Eagle LogoPEPTIDE INITIATIVE

Peptide Database

Goals
Fat LossMuscle BuildingInjury HealingAnti-AgingCognitive EnhancementSleep OptimizationImmune SupportGut HealingSkin RejuvenationSexual Health
Peptides
5-Amino-1MQ
Weight Management
Abarelix
Hormone Support
Acetyl Hexapeptide-3 (Argireline)
Cosmetic
Adipotide
Weight Management
Adrenomedullin
Healing & Recovery
Alexamorelin
Growth Hormone
Angiotensin (1-7)
Healing & Recovery
AOD-9604
Weight Management
Apelin-13
Healing & Recovery
ARA-290 (Cibinetide)
Healing & Recovery
Bestatin (Ubenimex)
Immune
BPC-157
Healing & Recovery
Buserelin
Hormone Support
Cagrilintide
Weight Management
CagriSema
Weight Management
Capromorelin
Growth Hormone
Cartalax
Anti-Aging
Cathelicidin (hCAP-18 / Synthetic Derivatives)
Immune
Cerebrolysin
Cognitive
Cerluten
Cognitive
Cetrorelix
Hormone Support
Chonluten
Immune
CJC-1295 (No DAC)
Growth Hormone
CJC-1295 with DAC
Growth Hormone
Cortexin
Cognitive
Crystagen
Immune
Daptomycin
Immune
Defensin (HBD-2)
Immune
Defensin (HBD-3)
Immune
Degarelix
Hormone Support
Dihexa
Cognitive
DSIP (Delta Sleep-Inducing Peptide)
Sleep & Recovery
Dulaglutide
Weight Management
Enalapril
Healing & Recovery
Epithalon
Anti-Aging
Exenatide
Weight Management
Fertirelin
Hormone Support
FOXO4-DRI
Anti-Aging
Ganirelix
Hormone Support
GHK-Cu (Copper Peptide)
Cosmetic
GHRH (1-29)
Growth Hormone
GHRP-2
Growth Hormone
GHRP-6 (Growth Hormone Releasing Peptide-6)
Growth Hormone
Glutathione
Anti-Aging
Gonadorelin (GnRH)
Hormone Support
Gramicidin
Immune
Hexarelin
Growth Hormone
Human Chorionic Gonadotropin (HCG)
Hormone Support
Human Growth Hormone (HGH)
Growth Hormone
IGF-1 LR3
Growth Hormone
Immunoxel (Dzherelo)
Immune
Imunofan
Immune
Intermedin (Adrenomedullin-2)
Healing & Recovery
Ipamorelin
Growth Hormone
Kisspeptin-10
Sexual Health
KPV (Alpha-MSH Fragment)
Healing & Recovery
Lactoferricin B
Immune
Larazotide
Healing & Recovery
Lentinan
Immune
Leuphasyl
Cosmetic
Leuprolide
Hormone Support
Liraglutide
Weight Management
Livagen
Anti-Aging
Lixisenatide
Weight Management
LL-37
Immune
Macimorelin
Growth Hormone
Magainin-2
Immune
Mazdutide
Weight Management
Melanotan-2
Cosmetic
MK-677 (Ibutamoren)
Growth Hormone
MOTS-c
Metabolic
Myristoyl Pentapeptide-17
Cosmetic
N-Acetyl Selank
Cognitive
N-Acetyl Semax Amidate
Cognitive
NAD+
Mitochondrial
Nafarelin
Hormone Support
Natriuretic Peptide (ANP)
Healing & Recovery
Nesiritide (BNP)
Healing & Recovery
Nisin
Immune
Noopept (Omberacetam)
Cognitive
Orforglipron
Weight Management
Ovagen
Anti-Aging
Oxytocin Acetate
Hormone Support
P21 (P021)
Cognitive
PACAP-38
Healing & Recovery
Palmitoyl Oligopeptide
Cosmetic
Palmitoyl Pentapeptide-4 (Matrixyl)
Cosmetic
Palmitoyl Tetrapeptide-7
Cosmetic
Palmitoyl Tripeptide-1
Cosmetic
Pancragen
Metabolic
PEG-MGF
Healing & Recovery
Pemvidutide
Weight Management
Pentadecapeptide (BPC Analog)
Healing & Recovery
Pidotimod
Immune
Pinealon
Cognitive
PNC-27
Immune
Polymyxin B
Immune
Pralmorelin (GHRP-2)
Growth Hormone
Pramlintide
Weight Management
Prostamax
Hormone Support
PT-141 (Bremelanotide)
Sexual Health
Relaxin-2 (Serelaxin)
Healing & Recovery
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Setmelanotide
Weight Management
SLU-PP-332
Metabolic
SM-130686
Growth Hormone
Snap-8
Cosmetic
SS-31 (Elamipretide)
Mitochondrial
Substance P Antagonists
Healing & Recovery
Survodutide
Weight Management
SYN-AKE
Cosmetic
Tabimorelin
Growth Hormone
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Testagen
Hormone Support
Thymalin
Immune
Thymopentin (TP-5)
Immune
Thymopoietin
Immune
Thymosin Alpha-1
Immune
Thymosin Beta-4
Healing & Recovery
Thymulin (FTS)
Immune
Thymulin Analog (PAT)
Healing & Recovery
Tirzepatide
Weight Management
Tripeptide-29
Cosmetic
Triptorelin
Hormone Support
Ularitide
Healing & Recovery
Urocortin
Healing & Recovery
Ventfort
Anti-Aging
Vesilute
Hormone Support
Vilon
Immune
VIP (Vasoactive Intestinal Peptide)
Healing & Recovery
Xenin-25
Metabolic
Ziconotide (Prialt)
Healing & Recovery
Total Peptides: 137
Back to Home
Back to Tirzepatide

Clinical trials

Every registered trial of Tirzepatide

260 studies, 123 still enrolling.

