TB-500
Thymosin Beta-4
TB-500 is a synthetic version of thymosin beta-4, a naturally occurring protein that plays a crucial role in wound healing and tissue repair. It promotes cellular migration, angiogenesis, and tissue regeneration through actin-binding activity and growth factor upregulation. Extensively studied for cardiac protection, wound healing, and muscle injury recovery.
TB-500 Dosing Guide
Primary Benefits
- Accelerated wound healing and tissue repair
- Enhanced cellular migration to injury sites
- Promotes angiogenesis (new blood vessel formation)
- Reduces scar tissue formation
- Improves tissue elasticity and function
How It Works
TB-500 functions as an actin-binding protein that regulates cellular migration and tissue repair processes. It promotes the upregulation of key growth factors including VEGF (vascular endothelial growth factor), IGF-1 (insulin-like growth factor), and FGF (fibroblast growth factor). TB-500 enhances angiogenesis through VEGF-mediated pathways, accelerates collagen synthesis, and modulates inflammatory responses to optimize healing outcomes.
Quick Reference
Typical Dosage Range
Loading protocol typically begins with 2.0-2.5 mg administered 2-3 times weekly for 2-4 weeks. Maintenance dosing ranges from 2.0 mg twice weekly to 2.0 mg once weekly depending on healing goals. Acute injury protocols may use 2.5 mg twice weekly initially. Total treatment duration varies from 4-12 weeks based on healing progress and therapeutic goals.
Administration Methods
Subcutaneous injection is most common, using insulin-type syringes in the abdomen, thigh, or upper arm. Intramuscular injection may be preferred for muscle injuries, using slightly larger needles. Rotate injection sites to prevent tissue irritation. Reconstitute lyophilized powder with bacteriostatic water. Store reconstituted solution refrigerated and use within recommended timeframe.
Medical Disclaimer
TB-500 is a research chemical not approved by the FDA for human therapeutic use. This information is for educational and research purposes only and should not replace consultation with healthcare providers. Individual results may vary significantly. Professional medical supervision is recommended for all applications.