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Peptide Database

Goals
Fat LossMuscle BuildingInjury HealingAnti-AgingCognitive EnhancementSleep OptimizationImmune SupportGut HealingSkin RejuvenationSexual Health
Peptides
5-Amino-1MQ
Weight Management
Abarelix
Hormone Support
Acetyl Hexapeptide-3 (Argireline)
Cosmetic
Adipotide
Weight Management
Adrenomedullin
Healing & Recovery
Alexamorelin
Growth Hormone
Angiotensin (1-7)
Healing & Recovery
AOD-9604
Weight Management
Apelin-13
Healing & Recovery
ARA-290 (Cibinetide)
Healing & Recovery
Bestatin (Ubenimex)
Immune
BPC-157
Healing & Recovery
Buserelin
Hormone Support
Cagrilintide
Weight Management
CagriSema
Weight Management
Capromorelin
Growth Hormone
Cartalax
Anti-Aging
Cathelicidin (hCAP-18 / Synthetic Derivatives)
Immune
Cerebrolysin
Cognitive
Cerluten
Cognitive
Cetrorelix
Hormone Support
Chonluten
Immune
CJC-1295 (No DAC)
Growth Hormone
CJC-1295 with DAC
Growth Hormone
Cortexin
Cognitive
Crystagen
Immune
Daptomycin
Immune
Defensin (HBD-2)
Immune
Defensin (HBD-3)
Immune
Degarelix
Hormone Support
Dihexa
Cognitive
DSIP (Delta Sleep-Inducing Peptide)
Sleep & Recovery
Dulaglutide
Weight Management
Enalapril
Healing & Recovery
Epithalon
Anti-Aging
Exenatide
Weight Management
Fertirelin
Hormone Support
FOXO4-DRI
Anti-Aging
Ganirelix
Hormone Support
GHK-Cu (Copper Peptide)
Cosmetic
GHRH (1-29)
Growth Hormone
GHRP-2
Growth Hormone
GHRP-6 (Growth Hormone Releasing Peptide-6)
Growth Hormone
Glutathione
Anti-Aging
Gonadorelin (GnRH)
Hormone Support
Gramicidin
Immune
Hexarelin
Growth Hormone
Human Chorionic Gonadotropin (HCG)
Hormone Support
Human Growth Hormone (HGH)
Growth Hormone
IGF-1 LR3
Growth Hormone
Immunoxel (Dzherelo)
Immune
Imunofan
Immune
Intermedin (Adrenomedullin-2)
Healing & Recovery
Ipamorelin
Growth Hormone
Kisspeptin-10
Sexual Health
KPV (Alpha-MSH Fragment)
Healing & Recovery
Lactoferricin B
Immune
Larazotide
Healing & Recovery
Lentinan
Immune
Leuphasyl
Cosmetic
Leuprolide
Hormone Support
Liraglutide
Weight Management
Livagen
Anti-Aging
Lixisenatide
Weight Management
LL-37
Immune
Macimorelin
Growth Hormone
Magainin-2
Immune
Mazdutide
Weight Management
Melanotan-2
Cosmetic
MK-677 (Ibutamoren)
Growth Hormone
MOTS-c
Metabolic
Myristoyl Pentapeptide-17
Cosmetic
N-Acetyl Selank
Cognitive
N-Acetyl Semax Amidate
Cognitive
NAD+
Mitochondrial
Nafarelin
Hormone Support
Natriuretic Peptide (ANP)
Healing & Recovery
Nesiritide (BNP)
Healing & Recovery
Nisin
Immune
Noopept (Omberacetam)
Cognitive
Orforglipron
Weight Management
Ovagen
Anti-Aging
Oxytocin Acetate
Hormone Support
P21 (P021)
Cognitive
PACAP-38
Healing & Recovery
Palmitoyl Oligopeptide
Cosmetic
Palmitoyl Pentapeptide-4 (Matrixyl)
Cosmetic
Palmitoyl Tetrapeptide-7
Cosmetic
Palmitoyl Tripeptide-1
Cosmetic
Pancragen
Metabolic
PEG-MGF
Healing & Recovery
Pemvidutide
Weight Management
Pentadecapeptide (BPC Analog)
Healing & Recovery
Pidotimod
Immune
Pinealon
Cognitive
PNC-27
Immune
Polymyxin B
Immune
Pralmorelin (GHRP-2)
Growth Hormone
Pramlintide
Weight Management
Prostamax
Hormone Support
PT-141 (Bremelanotide)
Sexual Health
Relaxin-2 (Serelaxin)
Healing & Recovery
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Setmelanotide
Weight Management
SLU-PP-332
Metabolic
SM-130686
Growth Hormone
Snap-8
Cosmetic
SS-31 (Elamipretide)
Mitochondrial
Substance P Antagonists
Healing & Recovery
Survodutide
Weight Management
SYN-AKE
Cosmetic
Tabimorelin
Growth Hormone
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Testagen
Hormone Support
Thymalin
Immune
Thymopentin (TP-5)
Immune
Thymopoietin
Immune
Thymosin Alpha-1
Immune
Thymosin Beta-4
Healing & Recovery
Thymulin (FTS)
Immune
Thymulin Analog (PAT)
Healing & Recovery
Tirzepatide
Weight Management
Tripeptide-29
Cosmetic
Triptorelin
Hormone Support
Ularitide
Healing & Recovery
Urocortin
Healing & Recovery
Ventfort
Anti-Aging
Vesilute
Hormone Support
Vilon
Immune
VIP (Vasoactive Intestinal Peptide)
Healing & Recovery
Xenin-25
Metabolic
Ziconotide (Prialt)
Healing & Recovery
Total Peptides: 137
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Condition Spotlight