Plain-Language Summary

Plain-language reading of the public trial registries.

In short

  • Tirzepatide has been studied in people a great deal.
  • 260 registered studies in total.
  • 123 are still enrolling people, so this is active research, not just history.

What kind of research

  • 229 studies actually gave the peptide to volunteers and measured what happened. This is the kind of study that can show whether something works.
  • About 90,221 people took part in those.
  • A further 31 studies only looked at records of people already taking it. These are counted separately because nobody was given the peptide for the study, so they cannot prove cause and effect.

How far along it is

  • 89 trials have reached phase 3 or 4 — the large, late-stage trials regulators rely on to approve a drug.
  • 53 have published results in the medical literature that anyone can read.
  • The research spans 54 countries.

A registered trial is a plan, not a result. Registration means a study was declared in advance; it says nothing about whether the peptide worked, and a trial can be registered and then abandoned.

Filter

Showing 260 of 260 trials for Tirzepatide.

  • NCT06180616Phase 2Not Yet Recruiting40 enrolled2026

    Tirzepatide for the Treatment of Concurrent Type 1 Diabetes and Overweight or Obesity

    Royal North Shore Hospital

    Type 1 Diabetes Mellitus · Overweight and Obesity

  • NCT07468552Phase 2Not Yet Recruiting100 enrolled2026

    Trial of Tirzepatide for the Treatment of Cannabis Use Disorder

    National Institute on Drug Abuse (NIDA)

    Cannabis Use Disorder

  • NCT07349641Phase 2Not Yet Recruiting55 enrolled2026

    A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial Cancer

    National Cancer Institute (NCI)

    Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia · FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma

  • NCT07609160Not Yet Recruiting108 enrolled2026

    Effectiveness of Combined GLP-1/GIP Dual Agonist Therapy and Structured Exercise on Skeletal Muscle Morphology, Quality, and Physical Function in Overweight and Obese Individuals

    Acibadem University

    Obesity · Sarcopenia · Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT07782359Phase 1Not Yet Recruiting30 enrolled2026

    Impact of Using a GLP1 on Treatment Related Side Effects of Lung Cancer Patients Receiving Lorlatinib

    University of Chicago

    Lung Cancer

  • NCT07734870Phase 2Not Yet Recruiting20 enrolled2026

    Tirzepatide for Treatment of CCCA

    Johns Hopkins University

    Central Centrifugal Cicatricial Alopecia (CCCA)

  • NCT07715929Phase 4Not Yet Recruiting710 enrolled2026

    Effect of Tirzepatide on Recurrence of Atrial Fibrillation After Catheter Ablation in Obese Patients

    Yunlong Wang

    Atrial Fibrillation · Obesity & Overweight · Catheter Ablation

  • NCT07756359Phase 4Not Yet Recruiting20 enrolled2026

    Tirzepatide for Ileal Pouch-anal Anastomosis (IPAA) and Chronic High Bowel Frequency (I8F-NS-X008)

    University of North Carolina, Chapel Hill

    Pouch, Ileal · Pouches, Ileoanal · Bowel Diseases, Inflammatory

  • NCT07747805Phase 2Not Yet Recruiting30 enrolled2026

    GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD

    The Cleveland Clinic

    COPD · Obesity & Overweight · Sarcopenia

  • NCT07693608Phase 2Enrolling By Invitation45 enrolled2026

    An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use Disorder

    University of Texas Southwestern Medical Center

    Obesity · Methamphetamine Use Disorder · Cocaine Use Disorder · Stimulant Use Disorders

  • NCT07777575Phase 4Not Yet Recruiting150 enrolled2026

    Resistance Training to Prevent Muscle Loss During Treatment With Tirzepatide

    Technical University of Munich

    Obesity (BMI>30)

  • NCT07720466Not Yet Recruiting40 enrolled2026

    Salivary Function and Dental Changes During GLP-1 Therapy

    Bilecik Seyh Edebali Universitesi

    Obesity · Dental Erosion · Saliva Collection · Saliva Altered

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT06732245Phase 2Not Yet Recruiting224 enrolled2026

    Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese

    Biomed Industries, Inc.

    Obesity and Overweight

  • 2026-526200-69-00Ongoing150 enrolled2026

    RESIST-26-HAL-0150-I

    Klinikum der Technischen Universitaet Muenchen (TUM Klinikum)

    Obesity

  • NCT07728318Not Yet Recruiting52 enrolled2026

    Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients

    Akhtar Saeed Medical and Dental College

    Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight

  • NCT07734792Phase 2/3Not Yet Recruiting430 enrolled2026

    Tirzepatide in Thrombectomy-Treated Acute Ischemic Stroke: A Randomized Trial

    yifang zhu

    Acute Ischemic Stroke (AIS)

  • NCT07760532Not Yet Recruiting200 enrolled2026

    Comparing Facial Aging Between Identical Twins With 3D Imaging

    Ponsky Facial Aesthetics And Plastic Surgery, Llc

    Facial Skin Aging · Facial Volume Loss · Wrinkle Appearance

  • NCT07554638Phase 4Recruiting50 enrolled2026

    Incretin Therapies in Obesity-related HFpEF

    Columbia University

    Heart Failure, Diastolic · Heart Failure With Preserved Ejection Fraction · Obesity

