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Peptide Database

Goals
Fat LossMuscle BuildingInjury HealingAnti-AgingCognitive EnhancementSleep OptimizationImmune SupportGut HealingSkin RejuvenationSexual Health
Peptides
5-Amino-1MQ
Weight Management
Abarelix
Hormone Support
Acetyl Hexapeptide-3 (Argireline)
Cosmetic
Adipotide
Weight Management
Adrenomedullin
Healing & Recovery
Alexamorelin
Growth Hormone
Angiotensin (1-7)
Healing & Recovery
AOD-9604
Weight Management
Apelin-13
Healing & Recovery
ARA-290 (Cibinetide)
Healing & Recovery
Bestatin (Ubenimex)
Immune
BPC-157
Healing & Recovery
Buserelin
Hormone Support
Cagrilintide
Weight Management
CagriSema
Weight Management
Capromorelin
Growth Hormone
Cartalax
Anti-Aging
Cathelicidin (hCAP-18 / Synthetic Derivatives)
Immune
Cerebrolysin
Cognitive
Cerluten
Cognitive
Cetrorelix
Hormone Support
Chonluten
Immune
CJC-1295 (No DAC)
Growth Hormone
CJC-1295 with DAC
Growth Hormone
Cortexin
Cognitive
Crystagen
Immune
Daptomycin
Immune
Defensin (HBD-2)
Immune
Defensin (HBD-3)
Immune
Degarelix
Hormone Support
Dihexa
Cognitive
DSIP (Delta Sleep-Inducing Peptide)
Sleep & Recovery
Dulaglutide
Weight Management
Enalapril
Healing & Recovery
Epithalon
Anti-Aging
Exenatide
Weight Management
Fertirelin
Hormone Support
FOXO4-DRI
Anti-Aging
Ganirelix
Hormone Support
GHK-Cu (Copper Peptide)
Cosmetic
GHRH (1-29)
Growth Hormone
GHRP-2
Growth Hormone
GHRP-6 (Growth Hormone Releasing Peptide-6)
Growth Hormone
Glutathione
Anti-Aging
Gonadorelin (GnRH)
Hormone Support
Gramicidin
Immune
Hexarelin
Growth Hormone
Human Chorionic Gonadotropin (HCG)
Hormone Support
Human Growth Hormone (HGH)
Growth Hormone
IGF-1 LR3
Growth Hormone
Immunoxel (Dzherelo)
Immune
Imunofan
Immune
Intermedin (Adrenomedullin-2)
Healing & Recovery
Ipamorelin
Growth Hormone
Kisspeptin-10
Sexual Health
KPV (Alpha-MSH Fragment)
Healing & Recovery
Lactoferricin B
Immune
Larazotide
Healing & Recovery
Lentinan
Immune
Leuphasyl
Cosmetic
Leuprolide
Hormone Support
Liraglutide
Weight Management
Livagen
Anti-Aging
Lixisenatide
Weight Management
LL-37
Immune
Macimorelin
Growth Hormone
Magainin-2
Immune
Mazdutide
Weight Management
Melanotan-2
Cosmetic
MK-677 (Ibutamoren)
Growth Hormone
MOTS-c
Metabolic
Myristoyl Pentapeptide-17
Cosmetic
N-Acetyl Selank
Cognitive
N-Acetyl Semax Amidate
Cognitive
NAD+
Mitochondrial
Nafarelin
Hormone Support
Natriuretic Peptide (ANP)
Healing & Recovery
Nesiritide (BNP)
Healing & Recovery
Nisin
Immune
Noopept (Omberacetam)
Cognitive
Orforglipron
Weight Management
Ovagen
Anti-Aging
Oxytocin Acetate
Hormone Support
P21 (P021)
Cognitive
PACAP-38
Healing & Recovery
Palmitoyl Oligopeptide
Cosmetic
Palmitoyl Pentapeptide-4 (Matrixyl)
Cosmetic
Palmitoyl Tetrapeptide-7
Cosmetic
Palmitoyl Tripeptide-1
Cosmetic
Pancragen
Metabolic
PEG-MGF
Healing & Recovery
Pemvidutide
Weight Management
Pentadecapeptide (BPC Analog)
Healing & Recovery
Pidotimod
Immune
Pinealon
Cognitive
PNC-27
Immune
Polymyxin B
Immune
Pralmorelin (GHRP-2)
Growth Hormone
Pramlintide
Weight Management
Prostamax
Hormone Support
PT-141 (Bremelanotide)
Sexual Health
Relaxin-2 (Serelaxin)
Healing & Recovery
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Setmelanotide
Weight Management
SLU-PP-332
Metabolic
SM-130686
Growth Hormone
Snap-8
Cosmetic
SS-31 (Elamipretide)
Mitochondrial
Substance P Antagonists
Healing & Recovery
Survodutide
Weight Management
SYN-AKE
Cosmetic
Tabimorelin
Growth Hormone
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Testagen
Hormone Support
Thymalin
Immune
Thymopentin (TP-5)
Immune
Thymopoietin
Immune
Thymosin Alpha-1
Immune
Thymosin Beta-4
Healing & Recovery
Thymulin (FTS)
Immune
Thymulin Analog (PAT)
Healing & Recovery
Tirzepatide
Weight Management
Tripeptide-29
Cosmetic
Triptorelin
Hormone Support
Ularitide
Healing & Recovery
Urocortin
Healing & Recovery
Ventfort
Anti-Aging
Vesilute
Hormone Support
Vilon
Immune
VIP (Vasoactive Intestinal Peptide)
Healing & Recovery
Xenin-25
Metabolic
Ziconotide (Prialt)
Healing & Recovery
Total Peptides: 137
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Condition Spotlight

