Pramlintide Dosing Calculator
Vial size, bacteriostatic water, and dose — converted to insulin-syringe units, pre-loaded with Pramlintide's documented doses.
Typical dose: 15 mcg per meal (type 1 diabetes), titrated to 60 mcg per meal, titrating to 120 mcg (type 2 diabetes) · immediately before each major meal
Pramlintide documented dose levels
| Phase | Dose | Frequency |
|---|---|---|
| Titrate up after 3+ days without significant nausea | 15 mcg per meal (type 1 diabetes) | Immediately before each major meal |
| Ongoing, as tolerated | 30-60 mcg per meal (type 1 diabetes) | Immediately before each major meal |
| Increase to 120 mcg after 3+ days without significant nausea | 60 mcg per meal, titrating to 120 mcg (type 2 diabetes) | Immediately before each major meal |
Reconstitution quick reference
A 5 mg vial at a 45 mcg dose of Pramlintide, by how much bacteriostatic water you add:
| Bacteriostatic water | Concentration | U-100 syringe units per dose |
|---|---|---|
| 1 mL | 5 mg/mL | 0.9 units |
| 2 mL | 2.5 mg/mL | 1.8 units |
| 3 mL | 1.667 mg/mL | 2.7 units |
Different vial size or dose? The calculator above handles any combination.
Pramlintide dosing questions
What is a typical Pramlintide dose?
15 mcg per meal (type 1 diabetes), titrated to 60 mcg per meal, titrating to 120 mcg (type 2 diabetes) · immediately before each major meal
How many insulin-syringe units is a Pramlintide dose?
With a 5 mg vial reconstituted with 2 mL of bacteriostatic water, a 45 mcg dose measures 1.8 units on a U-100 insulin syringe. The calculator above recomputes this for your own vial size, water volume, and dose.
How often is Pramlintide taken?
Immediately before each major meal
Educational information only — not medical advice. Always consult a qualified healthcare provider.