  • NCT07671391Phase 2Not Yet Recruiting60 enrolled2026

    A Randomized, Double-blind, Placebo-controlled Study Evaluating the Effect of LAE102 Injection in Combination With Tirzepatide on Body in Obese Participants

    Shanghai Zhongshan Hospital

    Obesity Adult Onset

  • NCT07619989Recruiting24 enrolled2026

    Transcutaneous Auricular Vagus Nerve Stimulation for Poor Weight-Loss Response to Incretin Receptor Agonists

    The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

    Obesity & Overweight

  • NCT07078838Phase 2Not Yet Recruiting40 enrolled2026

    Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer

    UNC Lineberger Comprehensive Cancer Center

    Endometrial Cancer · Endometrial Intraepithelial Neoplasia · Grade 1 Endometrial Endometrioid Carcinoma

  • NCT07630454Phase 4Not Yet Recruiting602 enrolled2026

    Tirzepatide on Atrial Fibrillation Recurrence After Catheter Ablation in Patients With Obesity and HFpEF

    Yunlong Wang

    Atrial Fibrillation · Heart Failure With Preserved Ejection Fraction (HFpEF) · Tirzepatide

  • NCT07298915Phase 3Not Yet Recruiting24 enrolled2026

    The Effect of Exercise and Tirzepatide on Weight and Health Outcomes (EXER-MED)

    University of Virginia

    Obesity & Overweight

  • NCT07191873Phase 4Not Yet Recruiting60 enrolled2026

    Tirzepatide in Idiopathic Intracranial Hypertension Trial

    Duke University

    Idiopathic Intracranial Hypertension (IIH)

  • NCT07671248Phase 3Not Yet Recruiting15 enrolled2026

    Tirzepatide in the Treatment of Cannabis Use Disorder

    McMaster University

    Cannabis Use Disorder, Moderate · Cannabis Use Disorder, Severe

  • NCT07676331Phase 2Not Yet Recruiting168 enrolled2026

    Clinical Study of Local and Systemic Biological Impact of GLP1/GIP-Receptor Agonists in Patients With Breast Cancer: The CLARA Trial

    Universitaire Ziekenhuizen KU Leuven

    Hormone-receptor-positive Breast Cancer · Early Breast Cancer

  • NCT07573163Phase 2Recruiting34 enrolled2026

    Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion

    Alaa Sada

    Mild Autonomous Cortisol Secretion (MACS) · Adrenalectomy; Status

  • NCT07588438Phase 4Recruiting160 enrolled2026

    Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay.

    Las Rías Medical Center

    Obesity · Diabetes Mellitus, Type 2

  • NCT07697391Phase 4Not Yet Recruiting285 enrolled2026

    AI-Assisted Lifestyle Intervention Versus Tirzepatide for Obesity and Newly Diagnosed Type 2 Diabetes

    The First Affiliated Hospital of Anhui Medical University

    Obesity · Diabetes Mellitus, Type 2

  • NCT07738276Phase 3Not Yet Recruiting60 enrolled2026

    Evaluation of the Efficacy and Safety of Tirzepatide, a Dual GLP-1/GIP Agonist, on Functional Capacity in Reduced Ejection Fraction Heart Failure Patients With Obesity

    Shahid Beheshti University of Medical Sciences

    Heart Failure and Reduced Ejection Fraction · Obesity & Overweight · Tirzepatide

  • NCT06820281Phase 2Recruiting44 enrolled2026

    Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes

    Victor Chang Cardiac Research Institute

    Type 1 Diabetes Mellitus

  • NCT07265752Phase 2Not Yet Recruiting6 enrolled2026

    Tirzepatide for the Treatment of Cannabis Use Disorder

    Brigham and Women's Hospital

    Cannabis Use Disorder

  • NCT07706088Phase 4Not Yet Recruiting40 enrolled2026

    Effect of Tirzepatide on Diabetic Peripheral Sensorimotor Neuropathy

    Post Graduate Institute of Medical Education and Research, Chandigarh

    Neuropathy, Small Fiber · Diabete Mellitus

  • NCT07635953Phase 3Not Yet Recruiting296 enrolled2026

    New Triple Combination Therapy in Newly Diagnosed Type 2 Diabetes

    Sun Yat-sen University

    Diabetes Mellitus

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT07622992Not Yet Recruiting96 enrolled2026

    Preoperative Optimization With Tirzepatide, Ketogenic Diet, or Standard Care Before One Anastomosis Gastric Bypass Surgery

    Mario Musella MD

    Obesity (BMI > 35) and Diabetes Mellitus · Obesity (BMI > 35) and Dyslipemia · Obesity (BMI > 35) and High Blood Pressure

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT07707778Phase 4Enrolling By Invitation60 enrolled2026

    Tirzepatide's Effects on Epigenetic Aging and Metabolic Restoration in Virally Suppressed People With HIV

    National Taiwan University Clinical Trial Center

    Human Immunodeficiency Virus (HIV) · Metabolic Dysfunction Associated Steatotic Liver Disease · Dyslipidaemia · Diabetes Mellitus

  • NCT07382024Not Yet Recruiting200 enrolled2026

    Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation

    National Taiwan University Hospital

    Atrial Fibrillation Ablation · Persistent Atrial Fibrillation · Obesity & Overweight

  • NCT07046819Phase 2Recruiting120 enrolled2026

    Tirzepatide in MetALD

    National Institute on Alcohol Abuse and Alcoholism (NIAAA)

