Eagle LogoPEPTIDE INITIATIVE

Peptide Database

Goals
Fat LossMuscle BuildingInjury HealingAnti-AgingCognitive EnhancementSleep OptimizationImmune SupportGut HealingSkin RejuvenationSexual Health
Peptides
5-Amino-1MQ
Weight Management
Abarelix
Hormone Support
Acetyl Hexapeptide-3 (Argireline)
Cosmetic
Adipotide
Weight Management
Adrenomedullin
Healing & Recovery
Alexamorelin
Growth Hormone
Angiotensin (1-7)
Healing & Recovery
AOD-9604
Weight Management
Apelin-13
Healing & Recovery
ARA-290 (Cibinetide)
Healing & Recovery
Bestatin (Ubenimex)
Immune
BPC-157
Healing & Recovery
Buserelin
Hormone Support
Cagrilintide
Weight Management
CagriSema
Weight Management
Capromorelin
Growth Hormone
Cartalax
Anti-Aging
Cathelicidin (hCAP-18 / Synthetic Derivatives)
Immune
Cerebrolysin
Cognitive
Cerluten
Cognitive
Cetrorelix
Hormone Support
Chonluten
Immune
CJC-1295 (No DAC)
Growth Hormone
CJC-1295 with DAC
Growth Hormone
Cortexin
Cognitive
Crystagen
Immune
Daptomycin
Immune
Defensin (HBD-2)
Immune
Defensin (HBD-3)
Immune
Degarelix
Hormone Support
Dihexa
Cognitive
DSIP (Delta Sleep-Inducing Peptide)
Sleep & Recovery
Dulaglutide
Weight Management
Enalapril
Healing & Recovery
Epithalon
Anti-Aging
Exenatide
Weight Management
Fertirelin
Hormone Support
FOXO4-DRI
Anti-Aging
Ganirelix
Hormone Support
GHK-Cu (Copper Peptide)
Cosmetic
GHRH (1-29)
Growth Hormone
GHRP-2
Growth Hormone
GHRP-6 (Growth Hormone Releasing Peptide-6)
Growth Hormone
Glutathione
Anti-Aging
Gonadorelin (GnRH)
Hormone Support
Gramicidin
Immune
Hexarelin
Growth Hormone
Human Chorionic Gonadotropin (HCG)
Hormone Support
Human Growth Hormone (HGH)
Growth Hormone
IGF-1 LR3
Growth Hormone
Immunoxel (Dzherelo)
Immune
Imunofan
Immune
Intermedin (Adrenomedullin-2)
Healing & Recovery
Ipamorelin
Growth Hormone
Kisspeptin-10
Sexual Health
KPV (Alpha-MSH Fragment)
Healing & Recovery
Lactoferricin B
Immune
Larazotide
Healing & Recovery
Lentinan
Immune
Leuphasyl
Cosmetic
Leuprolide
Hormone Support
Liraglutide
Weight Management
Livagen
Anti-Aging
Lixisenatide
Weight Management
LL-37
Immune
Macimorelin
Growth Hormone
Magainin-2
Immune
Mazdutide
Weight Management
Melanotan-2
Cosmetic
MK-677 (Ibutamoren)
Growth Hormone
MOTS-c
Metabolic
Myristoyl Pentapeptide-17
Cosmetic
N-Acetyl Selank
Cognitive
N-Acetyl Semax Amidate
Cognitive
NAD+
Mitochondrial
Nafarelin
Hormone Support
Natriuretic Peptide (ANP)
Healing & Recovery
Nesiritide (BNP)
Healing & Recovery
Nisin
Immune
Noopept (Omberacetam)
Cognitive
Orforglipron
Weight Management
Ovagen
Anti-Aging
Oxytocin Acetate
Hormone Support
P21 (P021)
Cognitive
PACAP-38
Healing & Recovery
Palmitoyl Oligopeptide
Cosmetic
Palmitoyl Pentapeptide-4 (Matrixyl)
Cosmetic
Palmitoyl Tetrapeptide-7
Cosmetic
Palmitoyl Tripeptide-1
Cosmetic
Pancragen
Metabolic
PEG-MGF
Healing & Recovery
Pemvidutide
Weight Management
Pentadecapeptide (BPC Analog)
Healing & Recovery
Pidotimod
Immune
Pinealon
Cognitive
PNC-27
Immune
Polymyxin B
Immune
Pralmorelin (GHRP-2)
Growth Hormone
Pramlintide
Weight Management
Prostamax
Hormone Support
PT-141 (Bremelanotide)
Sexual Health
Relaxin-2 (Serelaxin)
Healing & Recovery
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Setmelanotide
Weight Management
SLU-PP-332
Metabolic
SM-130686
Growth Hormone
Snap-8
Cosmetic
SS-31 (Elamipretide)
Mitochondrial
Substance P Antagonists
Healing & Recovery
Survodutide
Weight Management
SYN-AKE
Cosmetic
Tabimorelin
Growth Hormone
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Testagen
Hormone Support
Thymalin
Immune
Thymopentin (TP-5)
Immune
Thymopoietin
Immune
Thymosin Alpha-1
Immune
Thymosin Beta-4
Healing & Recovery
Thymulin (FTS)
Immune
Thymulin Analog (PAT)
Healing & Recovery
Tirzepatide
Weight Management
Tripeptide-29
Cosmetic
Triptorelin
Hormone Support
Ularitide
Healing & Recovery
Urocortin
Healing & Recovery
Ventfort
Anti-Aging
Vesilute
Hormone Support
Vilon
Immune
VIP (Vasoactive Intestinal Peptide)
Healing & Recovery
Xenin-25
Metabolic
Ziconotide (Prialt)
Healing & Recovery
Total Peptides: 137
Back to Home