Adult Growth
Hormone Deficiency

Growth hormone isn't just for growing. In adults, it's essential for maintaining muscle mass, bone density, energy levels, and overall vitality. When your GH levels drop - whether from pituitary problems, head trauma, or simply age - you feel it in every aspect of your life.

Written by Michael Carroll — Owner, Director of Research · Reviewed by the Peptide Initiative Research Team · Editorial standards

The Problem

Your Body's Repair
System Is Running Low

Low Energy

Persistent fatigue that rest doesn't fix

Body Changes

Muscle loss and increasing belly fat

Cognitive Fog

Difficulty concentrating and poor memory

Understanding GH Deficiency

The Master Hormone You're Missing

Growth hormone, released by your pituitary gland, does far more than regulate height. It's a metabolic regulator that affects virtually every tissue in your body. GH stimulates protein synthesis, promotes fat breakdown, supports bone density, enhances immune function, and even affects mood and cognitive function. In adults, GH deficiency can result from pituitary tumors, surgery, radiation, head trauma, or other conditions affecting the pituitary. It also occurs naturally with age - GH production drops approximately 14% per decade after age 30, a phenomenon called somatopause.

"Your body's repair and regeneration capacity depends on adequate growth hormone."

The symptoms of GH deficiency are often vague and overlap with other conditions: fatigue, reduced muscle mass, increased body fat (especially around the midsection), poor exercise capacity, depression, and reduced quality of life. Peptide therapies offer a way to stimulate your body's natural GH production rather than simply replacing the hormone.

The Solutions

6 Peptides
6 Angles of Attack

1980s

Sermorelin

The Established Choice

A synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates your pituitary to release its own GH. FDA-approved for diagnostic testing and pediatric use.

Role

Asking your pituitary to wake up and do its job

2005

CJC-1295

The Long-Acting GHRH

A modified GHRH analog with extended half-life. Available with or without DAC (Drug Affinity Complex) which further extends duration.

Role

A slow-release version of the signal that tells your pituitary to release GH

1998

Ipamorelin

The Selective GHRP

A growth hormone-releasing peptide (GHRP) that stimulates GH release through the ghrelin receptor, with high selectivity and minimal side effects.

Role

A precise signal that triggers GH release without unwanted noise

1994

GHRP-2

The Potent GHRP

A growth hormone-releasing peptide with strong GH-stimulating effects. More potent than ipamorelin but with more side effects.

Role

A louder signal for GH release - effective but less selective

1984

GHRP-6

The Hunger-Inducing GHRP

A growth hormone-releasing peptide that strongly stimulates GH and also significantly increases appetite through ghrelin receptor activation.

Role

A powerful GH signal that also tells your brain you're hungry

1990s

MK-677 (Ibutamoren)

The Oral Option

An oral growth hormone secretagogue that stimulates GH release through the ghrelin receptor. Not a peptide technically, but commonly discussed alongside GH peptides.