    Metabolic Alcohol-associated Liver Disease · Alcohol Use Disorder

  • NCT07257484Phase 4Recruiting30 enrolled2026

    Tirzepatide's Role in Postmenopausal HR+ Breast Cancer Survivors

    Weill Medical College of Cornell University

    Obesity (Disorder) · Breast Cancer

  • NCT07602699Phase 2Recruiting300 enrolled2026

    Multi-Site Trial of Tirzepatide for Smoking Cessation

    University of Southern California

    Smoking Cessation · Smoking Behaviors

  • NCT07387796Recruiting40 enrolled2026

    Clinical and Neurobehavioral Changes With Weight Loss Drug Discontinuation and Reinitiation

    The University of Texas at Dallas

    Drug Discontinuation · Substance Use Disorders · Eating Behavior Changes · Tirzepatide

  • NCT07605247Phase 2Not Yet Recruiting30 enrolled2026

    Tirzepatide in the Treatment of Endometrial Cancer

    Rutgers, The State University of New Jersey

    Endometrial Cancer

  • NCT07650149Recruiting200 enrolled2026

    Genetic, Microbiological and Behavioral Factors in Obesity

    Jan Kochanowski University

    Obesity & Overweight · Obesity · Genetics

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT07527910Phase 2Recruiting204 enrolled2026

    A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD

    Regeneron Pharmaceuticals

    Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

  • NCT07559500Phase 1Recruiting176 enrolled2026

    Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)

    National Institute on Alcohol Abuse and Alcoholism (NIAAA)

    Alcohol Use Disorder (AUD)

  • NCT07284511Phase 2/3Recruiting105 enrolled2026

    A Clinical Trial Using Tirzepatide to Help Adults With Type 1 Diabetes Automatically Control Their Blood Sugar

    McGill University Health Centre/Research Institute of the McGill University Health Centre

    Type 1 Diabetes · Type 1 Diabetes Mellitus · T1D · T1DM

  • NCT07574723Recruiting68 enrolled2026

    Tirzepatide Titration to Reduce Side Effects in Individuals With Obesity

    Dasman Diabetes Institute

    Obesity

  • NCT07567378Not Yet Recruiting30 enrolled2026

    CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry

    JULIO GRANADOS MONTIEL

    Psoriatic Arthritis · Osteoarthitis · Knee · Diabetes (DM)

  • NCT07179120Phase 2Not Yet Recruiting180 enrolled2026

    Can Fat-Burning Shots Boost Fertility? Comparing Weight-Loss Injections vs. Healthy Habits for Obese Men With Low Sperm Health

    First Affiliated Hospital of Wenzhou Medical University

    Obesity-related Male Infertility

  • NCT07633639Recruiting200 enrolled2026

    GLP-1 Therapy After Bariatric Surgery in Chinese Patients With Obesity

    China-Japan Friendship Hospital

    Obesity

  • NCT07588984Not Yet Recruiting2,310 enrolled2026

    GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study

    Noom Inc.

    Obesity & Overweight · Weight Loss · Preventative Health · Body Weight

  • NCT07555730Phase 4Not Yet Recruiting400 enrolled2026

    AI-assisted Multi-domain Lifestyle Versus Tirzepatide for Weight Loss Maintenance in Adults With Type 2 Diabetes (AIM-MAINTAIN)

    Huazhong University of Science and Technology

    Overweight or Obesity; Type 2 Diabetes · Weight Loss Maintenance

  • NCT07065552Early Phase 1Recruiting20 enrolled2026

    Tirzepatide in Obesity-Driven Endometrial Cancer

    UNC Lineberger Comprehensive Cancer Center

    Endometrial Cancer · Obesity

  • NCT07228741Phase 2Recruiting20 enrolled2026

    Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity

    St. Jude Children's Research Hospital

    Acute Lymphoblastic Leukemia · Obesity

  • NCT07218445Phase 4Recruiting40 enrolled2026

    The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity

    Mayo Clinic

    Obesity · Menopause Hot Flashes

  • NCT06811324Phase 2Recruiting20 enrolled2026

    Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults

    The University of Texas Health Science Center at San Antonio

    Obesity Prevention · Sarcopenia in Elderly · Cardiovascular Function · GLP - 1

  • NCT07504172Not Yet Recruiting1,700 enrolled2026

    Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity

    Radboud University Medical Center

    Overweight , Obesity · Obesity (Disorder)

  • NCT07521631Phase 2Recruiting372 enrolled2026

    Efficacy and Safety of HDM1005 Compared to Tirzepatide in Obese Adults Without Diabetes

    Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.

    Obesity

  • NCT07589322Recruiting120 enrolled2026

    Comparative Observation of Metabolic and Pharmacologic Adipose Remodeling With Enhanced Incretin AgonisTs

    Tri-Service General Hospital (TSGH)

    Obesity and Metabolic Syndrome

  • 2025-522674-36-00Ongoing505 enrolled2026

    N1T-MC-MALO

    Eli Lilly & Co.

    Metabolic Dysfunction-Associated Steatotic Liver Disease

  • NCT07443956Recruiting45 enrolled2026

    Combination of Biologic and Anti-obesity Therapies in Psoriatic Arthritis

    NHS Greater Glasgow and Clyde

    Psoriatic Arthritis (PsA) · Obesity & Overweight

  • NCT07463846Phase 1/2Recruiting156 enrolled2026

    A Study to Evaluate ALN-2232 in Participants With Obesity

    Alnylam Pharmaceuticals

    Obesity

  • NCT07483801Phase 4Not Yet Recruiting112 enrolled2026

    DECODE - Haemodynamic Effects Of Semaglutide and Tirzepatide - a Series of Pilot Studies

    Cambridge University Hospitals NHS Foundation Trust

    Cardiovascular Diseases

  • NCT07492563Not Yet Recruiting300 enrolled2026

    Safety and Effectiveness of Tirzepatide in Patients With Obesity at Hospital de Clínicas, Paraguay

