Peptide Comparison
DSIP (Delta Sleep-Inducing Peptide)vsSelank
A naturally occurring brain peptide that helps you fall into deep, restorative sleep by gently nudging your body's own sleep-wake systems—without the groggy hangover of traditional sleep aids.
A clever brain-boosting peptide derived from your immune system's natural tuftsin molecule—it calms anxiety and sharpens your mind without the drowsiness or addiction risks of traditional anti-anxiety medications.
At a Glance
Quick
comparison
Dose Range
DSIP (Delta Sleep-Inducing Peptide)
100–300 mcg
Selank
250–500 mcg
Frequency
DSIP (Delta Sleep-Inducing Peptide)
Once daily
Selank
Once daily
Administration
DSIP (Delta Sleep-Inducing Peptide)
Subcutaneous injection
Selank
Intranasal
Cycle Length
DSIP (Delta Sleep-Inducing Peptide)
4-6 weeks
Selank
4-6 weeks
Onset Speed
DSIP (Delta Sleep-Inducing Peptide)
Rapid (hours to days)
Selank
Rapid (hours to days)
Evidence Level
DSIP (Delta Sleep-Inducing Peptide)
Limited human trials
Selank
Limited human trials
Efficacy
Benefit
ratings
Sleep Quality
Stress Protection
Safety Profile
Anxiety Relief
Cognitive Enhancement
Immune Support
Technical Data
Compound
specifications
DSIP (Delta Sleep-Inducing Peptide)
Molecular Formula
C35H48N10O15
Molecular Weight
848.81 g/mol
Half-Life
7-8 minutes (but effects last many hours due to downstream signaling)
Bioavailability
Variable; best with subcutaneous or intravenous administration
CAS Number
62568-57-4
Selank
Molecular Formula
C33H57N11O9
Molecular Weight
751.9 g/mol
Half-Life
2-3 minutes (plasma); effects last hours due to downstream signaling
Bioavailability
High intranasal absorption; near 100% subcutaneous
CAS Number
129954-34-3
Protocols
Dosing
tiers
DSIP (Delta Sleep-Inducing Peptide)
Selank
Applications
Best
suited for
DSIP (Delta Sleep-Inducing Peptide)
Chronic Insomnia
DSIP shines brightest for people who've struggled with sleep for months or years. Unlike sleeping pills that force you unconscious, DSIP helps restore your brain's natural ability to enter deep sleep. Human studies showed chronic insomniacs experienced longer sleep duration, fewer nighttime awakenings, and better overall sleep quality.
Jet Lag and Shift Work
When your internal clock is out of sync with the real world, DSIP can help reset it. The peptide influences circadian rhythm regulation, making it valuable for travelers crossing time zones or night-shift workers trying to sleep during the day. It helps your body understand when it's time to sleep.
Stress-Related Sleep Problems
Can't sleep because your mind won't stop racing? DSIP has documented stress-protective properties. Studies show it helps modulate the body's stress response, making it easier to wind down when life gets hectic. It's not just about sleep—it's about helping your whole system calm down.
Age-Related Sleep Changes
As we get older, deep sleep becomes harder to achieve. DSIP may help older adults reclaim some of that restorative delta-wave sleep that naturally declines with age. Research also shows impressive antioxidant effects, which adds anti-aging benefits on top of better sleep.
Athletic Recovery
Deep sleep is when your body does most of its repair work. By enhancing delta-wave sleep, DSIP can indirectly support recovery from intense training. Better sleep means better growth hormone release, better tissue repair, and better performance the next day.
Selank
Anxiety Without the Fog
If traditional anti-anxiety medications leave you feeling sedated, foggy, or 'not yourself,' Selank offers a refreshing alternative. It calms anxious thoughts while keeping your mind sharp—like turning down the volume on worry without muting your brain.
Cognitive Performers
Students, professionals, and anyone facing demanding mental tasks love Selank for its dual action. It simultaneously reduces performance anxiety while enhancing memory and focus—the best of both worlds when you need to think clearly under pressure.
Stress Resilience Seekers
Chronic stress wreaks havoc on your brain. Selank helps protect against stress-induced cognitive decline by supporting BDNF levels and modulating your stress response. Think of it as building a buffer between you and life's daily pressures.
Natural Approach Enthusiasts
Derived from tuftsin—a natural peptide your own immune system produces—Selank appeals to those seeking more 'natural' solutions. It works with your body's existing systems rather than overriding them like synthetic drugs.
Safety Profile
Side
effects
DSIP (Delta Sleep-Inducing Peptide)
Common
- Mild headache
- Brief dizziness or lightheadedness
- Flushing or warmth
- Injection site reactions
Uncommon
- Vivid dreams
- Mild nausea
Serious
- Allergic reaction
Selank
Common
- Nasal irritation
- Mild fatigue
- Mild headache
- Injection site redness
Uncommon
- Vivid dreams
- Dizziness
Serious
- Allergic reaction
Research Status
Safety
& evidence
DSIP (Delta Sleep-Inducing Peptide)
Evidence Level
Limited human trials
FDA Status
Research compound
Safety Overview
DSIP has an excellent safety record across decades of research. In human studies, it was described as 'incredibly safe' with no lethal dose ever identified in animal studies. Side effects are generally mild and temporary—mostly headache, brief dizziness, or flushing. The peptide works by supporting natural sleep processes rather than forcing sedation, which is why it doesn't cause the dependency or withdrawal issues seen with pharmaceutical sleep aids.
Contraindications
- xPregnancy or breastfeeding
- xKnown hypersensitivity to peptides
- xSevere respiratory disorders
- xUntreated sleep apnea
- xActive psychiatric conditions without medical supervision
Selank
Evidence Level
Limited human trials
FDA Status
Research compound
Safety Overview
Selank has demonstrated a favorable safety profile across multiple Russian clinical studies spanning over two decades. In human trials comparing Selank to traditional anxiolytics like phenazepam, Selank showed comparable anti-anxiety effects with significantly better tolerability and no sedation, dependence, or memory impairment. The peptide has been approved for clinical use in Russia since the 1990s for anxiety and neurasthenia.
Contraindications
- xPregnancy or planning to become pregnant
- xCurrently breastfeeding
- xKnown allergy to peptide components
- xChildren and adolescents
- xSevere psychiatric disorders requiring immediate intervention
Decision Guide
Which is
right for you?
Choose DSIP (Delta Sleep-Inducing Peptide) if...
- Improving sleep quality and duration
- Resetting disrupted circadian rhythms
- Managing stress and improving resilience
- Supporting healthy aging through better sleep
Choose Selank if...
- Anxiety relief without sedation
- Cognitive enhancement and focus
- Memory improvement
- Stress resilience