Growth Hormone
Decline

Starting at age 30, your body's growth hormone production drops about 14% per decade. This isn't just about aging gracefully - it's about declining muscle, increasing fat, poor sleep, and looking in the mirror seeing someone older than you feel you should be. This is called somatopause, and it's treatable.

Written by Michael Carroll — Owner, Director of Research · Reviewed by the Peptide Initiative Research Team · Editorial standards

The Problem

Your Body's Anabolic Fuel
Is Quietly Running Out

Declining Muscle

Strength fades even with the same training

Increasing Fat

Body composition shifts toward fat storage

Poor Sleep Quality

Less deep sleep, more fragmented nights

Aged Appearance

Skin loses elasticity and luminosity

Understanding Growth Hormone

The Master Hormone of Youth

Growth hormone (GH) is secreted by your pituitary gland and is responsible for anabolic effects throughout your body - building and maintaining muscle, burning fat, maintaining skin elasticity, supporting deep restorative sleep, and preserving cognitive function. When you're young, your pituitary releases GH in distinct pulses, especially during deep sleep. This stimulates your liver to produce IGF-1 (insulin-like growth factor-1), which is the actual workhorse that builds tissue. But after age 30, something happens. The amplitude and frequency of those pulses decline. By age 50-60, many people have lost 50% or more of their GH secretion. Your body keeps working, but at half capacity.

"At age 40, most people have half the growth hormone they had at age 20."

The result? Your muscles don't recover as well from training. Your body preferentially stores fat instead of building muscle. Your skin loses its youthful glow. Your sleep becomes fragmented. You age faster at the cellular level. This is where GH-releasing peptides come in - they're like coaching your pituitary back into its younger pattern of hormone release.

The Solutions

7 Peptides
7 Angles of Attack

2005

CJC-1295

The Long-Acting Growth Hormone Booster

A synthetic GH-releasing hormone analog that stimulates the pituitary to produce and release more growth hormone. Available with DAC (drug affinity complex) for extended duration.

Role

Coaching your pituitary back to its younger pattern

1998

Ipamorelin

The Selective GH Stimulator

A selective GH secretagogue that stimulates GH release without significantly affecting cortisol or prolactin - making it one of the cleanest GH-releasing peptides.

Role

Precise surgical strike on your pituitary

1994

GHRP-2

The Potent GH Pulse Generator

A growth hormone-releasing peptide that strongly stimulates GH release and mimics the body's natural ghrelin signaling. Potent but comes with more side effects than some alternatives.

Role

Turning up the volume on GH signaling

1984

GHRP-6

The Appetite-Stimulating GH Releaser

Similar mechanism to GHRP-2 but with even stronger appetite stimulation. Preferred by those specifically looking to increase food intake for muscle building.

Role

Turning hunger into a feature, not a bug

1980s

Sermorelin

The Physiologic GH-Releasing Hormone

A synthetic version of GH-releasing hormone (GHRH) - essentially the body's natural command to release GH. Works at the pituitary level to stimulate endogenous GH production.

Role

Reminding your body to do what it already knows how to do

Approved 2010

Tesamorelin

The Visceral Fat Reduction Specialist

A modified GHRH analog specifically studied for its ability to reduce visceral adiposity. FDA-approved for HIV-related lipodystrophy, increasingly used off-label for age-related fat redistribution.

Role

Targeting belly fat with surgical precision

1990s

MK-677 (Ibutamoren)

The Oral GH Secretagogue

A non-peptide oral ghrelin receptor agonist (not technically a peptide, but often grouped with them). Taken as a pill rather than injection - unique among GH secretagogues.

Role

GH stimulation without the needle

The Strategy

How They Work Together
Together

PeptidePrimary RoleAnalogy
CJC-1295

The Long-Acting Growth Hormone Booster

Coaching your pituitary back to its younger pattern

Ipamorelin

The Selective GH Stimulator

Precise surgical strike on your pituitary

GHRP-2

The Potent GH Pulse Generator

Turning up the volume on GH signaling

GHRP-6

The Appetite-Stimulating GH Releaser

Turning hunger into a feature, not a bug

Sermorelin

The Physiologic GH-Releasing Hormone

Reminding your body to do what it already knows how to do

Tesamorelin

The Visceral Fat Reduction Specialist

Targeting belly fat with surgical precision

MK-677 (Ibutamoren)

The Oral GH Secretagogue

GH stimulation without the needle

7 Angles of Attack

Sustained Elevation

CJC-1295 with DAC provides baseline GH elevation, creating a steady foundation

Pulsatile Stimulation

Secretagogues like Ipamorelin and GHRP-2 add episodic pulses on top of baseline elevation

Physiologic Support

Sermorelin works with natural biology to promote endogenous GH production

Fat Loss Specialization

Tesamorelin provides targeted visceral fat reduction alongside general GH benefits

Important Considerations

Reality Check
What to Keep in Mind

Peptides Amplify, Don't Replace

Peptides support GH/IGF-1 restoration, but you still need to train hard and eat well. They multiply your effort, not replace it.