    LABORATORIOS INDUFAR

    Obesity · Type 2 Diabetes Mellitus · Overweight With Comorbidities

  • NCT07438444Phase 4Active Not Recruiting344 enrolled2026

    A Study of Tirzepatide (LY3298176) in Adult Participants in India With Either Type 2 Diabetes Mellitus or Obesity

    Eli Lilly and Company

    Diabetes Mellitus, Type 2 · Obesity · Overweight

  • NCT07220473Phase 2Recruiting90 enrolled2026

    Tirzepatide to Slow Biological Aging

    The University of Texas Medical Branch, Galveston

    Aging · LONGEVITY 1

  • NCT07095517Phase 1Recruiting20 enrolled2026

    Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors

    Massachusetts General Hospital

    Colorectal Cancer Prevention · Colorectal Adenoma

  • NCT07619508Completed100,000 enrolled2026

    Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.

    Brigham and Women's Hospital

    Obesity · Overweight

  • ISRCTN8357603724 enrolled2026

    A phase 2, safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy study of a subcutaneous injection of BC-006 and tirzepatide in adults with obesity

    BaseCure Therapeutics Inc.

    Obesity

  • NCT07481747Phase 3Recruiting2,539 enrolled2026

    Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo in Participants Who Are Either Obese or Overweight With Weight-Related Comorbidities (SURMOUNT-1)

    Hudson Biotech

    Obesity · Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities

  • NCT07176663Not Yet Recruiting15 enrolled2026

    Efficacy and Safety of Tirzepatide (Spartina) in Chronic Kidney Failure

    Shahid Beheshti University of Medical Sciences

    Obesity

  • NCT06651177Phase 2Recruiting310 enrolled2026

    Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

    T. John Winhusen, PhD

    Opioid Use Disorder · Opioid Use Disorder, Moderate · Opioid Use Disorder, Severe

  • NCT07417618Completed60,000 enrolled2026

    INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)

    Brigham and Women's Hospital

    Type 2 Diabetes · Overweight · ASCVD

  • NCT07398222Recruiting30 enrolled2026

    Gastric Content in Fasting Volunteers and in Tirzepatide Users: an Observational and Cross-sectional Study

    Hospital Israelita Albert Einstein

    Full Stomach Status

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT07354880Phase 4Not Yet Recruiting30 enrolled2026

    Effect of Tirzepatide on Cardiovascular and Metabolic Parameters in Obese Adult Patients With Congenital Heart Disease

    University Medical Centre Ljubljana

    Obesity & Overweight · Adult Congenital Heart Disease

  • ISRCTN2244642486 enrolled2026

    IIH-Advance: A randomised clinical trial to determine the effects of weight loss, induced by a weight loss drug (Tirzepatide), in adults with active idiopathic intracranial hypertension

    University of Birmingham

    Idiopathic intracranial hypertension

  • NCT07292519Phase 2Not Yet Recruiting46 enrolled2026

    Tirzepatide Combined With Cognitive-Behavioural Therapy (CBT) for Adults With Alcohol Use Disorder (AUD) and Overweight/Obesity (OOB)

    South West Sydney Local Health District

    Alcohol Use Disorder (AUD) · Overweight or Obese · Comorbidities and Coexisting Conditions

  • NCT07299084Phase 1Active Not Recruiting40 enrolled2026

    A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus

    Eli Lilly and Company

    Diabetes Mellitus, Type 2 · Overweight · Obesity

  • NCT07423247Phase 4Recruiting30 enrolled2026

    Tirzepatide (Spartina) in Obese Kidney Transplant Recipients

    Shahid Beheshti University of Medical Sciences

    Tirzepatide

  • NCT07364175Recruiting60 enrolled2026

    A Trial Within Cohort Feasibility Study Design Comparing Standard of Care Versus Weight Loss (Achieved Through Tirzepatide) for Obesity-related Hypertension in Young Adults

    Cambridge University Hospitals NHS Foundation Trust

    Hypertension · Obesity & Overweight

  • NCT07640139Enrolling By Invitation125,000 enrolled2026

    Estimating the Impact of Obesity Medications on Clinical and Economic Outcomes

    Indiana University

    Obesity

  • NCT07373834Recruiting30 enrolled2026

    Tirzepatide and Muscle Outcomes in Obesity

    University Medical Centre Ljubljana

    Obesity (Disorder)

  • NCT07319975Not Yet Recruiting48 enrolled2025

    Effect of Semaglutide and Tirzepatide Combined With Exercise in Obesity

    Istanbul Galata University

    Obesity

  • NCT07326111Phase 4Recruiting198 enrolled2025

    A Clincial Study Testing Tirzepatide on Reproductive Function and Metabolic Health in Women With PCOS Who Are Overweight or Obese

    University of Bonn

    Polycystic Ovary Syndrome (PCOS) · Obesity & Overweight

  • 2024-515982-32-00Ongoing198 enrolled2025

    MED1-202202

    Rheinische Friedrich-Wilhelms-Universitaet Bonn

    Overweight or Obesity, Polycystic Ovary Syndrome (PCOS)

  • NCT07247084Phase 4Recruiting3,000 enrolled2025

    A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)

    Eli Lilly and Company

    Obesity

  • NCT06935838Phase 2Completed12 enrolled2025

    Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV

    University of Hawaii

    Obesity and Overweight · HIV · Chronic Inflammation

  • NCT05933499Phase 2Recruiting63 enrolled2025

    Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity

    Massachusetts General Hospital

    Obesity

  • NCT07202247Phase 2Recruiting60 enrolled2025

    Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy Diet) to Improve Cardiometabolic Health in Prostate Cancer Patients During Androgen Deprivation Therapy, IMPACT-ADT Trial

