Peptide Comparison
AlexamorelinvsCJC-1295 (No DAC)
A next-generation growth hormone releaser that converts to hexarelin in your body for enhanced GH, cortisol, and unique aldosterone stimulation.
A modified growth hormone-releasing hormone that boosts your body's natural GH pulses for better recovery, deeper sleep, and improved body composition.
At a Glance
Quick
comparison
Dose Range
Alexamorelin
100–300 mcg
CJC-1295 (No DAC)
100–300 mcg
Frequency
Alexamorelin
Multiple times daily
CJC-1295 (No DAC)
Once daily
Administration
Alexamorelin
Subcutaneous injection
CJC-1295 (No DAC)
Subcutaneous injection
Cycle Length
Alexamorelin
4-6 weeks
CJC-1295 (No DAC)
8-12 weeks
Onset Speed
Alexamorelin
Moderate (1-2 weeks)
CJC-1295 (No DAC)
Moderate (1-2 weeks)
Evidence Level
Alexamorelin
Limited human trials
CJC-1295 (No DAC)
Moderate human trials (Phase 1-2)
Efficacy
Benefit
ratings
Growth Hormone Release
Hormone Axis Stimulation
Research & Innovation
GH Stimulation
Sleep Quality
Recovery Support
Technical Data
Compound
specifications
Alexamorelin
Molecular Formula
C50H63N13O7
Molecular Weight
958.1 g/mol
Half-Life
Estimated 1-3 hours (rapidly metabolized to hexarelin)
Bioavailability
Active IV and orally; subcutaneous bioavailability expected moderate to good
CAS Number
196808-85-2
CJC-1295 (No DAC)
Molecular Formula
C152H252N44O42
Molecular Weight
3367.9 g/mol
Half-Life
30 minutes to 2 hours
Bioavailability
~100% (subcutaneous)
CAS Number
863288-34-0
Protocols
Dosing
tiers
Alexamorelin
CJC-1295 (No DAC)
Applications
Best
suited for
Alexamorelin
Muscle Builders and Athletes
Alexamorelin's potent GH release makes it ideal for those serious about muscle gains. Its stronger ACTH response compared to hexarelin provides additional recovery benefits, though the cortisol elevation requires monitoring. The oral option is convenient for athletes avoiding injections, though subcutaneous injection remains most practical.
Research-Focused Peptide Users
If you're exploring next-generation GHS compounds, alexamorelin offers a fascinating case study: it's a prodrug that becomes hexarelin in your body, offering a unique window into peptide metabolism. This makes it valuable for understanding how compound modifications affect potency and half-life.
Synergistic Stack Enthusiasts
Alexamorelin shines when stacked with GHRH, creating synergistic GH release that exceeds either alone. It also pairs well with recovery-focused peptides like BPC-157, making it the centerpiece of comprehensive growth protocols.
CJC-1295 (No DAC)
Natural Growth Hormone Optimization
Perfect for those wanting to boost their body's own GH production rather than using synthetic growth hormone. Mimics the natural pulsatile release pattern your pituitary uses.
Workout Recovery and Muscle Building
Athletes and fitness enthusiasts use it to accelerate recovery between training sessions, support lean muscle development, and reduce body fat over time.
Sleep Quality Enhancement
Because GH is naturally released during deep sleep, many users report dramatically improved sleep quality with more vivid dreams and feeling more refreshed upon waking.
Anti-Aging and Vitality
As GH levels decline with age, CJC-1295 helps restore more youthful hormone patterns, potentially improving skin quality, energy levels, and overall well-being.
Synergistic Peptide Stacking
Designed to work hand-in-hand with GHRPs like Ipamorelin. When combined, these peptides amplify each other's effects for significantly greater GH release than either alone.
Safety Profile
Side
effects
Alexamorelin
Common
- Increased Hunger
- Water Retention
- Injection Site Reactions
Uncommon
- Cortisol-Related Mood Changes
- Joint or Muscle Aches
Serious
- Allergic Reaction
CJC-1295 (No DAC)
Common
- Injection site reactions
- Flushing or warmth
- Water retention
- Increased appetite
Uncommon
- Tingling or numbness
- Headache
Serious
- Allergic reaction
Research Status
Safety
& evidence
Alexamorelin
Evidence Level
Limited human trials
FDA Status
Research compound
Safety Overview
Alexamorelin is a research compound with only one small human study (6 subjects), making it much less proven than hexarelin. While it shows promise as a potent GH releaser, the limited human evidence means we don't fully understand long-term effects, optimal dosing in different populations, or rare side effects. Its unique stronger ACTH and aldosterone effects require careful monitoring. Always start low and monitor how your body responds.
Contraindications
- xActive malignancy or cancer history (GH stimulation concern)
- xUncontrolled diabetes or severe glucose dysregulation
- xSevere cardiovascular disease or unmanaged hypertension
- xPregnancy or nursing
CJC-1295 (No DAC)
Evidence Level
Moderate human trials (Phase 1-2)
FDA Status
Research compound
Safety Overview
CJC-1295 without DAC has been studied in Phase 1-2 human clinical trials with a favorable safety profile. The most common side effects are mild and include injection site reactions and temporary flushing. Because it stimulates natural GH release rather than providing exogenous GH, it maintains the body's feedback mechanisms.
Contraindications
- xActive cancer or history of cancer
- xPregnancy or breastfeeding
- xPituitary tumors or disorders
- xHypersensitivity to GHRH analogs
- xDiabetic retinopathy
Decision Guide
Which is
right for you?
Choose Alexamorelin if...
- Maximizing growth hormone release for muscle building
- Cycling with other peptides for synergistic GH stack effects
- Research into next-generation GHS compounds
- Understanding prodrug metabolism in peptide design
Choose CJC-1295 (No DAC) if...
- Increasing natural growth hormone levels
- Building lean muscle mass
- Improving sleep quality
- Enhancing workout recovery