Role

An oral pill that mimics the effects of injectable GH-releasing peptides

The Strategy

How They Work Together
Together

PeptidePrimary RoleAnalogy
Sermorelin

The Established Choice

Asking your pituitary to wake up and do its job

CJC-1295

The Long-Acting GHRH

A slow-release version of the signal that tells your pituitary to release GH

Ipamorelin

The Selective GHRP

A precise signal that triggers GH release without unwanted noise

GHRP-2

The Potent GHRP

A louder signal for GH release - effective but less selective

GHRP-6

The Hunger-Inducing GHRP

A powerful GH signal that also tells your brain you're hungry

MK-677 (Ibutamoren)

The Oral Option

An oral pill that mimics the effects of injectable GH-releasing peptides

6 Angles of Attack

GHRH Pathway

Sermorelin, CJC-1295, and tesamorelin work by mimicking GHRH, the natural signal for GH release

Ghrelin Pathway

Ipamorelin, GHRP-2, GHRP-6, and MK-677 work through the ghrelin receptor to amplify GH release

Synergistic Effect

Combining GHRH + GHRP produces greater GH release than either alone (1+1=3 effect)

Timing Matters

Bedtime dosing enhances the natural nocturnal GH surge for maximum effect

Important Considerations

Reality Check
What to Keep in Mind

Not for Cancer History

GH and IGF-1 promote cell growth. People with active cancer or certain cancer histories should not use GH peptides. Thorough medical evaluation is essential before starting.

Research Peptides

Most GH peptides (except tesamorelin) are not FDA-approved for GH deficiency. Quality varies significantly by source. Work with reputable providers and medical supervision.

Medical Supervision Required

GH peptide therapy should be medically supervised with regular monitoring of IGF-1, glucose, and other parameters. This isn't appropriate for self-experimentation.

This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before starting any new treatment.

Realistic Expectations

What to Expect: A Realistic Timeline

An honest breakdown based on research and clinical reports.

What's Happening Inside

Your body is beginning to respond to GH stimulation. IGF-1 levels are starting to rise. Most people don't notice dramatic changes yet.

What You Might Notice

  • Possibly improved sleep quality - often an early sign
  • Some people notice vivid dreams
  • Subtle increase in energy for some
  • Establishing injection routine

Watch For

Minor water retention or joint stiffness can occur as GH levels rise. This is usually temporary and indicates the peptide is working.

Realistic Expectations

Focus on establishing routine. Don't expect dramatic changes yet.

Administration Guide

Dosing Protocols & Timing

General guidelines based on research literature and clinical reports. Work with a healthcare provider experienced in peptide therapy to customize for your situation.

Important: These are general guidelines. Don't self-prescribe based on internet articles. Work with a qualified healthcare provider.

Sermorelin

0.1-1 mg per injection

Common Protocols

  • Starting dose: 200-300 mcg subcutaneous before bed
  • Maintenance: 300-500 mcg daily
  • Some protocols use twice-daily dosing for enhanced effect

Timing Considerations

  • Evening injection 30-60 minutes before bed is preferred
  • Can be dosed on empty stomach or with food
  • Consistent daily timing supports better pituitary responsiveness

Cycling

Often used for 8-12 weeks, though some use continuously

Beyond Peptides

Lifestyle Strategies for Living Well

Peptides work best as part of a comprehensive approach. Click each category to explore evidence-based strategies.

At a Glance

Quick Reference Card

Peptide Overview

PeptideWhat It DoesTypical DoseTiming
Sermorelin
The Established Choice0.1-1 mg per injectionEvening injection 30-60 minutes before bed is preferred
CJC-1295
The Long-Acting GHRH100-200 mcg per injectionIdeally administered 30-60 minutes before exercise for synergistic effect
Ipamorelin
The Selective GHRP200-400 mcg per injectionMorning and evening dosing is typical to maintain elevated GH throughout the day
GHRP-2
The Potent GHRP100-300 mcg per injectionEvening injection (30-90 minutes before bed) most effective
GHRP-6
The Hunger-Inducing GHRP100-300 mcg per injectionEvening injection 30-90 minutes before bed is standard
MK-677 (Ibutamoren)
The Oral Option10-25 mg per dayEvening dosing (30-90 minutes before bed) most popular

Early Wins to Watch

  • Improved sleep quality
  • Better recovery from exercise
  • Increased energy levels
  • Improved mood

Support Stack

Adequate protein intakeQuality sleep (7-9 hours)Resistance trainingStress managementAvoiding food before dosing

Lifestyle Priorities

  • Prioritize sleep quality
  • Regular resistance training
  • Adequate protein intake
  • Dose on empty stomach
  • Regular lab monitoring

Growth hormone peptide therapy can help restore vitality, improve body composition, and enhance quality of life in adults with GH deficiency or age-related decline. These are powerful tools that work best when combined with the lifestyle factors that support natural GH function.

Work with a healthcare provider experienced in hormone optimization. Regular monitoring ensures safety and allows dose adjustment for optimal results.