    City of Hope Medical Center

    Prostate Carcinoma · Recurrent Prostate Carcinoma

  • NCT07245771Phase 1/2Recruiting104 enrolled2025

    Phase 1/2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effect on Body Weight of RN3161 as Monotherapy and in Combination With Tirzepatide in Adults With Overweight and Obesity

    Ikaria Bioscience Pty Ltd

    Obesity &Amp; Overweight

  • NCT07128082Phase 2Active Not Recruiting1,000 enrolled2025

    The Long COVID Treatment Trial

    Scripps Translational Science Institute

    Long COVID

  • NCT07165028Phase 3Recruiting4,500 enrolled2025

    A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

    Eli Lilly and Company

    Metabolic Dysfunction-Associated Steatotic Liver Disease

  • NCT07154719Phase 4Active Not Recruiting50 enrolled2025

    GLP-1R Actions on Muscle and the Skeleton

    Pennington Biomedical Research Center

    Musculoskeletal Abnormalities · Obesity · Sarcopenic Obesity · Osteoporosis

  • NCT06994338Phase 2Recruiting42 enrolled2025

    Tirzepatide for Alcohol Use Disorder

    University of Southern California

    Alcohol Use Disorder · Obesity and Overweight · Alcohol

  • NCT06801015Phase 4Active Not Recruiting30 enrolled2025

    Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor Functions

    Mayo Clinic

    Obesity

  • NCT07203677Completed49,065 enrolled2025

    Comparative Effectiveness of Tirzepatide Versus Sitagliptin in Individuals at Cardiovascular Risk (TIRZSITA-CVOT)

    Brigham and Women's Hospital

    Type2 Diabetes Mellitus · Atherosclerotic Cardiovascular Disease

  • 2024-520210-21-00Ongoing171 enrolled2025

    I6T-MC-AMCE

    Eli Lilly & Co.

    Crohn’s Disease, Obesity or Overweight

  • NCT06847399Phase 2Recruiting105 enrolled2025

    Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating Disorder

    Johns Hopkins University

    Obesity and Overweight · Binge Eating Disorder

  • NCT06727331Phase 2Recruiting20 enrolled2025

    Study of Tirzepatide for Recovery and Alcohol Use Management

    Brigham and Women's Hospital

    Alcohol Use Disorder (AUD)

  • NCT07091734Phase 2Recruiting32 enrolled2025

    Tirzepatide for Partial Lipodystrophy Treatment: A New Horizon in 2024

    University of Michigan

    Lipodystrophy, Partial

  • NCT07099742Not Yet Recruiting364 enrolled2025

    Effectiveness and Safety of Tirzepatide Among Participants With Obesity With or Without Type 2 Diabetes Mellitus (T2DM)

    Dr. Md. Alimur Reza

    Obesity

  • NCT07115069Active Not Recruiting60 enrolled2025

    Comparison of Body Composition Changes With Weight Loss Interventions

    Vanderbilt University Medical Center

    Obesity

  • NCT06073184Phase 2Not Yet Recruiting71 enrolled2025

    Weight-loss Drug for Fertility-Sparing Treatment of Atypical Hyperplasia and Low-grade Cancer of the Endometrium

    University Health Network, Toronto

    Endometrial Cancer · Atypical Hyperplasia

  • NCT07096908Phase 4Recruiting60 enrolled2025

    Tirzepatide Use in People With Obesity and Type 1 Diabetes

    Dasman Diabetes Institute

    Type1diabetes · Obesity

  • NCT06861439Phase 4Active Not Recruiting40 enrolled2025

    GLP-1s to Enhance Lasting Optimal Weight

    Wake Forest University Health Sciences

    Obesity

  • 2024-519561-22-00Temporarily Halted78 enrolled2025

    BC45538

    F. Hoffmann-La Roche AG

    Obesity

  • ISRCTN1817637560 enrolled2025

    A phase 1, safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of a subcutaneous injection of BC-006 in adults with obesity-part 2

    BaseCure Therapeutics Inc.

    Diet and Nutrition

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT06759701Early Phase 1Recruiting30 enrolled2025

    Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility Study

    M.D. Anderson Cancer Center

    Diabetes · Prostate Cancer

  • NCT06934642Early Phase 1Recruiting8 enrolled2025

    Effect of Tirzepatide on Markers of MASLD in Patients With Obesity

    University of New Mexico

    MASLD · Obesity

  • NCT06937099Phase 3Recruiting290 enrolled2025

    Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

    Eli Lilly and Company

    Crohn's Disease · Obesity or Overweight

  • NCT06937086Phase 3Recruiting350 enrolled2025

    Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

    Eli Lilly and Company

    Ulcerative Colitis · Obesity or Overweight

  • NCT07000955Phase 1/2Active Not Recruiting98 enrolled2025

    Tolerance and Pharmacokinetic/Pharmacokinetic Study of IBI362 15mg in Patients With Moderate to Severe Obesity

    Innovent Biologics (Suzhou) Co. Ltd.