Condition Spotlight

Peripheral
Neuropathy

Peripheral neuropathy affects 20-30 million Americans, causing numbness, tingling, pain, and weakness that slowly steals your ability to move freely, feel normally, and live without discomfort. For diabetics alone, this neurological damage affects half of all patients. The good news? Your nerves have remarkable capacity to regenerate when given the right support.

Written by Michael Carroll — Owner, Director of Research · Reviewed by the Peptide Initiative Research Team · Editorial standards

The Problem

Your Nerves Are
Struggling to Communicate

Pain & Tingling

Sharp, burning, or pins-and-needles sensations

Numbness

Loss of feeling in hands and feet

Weakness

Difficulty with coordination and strength

Understanding Nerve Damage

When Nerves Stop Talking to Your Brain

Your peripheral nerves are like communication cables running from your brain and spinal cord to every part of your body. They carry signals that let you feel touch, temperature, and pain - and they control your muscles so you can move. When you have peripheral neuropathy, these cables get damaged. This can happen from diabetes, infections like Lyme disease, toxins, repetitive stress, or simply the wear and tear of aging. The myelin sheath (the protective coating around nerve fibers) breaks down. The nerve cells themselves atrophy - they shrink and lose function. Communication between your nerves and brain becomes spotty and unreliable.

"Your nerves have extraordinary capacity to heal - they just need the right growth signals."

The result? Numbness where you should feel sensation. Pain where there shouldn't be pain. Weakness in muscles that seem to forget how to work. This is where peptide therapy comes in - each one stimulates nerve regeneration from a different angle, giving your nervous system the biological signals it needs to repair and rebuild.

The Solutions

4 Peptides
4 Angles of Attack

1991

BPC-157

The Nerve Regenerator

A peptide naturally found in gastric juices that powerfully stimulates nerve growth and tissue healing across the entire body.

Role

Planting seeds for new nerve growth

1981

TB-500

The Tissue Healer

A synthetic version of Thymosin Beta-4, a peptide that promotes cellular migration, tissue repair, and angiogenesis throughout the body.

Role

Coordinator organizing the repair team

1954

NGF (Nerve Growth Factor)

The Nerve Rebuilding Blueprint

A naturally occurring protein that is essential for nerve cell survival, growth, and maintenance. One of the most studied nerve regeneration molecules.

Role

The master instruction manual for nerve growth

Learn more

1957

IGF-1 / IGF-1 LR3

The Growth Amplifier

Insulin-like Growth Factor 1 is a powerful anabolic hormone that promotes growth and repair of multiple tissue types, including nerve tissue.

