Peptide Comparison
Pentadecapeptide (BPC Analog)vsTB-500
Nature's tissue-healing peptide from gastric juice—a 15-amino acid powerhouse for recovery
A powerful fragment of thymosin beta-4 that acts like your body's repair signal—speeding up healing of muscles, tendons, and tissues by promoting cell migration and new blood vessel growth right where you need it most.
At a Glance
Quick
comparison
Dose Range
Pentadecapeptide (BPC Analog)
250 mcg–1000 mcg mcg
TB-500
2–5 mg
Frequency
Pentadecapeptide (BPC Analog)
Once daily
TB-500
Twice weekly
Administration
Pentadecapeptide (BPC Analog)
Intramuscular injection
TB-500
Subcutaneous injection
Cycle Length
Pentadecapeptide (BPC Analog)
Ongoing/indefinite
TB-500
4-6 weeks
Onset Speed
Pentadecapeptide (BPC Analog)
Moderate (1-2 weeks)
TB-500
Moderate (1-2 weeks)
Evidence Level
Pentadecapeptide (BPC Analog)
Moderate human trials (Phase 1-2)
TB-500
Moderate human trials (Phase 1-2)
Efficacy
Benefit
ratings
Tissue Repair & Recovery
Angiogenesis (Blood Vessel Formation)
Anti-Inflammatory Effects
Healing Speed
Tissue Repair
Anti-Scarring
Technical Data
Compound
specifications
Pentadecapeptide (BPC Analog)
Molecular Formula
C62H98N16O22
Molecular Weight
1419.5 g/mol
Half-Life
Not precisely established in humans; likely hours to days depending on tissue depot
Bioavailability
Significantly improved with parenteral administration (injection); poor with oral route
CAS Number
Not assigned (research compound)
TB-500
Molecular Formula
C38H68N10O14
Molecular Weight
889.01 g/mol
Half-Life
2-3 days (systemic)
Bioavailability
High via subcutaneous injection (~100%)
CAS Number
885340-08-9
Protocols
Dosing
tiers
Pentadecapeptide (BPC Analog)
TB-500
Applications
Best
suited for
Pentadecapeptide (BPC Analog)
Recovering from sports injuries or muscle strains
Pentadecapeptide (BPC Analog) is particularly well-suited for individuals focused on recovering from sports injuries or muscle strains. Research and clinical experience suggest meaningful benefits in this area when used as part of a comprehensive treatment approach.
Supporting post-surgery tissue repair
Pentadecapeptide (BPC Analog) is particularly well-suited for individuals focused on supporting post-surgery tissue repair. Research and clinical experience suggest meaningful benefits in this area when used as part of a comprehensive treatment approach.
Accelerating tendon and ligament healing
Pentadecapeptide (BPC Analog) is particularly well-suited for individuals focused on accelerating tendon and ligament healing. Research and clinical experience suggest meaningful benefits in this area when used as part of a comprehensive treatment approach.
Improving overall recovery speed
Pentadecapeptide (BPC Analog) is particularly well-suited for individuals focused on improving overall recovery speed. Research and clinical experience suggest meaningful benefits in this area when used as part of a comprehensive treatment approach.
TB-500
Athletes Recovering from Muscle Injuries
If you've pulled a hamstring, strained your back, or torn a muscle, TB-500 helps accelerate the healing process by promoting cell migration to the injury site and supporting new blood vessel growth. It's especially useful for injuries that just won't seem to fully heal.
Tendon and Ligament Problems
Tendons and ligaments are notoriously slow healers because they have poor blood supply. TB-500 promotes angiogenesis (new blood vessel formation) and helps repair these stubborn connective tissue injuries—think Achilles tendonitis, tennis elbow, or rotator cuff issues.
Post-Surgical Recovery
After surgery, your body needs to repair a lot of tissue quickly. TB-500 supports wound healing, reduces inflammation, and may help minimize scar tissue formation. Some protocols use it alongside traditional recovery to potentially speed up the healing timeline.
Chronic Inflammation and Slow Healers
Some people just heal slowly—whether due to age, diabetes, or other factors. TB-500 helps regulate the inflammatory response and promotes the cellular processes needed for tissue repair. It essentially tells your body to focus healing resources where they're needed most.
Safety Profile
Side
effects
Pentadecapeptide (BPC Analog)
Common
- Injection site irritation
- Headache
- Nausea
Uncommon
- Dizziness
- Mood or anxiety changes
Serious
- Allergic reaction
TB-500
Common
- Injection site redness
- Mild fatigue or lethargy
- Mild headache
- Slight flushing
Uncommon
- Head rush or lightheadedness
- Temporary nausea
Serious
- Allergic reaction
Research Status
Safety
& evidence
Pentadecapeptide (BPC Analog)
Evidence Level
Moderate human trials (Phase 1-2)
FDA Status
Research compound
Safety Overview
BPC-157 analogs show favorable safety in animal toxicity studies with LD50 >1000 mg/kg (oral, rats). No serious adverse events in limited clinical case reports; mild local injection site effects observed. Gastroprotective mechanism suggests low systemic toxicity; rapid hepatic metabolism limits systemic exposure. Preclinical studies show no mutagenicity, carcinogenicity, or teratogenicity; reproductive safety appears favorable.
Contraindications
- xActive cancer or high cancer risk
- xPregnancy or breastfeeding
- xKnown hypersensitivity to peptides
TB-500
Evidence Level
Moderate human trials (Phase 1-2)
FDA Status
Research compound
Safety Overview
TB-500 has shown a good safety profile across preclinical studies and limited human research. It's a fragment of thymosin beta-4, a naturally occurring protein in your body involved in healing. Most side effects are mild and transient, primarily injection site reactions. However, large-scale clinical trials are still needed to fully establish its safety profile in humans.
Contraindications
- xPregnancy or planning to become pregnant
- xCurrently breastfeeding
- xActive cancer or history of cancer
- xKnown allergy to peptide components
- xChildren and adolescents
Decision Guide
Which is
right for you?
Choose Pentadecapeptide (BPC Analog) if...
- Recovering from sports injuries or muscle strains
- Supporting post-surgery tissue repair
- Accelerating tendon and ligament healing
- Improving overall recovery speed
Choose TB-500 if...
- Accelerating injury recovery
- Tendon and ligament healing
- Reducing chronic inflammation
- Post-surgical recovery support