    Obesity

  • NCT07293325Recruiting66 enrolled2025

    Semaglutide and Tirzepatide for Genetic Aging Delay in Adults With Obesity

    Second Affiliated Hospital, Zhejiang University, School of Medicine

    Adults With Simple Obesity

  • NCT06901349Phase 2Withdrawn2025

    A Study of Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Participants With Obesity or Overweight With Type 2 Diabetes

    Eli Lilly and Company

    Obesity · Overweight

  • NCT07094568Recruiting72 enrolled2025

    Tirzepatide vs Liraglutide in Bone

    National and Kapodistrian University of Athens

    Obesity (Disorder)

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT06976853Phase 2Recruiting60 enrolled2025

    Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

    Washington University School of Medicine

    Crohn Disease (CD)

  • NCT06962280Phase 3Active Not Recruiting465 enrolled2025

    A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight

    Eli Lilly and Company

    Type 1 Diabetes · Obesity · Overweight

  • NCT06937203Phase 1/2Recruiting150 enrolled2025

    A First-In-Human Study of ARO-ALK7 in Adults With Obesity With and Without Type 2 Diabetes Mellitus

    Arrowhead Pharmaceuticals

    Obesity · Diabetes Mellitus, Type 2

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT06965413Phase 2Active Not Recruiting285 enrolled2025

    A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity

    Hoffmann-La Roche

    Obesity · Overweight · Overweight With One Weight Related Comorbidity

  • NCT06939088Phase 2Recruiting108 enrolled2025

    Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder

    Anders Fink-Jensen, MD, DMSci

    Alcohol Use Disorder · Alcohol Abuse/Dependence · Alcohol Dependence · Alcoholism

  • NCT06901245Phase 4Recruiting36 enrolled2025

    Tirzepatide in PWS, HO and GNSO

    Grace Kim

    Prader-Willi Syndrome · Hypothalamic Obesity · Obesity/Therapy

  • 2024-518608-28-00Ongoing108 enrolled2025

    Effect of tirzepatide on alcohol intake and reward processing in patients diagnosed with schizophrenia and alcohol use disorder

    Psykiatrisk Center Kobenhavn

    Schizophrenia and Alcohol Use Disorder

  • NCT07057310Phase 4Enrolling By Invitation30 enrolled2025

    Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal Women

    Mayo Clinic

    Obesity · Menopause

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT06914895Phase 3Active Not Recruiting905 enrolled2025

    A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight

    Eli Lilly and Company

    Type 1 Diabetes · Obesity · Overweight

  • NCT06916065Phase 1Completed188 enrolled2025

    A Study of Eloralintide (LY3841136) and Eloralintide With Tirzepatide in Participants With Overweight or Obesity

    Eli Lilly and Company

    Overweight · Obesity

  • NCT06802081Phase 2Recruiting100 enrolled2025

    TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation

    The Cleveland Clinic

    Atrial Fibrillation · Obesity

  • NCT06911203Phase 2Recruiting90 enrolled2025

    A Study of BGM0504 in Participants With Obesity

    BrightGene Bio-Medical Technology Co., Ltd.

    Obesity

  • ISRCTN17524311108 enrolled2025

    Prevent from home: young person and buddies’ cardiovascular health improvement feasibility study

    King's College London

    Hypertension in pregnancy, gestational diabetes

  • NCT06721507Phase 4Recruiting50 enrolled2025

    2024 Tirzepatide-Bariatric Surgery

    Marlene Starr

    Obesity and Obesity-related Medical Conditions · Bariatric Surgery

  • NCT06890611Phase 1Completed125 enrolled2025

    A Study of Bimagrumab Alone (LY3985863) and Bimagrumab With Tirzepatide (LY900042) in Healthy Participants

    Eli Lilly and Company

    Healthy

  • NCT06857942Phase 4Recruiting200 enrolled2025

    A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

    Eli Lilly and Company

    Psoriasis · Overweight or Obesity

  • NCT06893211Phase 2Completed34 enrolled2025

    Effect of Tirzepatide on Brown Adipose Tissue in Obesity

    University Medical Centre Ljubljana

    Obesity

  • NCT06734273Early Phase 1Recruiting42 enrolled2025

    Randomized Control Trial of Sleeve Gastrectomy With Tirzepatide in Maximizing Weight Loss

    Nicholas Skertich

    Obesity and Obesity-related Medical Conditions

  • NCT06582875Phase 2Recruiting126 enrolled2025

    Glucagon-Like Peptide-1 Receptor Agonist in ADPKD

    University of Colorado, Denver

    Autosomal Dominant Polycystic Kidney · Obesity

  • NCT06864026Phase 4Recruiting200 enrolled2025

    A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

    Eli Lilly and Company

    Psoriatic Arthritis · Overweight or Obesity

  • NCT06774079Phase 4Recruiting24 enrolled2025

    Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) Patients

    University of Miami

    Crohn Disease

  • NCT06737042Phase 2Completed326 enrolled2025

    Efficacy and Safety of GZR18 Every 2 Weeks Versus Tirzepatide and Placebo in Obese or Overweight Participants

    Gan and Lee Pharmaceuticals, USA

    Obesity and Overweight

  • NCT06630585Phase 3Recruiting42 enrolled2025

    GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes

    University of Bern

    Type 1 Diabetes (T1D)

  • NCT06745128Phase 2Active Not Recruiting45 enrolled2025

    Tirzepatide for Obesity and Meth Use Disorder

    University of Texas Southwestern Medical Center

    Obesity · Methamphetamine Use Disorder

  • NCT07382180Completed254 enrolled2025

    Real-World Tirzepatide Therapy in Post-Bariatric Weight Regain and Preoperative Obesity Patients

    Azienda Sanitaria Locale Napoli 2 Nord

    Obesity & Overweight · Weight Regain · Obesity, Morbid

  • NCT06431308Recruiting120 enrolled2025

    Nutritional Therapy to Incretin-based Anti-obesity Medications in the Management of Gastrointestinal Adverse Events

    Ariel University

    Obesity; Drug

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT06803888Phase 4Active Not Recruiting125 enrolled2025

