mass increase (20-25% in research models)
Significant fat reduction (15-20% decrease in studies)
Enhanced IGF-1 production (30-40% increase after 24 hours)
Improved metabolic function and energy balance
Potential neuroprotective effects via BDNF upregulation

Mechanism of Action

GHRP-2 functions as a potent growth hormone secretagogue by binding to and activating the growth hormone secretagogue receptor (GHS-R1a) located in the anterior pituitary gland and hypothalamus. This activation triggers calcium influx and subsequent growth hormone release through a pathway distinct from growth hormone-releasing hormone (GHRH). GHRP-2 also mimics ghrelin's bioactive motif, engaging ghrelin pathways to influence appetite regulation and metabolic function. The peptide's unique structure, incorporating D-amino acids, provides resistance to peptidase degradation while maintaining high receptor affinity and bioactivity.

Key Action: Growth hormone releasing peptide - potent GH secretagogue via growth hormone secretagogue receptor

Proven Results

%
Maximum Weight Loss
Clinical research data
0%
Diabetes Risk Reduction
Clinical research data
98
Total Participants
Research studies
0%
CV Risk Reduction
Clinical data

Medical Disclaimer

GHRP-2 is an investigational research compound not approved by the FDA for human therapeutic use. This information is for educational purposes only and should not be construed as medical advice. Any use should occur only under medical supervision in approved research settings.