Peptide Comparison
CerlutenvsSelank
Brain-derived peptide bioregulator complex containing AED, KED, AEDG, and KE peptides that promote neurogenesis through histone binding, restore dendritic spine architecture under neurotoxic conditions, and enhance cognitive recovery in stroke and brain injury patients
A clever brain-boosting peptide derived from your immune system's natural tuftsin molecule—it calms anxiety and sharpens your mind without the drowsiness or addiction risks of traditional anti-anxiety medications.
At a Glance
Quick
comparison
Dose Range
Cerluten
10–20 mg
Selank
250–500 mcg
Frequency
Cerluten
Once daily
Selank
Once daily
Administration
Cerluten
Oral (capsule)
Selank
Intranasal
Cycle Length
Cerluten
8-12 weeks
Selank
4-6 weeks
Onset Speed
Cerluten
Gradual (3-4 weeks)
Selank
Rapid (hours to days)
Evidence Level
Cerluten
Limited human trials
Selank
Limited human trials
Efficacy
Benefit
ratings
Neuroprotection
Post-Stroke Recovery
Brain Cell Renewal
Anxiety Relief
Cognitive Enhancement
Immune Support
Technical Data
Compound
specifications
Cerluten
Molecular Formula
C11H17N3O8 (representative primary component)
Molecular Weight
319.3 g/mol (representative; complex contains peptides from 200-500 Da)
Half-Life
Short plasma half-life for individual peptide components (minutes to hours); biological effects persist for weeks to months through epigenetic modifications to gene expression
Bioavailability
Oral and sublingual absorption via intestinal peptide transporters (PepT1); component peptides cross the blood-brain barrier; sublingual form bypasses first-pass hepatic metabolism
CAS Number
75007-24-8
Selank
Molecular Formula
C33H57N11O9
Molecular Weight
751.9 g/mol
Half-Life
2-3 minutes (plasma); effects last hours due to downstream signaling
Bioavailability
High intranasal absorption; near 100% subcutaneous
CAS Number
129954-34-3
Protocols
Dosing
tiers
Cerluten
Selank
Applications
Best
suited for
Cerluten
Cognitive recovery following stroke or traumatic brain injury
Cerluten is particularly well-suited for individuals focused on cognitive recovery following stroke or traumatic brain injury. Research and clinical experience suggest meaningful benefits in this area when used as part of a comprehensive treatment approach.
Neuroprotection against age-related cognitive decline and neurodegeneration
Cerluten is particularly well-suited for individuals focused on neuroprotection against age-related cognitive decline and neurodegeneration. Research and clinical experience suggest meaningful benefits in this area when used as part of a comprehensive treatment approach.
Supporting neurogenesis and neuronal repair in aging brain tissue
Cerluten is particularly well-suited for individuals focused on supporting neurogenesis and neuronal repair in aging brain tissue. Research and clinical experience suggest meaningful benefits in this area when used as part of a comprehensive treatment approach.
Comprehensive bioregulatory approach to brain aging using multiple complementary peptide components
Cerluten is particularly well-suited for individuals focused on comprehensive bioregulatory approach to brain aging using multiple complementary peptide components. Research and clinical experience suggest meaningful benefits in this area when used as part of a comprehensive treatment approach.
Selank
Anxiety Without the Fog
If traditional anti-anxiety medications leave you feeling sedated, foggy, or 'not yourself,' Selank offers a refreshing alternative. It calms anxious thoughts while keeping your mind sharp—like turning down the volume on worry without muting your brain.
Cognitive Performers
Students, professionals, and anyone facing demanding mental tasks love Selank for its dual action. It simultaneously reduces performance anxiety while enhancing memory and focus—the best of both worlds when you need to think clearly under pressure.
Stress Resilience Seekers
Chronic stress wreaks havoc on your brain. Selank helps protect against stress-induced cognitive decline by supporting BDNF levels and modulating your stress response. Think of it as building a buffer between you and life's daily pressures.
Natural Approach Enthusiasts
Derived from tuftsin—a natural peptide your own immune system produces—Selank appeals to those seeking more 'natural' solutions. It works with your body's existing systems rather than overriding them like synthetic drugs.
Safety Profile
Side
effects
Cerluten
Common
- Mild headache
- Mild drowsiness
- Mild GI discomfort
- Vivid dreams
Uncommon
- Transient sleep pattern changes
Serious
- No documented serious adverse effects
Selank
Common
- Nasal irritation
- Mild fatigue
- Mild headache
- Injection site redness
Uncommon
- Vivid dreams
- Dizziness
Serious
- Allergic reaction
Research Status
Safety
& evidence
Cerluten
Evidence Level
Limited human trials
FDA Status
Research compound
Safety Overview
Cerluten is a peptide extract from cerebral tissue of young animals that is not FDA-approved and lacks rigorous clinical safety data. As an undefined mixture of peptides and proteins from animal sources, quality control and batch consistency cannot be guaranteed. Potential risks include allergic reactions to animal-derived proteins, contamination with microbial pathogens or prions, and unknown long-term immunological effects. No comprehensive safety studies have been conducted in humans, and the active pharmaceutical components have never been identified or standardized. The product exists primarily in Russian and Eastern European medical markets without Western regulatory oversight.
Contraindications
- xKnown hypersensitivity to peptide bioregulators or bovine-derived products
- xPregnancy and breastfeeding — insufficient reproductive safety data
- xActive CNS infection — treat infection before initiating peptide bioregulator therapy
- xPrion disease concerns — although manufacturing processes include purification to remove proteins > 5 kDa, individuals with heightened prion risk should exercise caution
Selank
Evidence Level
Limited human trials
FDA Status
Research compound
Safety Overview
Selank has demonstrated a favorable safety profile across multiple Russian clinical studies spanning over two decades. In human trials comparing Selank to traditional anxiolytics like phenazepam, Selank showed comparable anti-anxiety effects with significantly better tolerability and no sedation, dependence, or memory impairment. The peptide has been approved for clinical use in Russia since the 1990s for anxiety and neurasthenia.
Contraindications
- xPregnancy or planning to become pregnant
- xCurrently breastfeeding
- xKnown allergy to peptide components
- xChildren and adolescents
- xSevere psychiatric disorders requiring immediate intervention
Decision Guide
Which is
right for you?
Choose Cerluten if...
- Cognitive recovery following stroke or traumatic brain injury
- Neuroprotection against age-related cognitive decline and neurodegeneration
- Supporting neurogenesis and neuronal repair in aging brain tissue
- Comprehensive bioregulatory approach to brain aging using multiple complementary peptide components
Choose Selank if...
- Anxiety relief without sedation
- Cognitive enhancement and focus
- Memory improvement
- Stress resilience