Orforglipron Dosing Calculator
Vial size, bacteriostatic water, and dose — converted to insulin-syringe units, pre-loaded with Orforglipron's documented doses.
Typical dose: 6 mg once daily, titrated to 36 mg once daily · once daily, any time of day
Orforglipron documented dose levels
| Phase | Dose | Frequency |
|---|---|---|
| Lowest of three phase-3 maintenance doses | 6 mg once daily | Once daily, any time of day |
| Maintained for 72-week trial duration | 12 mg once daily | Once daily, any time of day |
| Maintained for 72-week trial duration | 36 mg once daily | Once daily, any time of day |
Reconstitution quick reference
A 5 mg vial at a 12,000 mcg dose of Orforglipron, by how much bacteriostatic water you add:
| Bacteriostatic water | Concentration | U-100 syringe units per dose |
|---|---|---|
| 1 mL | 5 mg/mL | 240 units |
| 2 mL | 2.5 mg/mL | 480 units |
| 3 mL | 1.667 mg/mL | 720 units |
Different vial size or dose? The calculator above handles any combination.
Orforglipron dosing questions
What is a typical Orforglipron dose?
6 mg once daily, titrated to 36 mg once daily · once daily, any time of day
How many insulin-syringe units is a Orforglipron dose?
With a 5 mg vial reconstituted with 2 mL of bacteriostatic water, a 12,000 mcg dose measures 480 units on a U-100 insulin syringe. The calculator above recomputes this for your own vial size, water volume, and dose.
How often is Orforglipron taken?
Once daily, any time of day
Educational information only — not medical advice. Always consult a qualified healthcare provider.