Individual Response Varies

Some people respond dramatically. Others see modest benefits. Genetics, age, baseline fitness, and lifestyle all affect outcomes.

Professional Guidance Matters

Work with a healthcare provider experienced in peptide therapy. Proper dosing, monitoring, and protocol design matter for safety and efficacy.

IGF-1 Monitoring Important

Check baseline IGF-1 levels before starting and periodically during use. Aim for the upper half of the normal range for age, not excessively high.

This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before starting any new treatment.

Realistic Expectations

What to Expect: A Realistic Timeline

An honest breakdown based on research and clinical reports.

What's Happening Inside

Peptides are beginning to stimulate your pituitary. GH and IGF-1 levels are starting to rise. Your body is adjusting to increased hormone signaling.

What You Might Notice

  • Sleep quality often improves immediately - deeper sleep, less fragmentation
  • Appetite may increase (especially with GHRP-2, GHRP-6, or MK-677)
  • Some users notice increased energy or mood lift
  • Possible mild water retention as GH increases (normal and temporary)
  • Joint aches may improve as GH supports connective tissue

Watch For

Some users experience brief carpal tunnel-like symptoms or joint stiffness as connective tissue remodels. This typically resolves. Mild water retention is normal.

Realistic Expectations

The first changes are usually subjective - sleep and energy. Don't expect visible body composition changes yet.

Administration Guide

Dosing Protocols & Timing

General guidelines based on research literature and clinical reports. Work with a healthcare provider experienced in peptide therapy to customize for your situation.

Important: These are general guidelines. Don't self-prescribe based on internet articles. Work with a qualified healthcare provider.

CJC-1295

100-200 mcg per injection

Common Protocols

  • Conservative: 100 mcg two times per week
  • Standard: 150 mcg two times per week (most common)
  • Higher: 200-300 mcg two times per week
  • CJC-1295 with DAC: 200-300 mcg once every 5-7 days (longer acting)

Timing Considerations

  • Ideally administered 30-60 minutes before exercise for synergistic effect
  • Evening dosing (1-2 hours before sleep) aligns with natural GH surge during sleep
  • Morning dosing also acceptable for convenience
  • Avoid food 30 minutes before and after injection (insulin antagonistic to GH)

Cycling

8-16 weeks on, 2-4 weeks off, or continuous protocols depending on goals

Beyond Peptides

Lifestyle Strategies for Living Well

Peptides work best as part of a comprehensive approach. Click each category to explore evidence-based strategies.

At a Glance

Quick Reference Card

Peptide Overview

PeptideWhat It DoesTypical DoseTiming
CJC-1295
The Long-Acting Growth Hormone Booster100-200 mcg per injectionIdeally administered 30-60 minutes before exercise for synergistic effect
Ipamorelin
The Selective GH Stimulator200-400 mcg per injectionMorning and evening dosing is typical to maintain elevated GH throughout the day
GHRP-2
The Potent GH Pulse Generator100-300 mcg per injectionEvening injection (30-90 minutes before bed) most effective
GHRP-6
The Appetite-Stimulating GH Releaser100-300 mcg per injectionEvening injection 30-90 minutes before bed is standard
Sermorelin
The Physiologic GH-Releasing Hormone0.1-1 mg per injectionEvening injection 30-60 minutes before bed is preferred
Tesamorelin
The Visceral Fat Reduction Specialist0.1-0.2 mg dailyEvening injection (before bed) aligns with natural GH surge during sleep
MK-677 (Ibutamoren)
The Oral GH Secretagogue10-25 mg per dayEvening dosing (30-90 minutes before bed) most popular

Early Wins to Watch

  • Improved sleep quality (week 1)
  • Better recovery from training (week 2-3)
  • Improved skin appearance (week 3-4)
  • Noticeable strength improvements (week 4-6)

Support Stack

Whey protein powderCreatine monohydrateOmega-3 fish oilVitamin D3MagnesiumZincBeta-alanine

Lifestyle Priorities

  • Progressive resistance training 3-5x weekly
  • Adequate protein intake (0.8-1g per lb body weight)
  • 7-9 hours of sleep nightly
  • Stress management and recovery focus
  • Consistent meal timing and composition

Growth hormone decline is not just about aging - it's about losing your capacity to build, recover, and thrive. Restoring GH through peptides addresses this at the root. Combined with training and nutrition, you can look 5-10 years younger and feel substantially better. This isn't anti-aging fantasy - it's biology.

Your body knows how to be young. Sometimes it just needs the right signal to remember.