Role

Multiplying the building materials available

Learn more

The Strategy

How They Work Together
Together

PeptidePrimary RoleAnalogy
BPC-157

The Nerve Regenerator

Planting seeds for new nerve growth

TB-500

The Tissue Healer

Coordinator organizing the repair team

NGF (Nerve Growth Factor)

The Nerve Rebuilding Blueprint

The master instruction manual for nerve growth

IGF-1 / IGF-1 LR3

The Growth Amplifier

Multiplying the building materials available

4 Angles of Attack

Direct Nerve Growth

BPC-157 and NGF directly stimulate axon growth and myelin repair

Tissue Coordination

TB-500 organizes the healing response and brings cells where they're needed

Anabolic Support

IGF-1 amplifies growth signals and provides metabolic resources

Multi-Level Regeneration

Together they address axon growth, myelin repair, inflammation reduction, and circulation

Important Considerations

Reality Check
What to Keep in Mind

Evidence Level: Preclinical

The evidence for these peptides in peripheral neuropathy comes primarily from animal models and cell studies. Human clinical trial data is limited but emerging.

Regeneration Takes Time

Growing new nerve tissue is a months-long process, not weeks. Patience and consistency with peptides and lifestyle support are essential.

Professional Guidance Required

Work with a healthcare provider experienced in peptide therapy. Proper dosing, cycling, and monitoring are critical for safety and efficacy.

This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before starting any new treatment.

Realistic Expectations

What to Expect: A Realistic Timeline

An honest breakdown based on research and clinical reports.

What's Happening Inside

The peptides are activating growth signaling pathways. Nerve growth factors are beginning to accumulate. Your cells are receiving the 'grow' signal, but new nerve tissue hasn't yet formed.

What You Might Notice

  • Possibly no obvious changes yet - this is foundational work
  • Some people report subtle shifts in symptoms (less constant pain)
  • Sleep may improve slightly
  • Early immune response to healing may cause mild inflammation

Watch For

Some people experience temporary increased pain or tingling as nerves become more sensitive before they strengthen. This can indicate the peptides are working.

Realistic Expectations

You're laying neural groundwork. Patience is essential here.

Administration Guide

Dosing Protocols & Timing

General guidelines based on research literature and clinical reports. Work with a healthcare provider experienced in peptide therapy to customize for your situation.

Important: These are general guidelines. Don't self-prescribe based on internet articles. Work with a qualified healthcare provider.

BPC-157

250-500 mcg per dose

Common Protocols

  • Conservative start: 500 mcg subcutaneous injection once daily
  • Standard: 500 mcg twice daily (morning and evening)
  • Higher dose: 1000 mcg daily, typically split into two doses

Timing Considerations

  • Can be taken at any time, though morning dosing is often preferred
  • Oral BPC-157 is available and may be preferred by some (250-500 mcg daily)
  • Consistency of dosing more important than specific timing
  • Some evidence suggests taking with meals may improve absorption for oral form

Cycling

Often cycled 8-12 weeks on, 4 weeks off due to preclinical status. Some practitioners use continuous low-dose protocols.

BPC-157 research in fibromyalgia is very limited. Dosing based primarily on other neuropathic conditions. Requires healthcare provider oversight.

Beyond Peptides

Lifestyle Strategies for Living Well

Peptides work best as part of a comprehensive approach. Click each category to explore evidence-based strategies.

At a Glance

Quick Reference Card

Peptide Overview

PeptideWhat It DoesTypical DoseTiming
BPC-157
The Nerve Regenerator250-500 mcg per doseCan be taken at any time, though morning dosing is often preferred
TB-500
The Tissue Healer2-5 mg per weekConsistent timing helps maintain steady state - same days/times each week
NGF (Nerve Growth Factor)
The Nerve Rebuilding Blueprint0.3-1 mcg per kg of body weightOnce daily administration is standard
IGF-1 / IGF-1 LR3
The Growth Amplifier50-200 mcg per applicationBest applied to clean, dry scalp

Early Wins to Watch

  • Reduced neuropathic pain episodes
  • Improved sleep quality
  • Changes in tingling sensations
  • Better temperature sensation returning

Support Stack

Alpha-lipoic acidB vitamins (B1, B6, B12)MethylcobalaminAcetyl-L-carnitineCurcuminMagnesiumOmega-3 fish oil

Lifestyle Priorities

  • Paced, consistent movement
  • Adequate quality sleep
  • Anti-inflammatory nutrition with adequate protein
  • Glucose control (if diabetic)
  • Pain management for improved quality of life

Peripheral neuropathy affects millions of Americans, but your nerves have remarkable capacity to regenerate when given proper biological support. These peptides represent a scientifically-grounded approach to address the core mechanism of nerve damage. Recovery takes time, but many people experience substantial improvements in sensation, pain, and function.

Stay consistent with peptide protocols, support your healing with proper nutrition and sleep, and remember that nerve regeneration is one of the most studied and reproducible biological processes. You can heal.