Peptide Comparison
CJC-1295 with DACvsIpamorelin
Long-acting growth hormone releaser that works around the clock to boost your body's natural GH production with just one or two injections per week.
A uniquely selective growth hormone booster that tells your pituitary to release more GH without messing with your cortisol or other hormones—making it the 'clean' choice among growth hormone peptides.
At a Glance
Quick
comparison
Dose Range
CJC-1295 with DAC
1000–2000 mcg
Ipamorelin
100–300 mcg
Frequency
CJC-1295 with DAC
Twice weekly
Ipamorelin
Multiple times daily
Administration
CJC-1295 with DAC
Subcutaneous injection
Ipamorelin
Subcutaneous injection
Cycle Length
CJC-1295 with DAC
8-12 weeks
Ipamorelin
8-12 weeks
Onset Speed
CJC-1295 with DAC
Moderate (1-2 weeks)
Ipamorelin
Moderate (1-2 weeks)
Evidence Level
CJC-1295 with DAC
Moderate human trials (Phase 1-2)
Ipamorelin
Moderate human trials (Phase 1-2)
Efficacy
Benefit
ratings
GH Elevation
Convenience
Recovery Support
GH Selectivity
Safety Profile
Technical Data
Compound
specifications
CJC-1295 with DAC
Molecular Formula
C165H269N47O46
Molecular Weight
3647.28 g/mol
Half-Life
6-8 days
Bioavailability
~100% (subcutaneous)
CAS Number
863288-34-0
Ipamorelin
Molecular Formula
C38H49N9O5
Molecular Weight
711.85 g/mol
Half-Life
2 hours
Bioavailability
High when injected subcutaneously
CAS Number
170851-70-4
Protocols
Dosing
tiers
CJC-1295 with DAC
Ipamorelin
Applications
Best
suited for
CJC-1295 with DAC
Growth Hormone Optimization
CJC-1295 with DAC excels at providing a sustained, steady elevation of growth hormone levels. Unlike shorter-acting peptides that create brief spikes, the DAC modification keeps GH elevated for days, mimicking a more youthful hormone profile.
Muscle Building and Recovery
By increasing both GH and IGF-1 levels, this peptide supports protein synthesis and muscle repair. Users often notice improved recovery between workouts and better ability to build and maintain lean muscle mass.
Anti-Aging and Longevity
Growth hormone naturally declines with age, contributing to many signs of aging. CJC-1295 with DAC helps restore more youthful GH levels, potentially supporting better skin quality, energy levels, and overall vitality.
Body Composition Improvement
The combination of increased GH and IGF-1 promotes fat metabolism while preserving muscle tissue. Many users experience gradual fat loss, particularly in stubborn areas, while maintaining or building lean mass.
Convenient Weekly Dosing
Unlike peptides requiring daily or twice-daily injections, the extended half-life of CJC-1295 with DAC means just one or two injections per week provide continuous benefits. Ideal for those who want results without daily protocols.
Ipamorelin
Clean GH Boost Seekers
If you want the benefits of increased growth hormone without spiking cortisol or other stress hormones, Ipamorelin is uniquely selective. Unlike GHRP-2 or GHRP-6, it won't raise your cortisol levels even at doses 200 times higher than needed for GH release.
Recovery-Focused Athletes
Ipamorelin shines for athletes who want better recovery between training sessions. The GH boost helps repair muscle tissue faster, and since it doesn't mess with other hormones, you can use it consistently without the rollercoaster effects.
Anti-Aging Enthusiasts
Growth hormone naturally declines as we age, contributing to muscle loss, fat gain, and reduced vitality. Ipamorelin offers a gentle way to restore more youthful GH levels without the risks of actual HGH therapy.
Those Recovering from Steroid Use
Research shows Ipamorelin can help counteract the muscle and bone-weakening effects of glucocorticoid medications. If you've been on steroids for medical reasons, this peptide may help you rebuild what you've lost.
Safety Profile
Side
effects
CJC-1295 with DAC
Common
- Injection site reactions
- Water retention
- Flushing
- Tingling sensation
Uncommon
- Headaches
- Fatigue or lethargy
- Joint discomfort
Serious
- Carpal tunnel symptoms
- Blood glucose elevation
Ipamorelin
Common
- Mild headache
- Injection site reactions
- Water retention
- Increased appetite
Uncommon
- Tingling in hands or feet
- Joint stiffness
Serious
- Allergic reaction
Research Status
Safety
& evidence
CJC-1295 with DAC
Evidence Level
Moderate human trials (Phase 1-2)
FDA Status
Research compound
Safety Overview
CJC-1295 with DAC was evaluated in Phase 1-2 human clinical trials where it demonstrated a generally favorable safety profile. The most common adverse events were mild injection site reactions including temporary pain, swelling, and redness. No serious adverse events were reported in the published clinical studies. The compound was being developed for HIV-associated lipodystrophy before the program was discontinued.
Contraindications
- xActive cancer or history of malignancy
- xPregnancy or breastfeeding
- xPituitary tumors or disorders
- xDiabetic retinopathy
- xUncontrolled diabetes
Ipamorelin
Evidence Level
Moderate human trials (Phase 1-2)
FDA Status
Research compound
Safety Overview
Ipamorelin has shown a favorable safety profile in both animal and human studies. What makes it stand out is its remarkable selectivity—it releases growth hormone without significantly affecting cortisol, ACTH, or other hormones. In clinical trials, it was well-tolerated with mostly mild, temporary side effects. Phase 2 trials in patients recovering from surgery showed no significant safety concerns compared to placebo.
Contraindications
- xActive cancer or history of cancer
- xPregnancy or breastfeeding
- xPituitary disorders or tumors
- xKnown allergy to peptide components
- xChildren and adolescents (growth plates still open)
Decision Guide
Which is
right for you?
Choose CJC-1295 with DAC if...
- Boosting natural growth hormone production
- Building lean muscle mass
- Improving body composition
- Anti-aging and longevity
Choose Ipamorelin if...
- Muscle recovery and growth
- Anti-aging and vitality
- Body composition improvement
- Sleep quality enhancement