    Bariatric Surgery vs. Semaglutide vs. Tirzepatide

    Ali Aminian

    Obesity and Obesity-related Medical Conditions

  • ISRCTN10203365324 enrolled2025

    Investigating and optimising physical function with weight loss

    University of Leicester

    Overweight or obesity

  • NCT06914154Completed11,265 enrolled2025

    Emulation of the SUMMIT Heart Failure Trial in Healthcare Claims Data

    Brigham and Women's Hospital

    Diabetes Mellitus, Type 2 · Heart Failure With Preserved Ejection Fraction (HFPEF)

  • NCT06914141Completed28,118 enrolled2025

    Comparative Effectiveness of Tirzepatide Versus Semaglutide in Individuals With Heart Failure With Preserved Ejection Fraction

    Brigham and Women's Hospital

    Diabetes Mellitus, Type 2 · HFpEF - Heart Failure With Preserved Ejection Fraction

  • NCT06657209Phase 4Recruiting104 enrolled2025

    Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide

    Stanford University

    Diabetes Mellitus, Type 2 · Diabetes · Type 2 Diabetes · Pre Diabetes

  • NCT06918405Phase 3Active Not Recruiting440 enrolled2025

    Efficacy and Safety of Tirzepatide for Weight Management

    Chittagong Medical College

    Obesity and Obesity-related Medical Conditions

  • NCT06980623Active Not Recruiting26,000 enrolled2025

    Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction

    Brigham and Women's Hospital

    Type 2 Diabetes · Heart Failure

  • NCT07638592Completed91 enrolled2025

    Tirzepatide-Based Prehabilitation Before Elective Ventral and Incisional Hernia Repair in Patients With Obesity

    Azienda Sanitaria Locale Napoli 2 Nord

    Obese Adults · Hernia Abdominal Wall · Prehabilitation

  • NCT06751589Early Phase 1Recruiting36 enrolled2024

    A Study of a Weight Loss Intervention in People With Endometrial Cancer

    Memorial Sloan Kettering Cancer Center

    Endometrial Cancer

  • NCT07303556Active Not Recruiting120 enrolled2024

    Improving Cardiovascular Disease Diagnosis and Treatment in Kazakhstan Using Metabolic Correction With GLP-1 Drugs

    Nazarbayev University

    Heart Failure · Diabete Type 2 · Arterial Hypertension

  • NCT06700538Phase 1/2Recruiting180 enrolled2024

    A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes Mellitus

    Arrowhead Pharmaceuticals

    Obesity

  • NCT06648031Phase 1Completed148 enrolled2024

    Comparison of the Safety, Efficacy and Pharmacokinetics of DehydraTECH -CBD and DehydraTECH-GLP1 Agonists Alone or in Combination, in Overweight or Obese, Pre- and Type 2 Diabetic Participants

    Lexaria Bioscience Corp.

    Type2diabetes

  • NCT06517212Phase 2Recruiting48 enrolled2024

    Tirzepatide Weight Loss for MRD+ Early Breast Cancer

    Baylor Research Institute

    Breast Cancer · Breast Neoplasms · Breast Cancers

  • NCT06191848Phase 4Recruiting352 enrolled2024

    Subcutaneous Tirzepatide Once-weekly in Patients With Obesity and Knee Osteoarthritis (STOP KNEE-OA)

    University of Melbourne

    Obesity · Knee Osteoarthritis · Osteoarthritis, Knee

  • NCT06246799Phase 3Recruiting256 enrolled2024

    Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

    The University of Texas Health Science Center at San Antonio

    Type 2 Diabetes (Adult Onset)

  • NCT06534411Phase 3Completed1,023 enrolled2024

    A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both

    Novo Nordisk A/S

    Diabetes Mellitus, Type 2

  • NCT06779929Completed70,000 enrolled2024

    Comparative Study of Tirzepatide Versus Dulaglutide (SURPASS CVOT) or Semaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

    Brigham and Women's Hospital

    Type 2 Diabetes

  • NCT06662383Phase 3Active Not Recruiting800 enrolled2024

    A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity

    Eli Lilly and Company

    Obesity

  • NCT06467604Active Not Recruiting7 enrolled2024

    CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users

    University of California, Davis

    Obesity

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT06162715Phase 2/3Active Not Recruiting30 enrolled2024

    GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial

    Vanderbilt University Medical Center

    Severe Obesity · Obesity · BMI Greater Than 30

  • NCT06518837Phase 2Recruiting40 enrolled2024

    Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer

    Rutgers, The State University of New Jersey

    Hormone Receptor-Positive Breast Cancer · HER2-Negative Breast Cancer

  • 2024-511450-49-00Temporarily Halted225 enrolled2024

    J1I-MC-GZBP

    Eli Lilly & Co.

    Obesity

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT06643728Phase 2Active Not Recruiting252 enrolled2024

    A Study to Investigate Weight Management With Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Adults With Obesity or Overweight

    Eli Lilly and Company

    Obesity · Overweight

  • NCT06635057Phase 4Completed166 enrolled2024

    A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan

    Eli Lilly and Company

    Type 2 Diabetes

  • NCT07088718Completed44,671 enrolled2024

    Prediction of the SURPASS-CVOT Cardiovascular Outcome Trial in Healthcare Claims Data

    Brigham and Women's Hospital

    Type 2 Diabetes · Major Adverse Cardiac Events · Cardiovascular (CV) Risk

  • NCT07096063Completed887,132 enrolled2024

    Comparative Effectiveness of Tirzepatide and Semaglutide in Individuals at Cardiovascular Risk

    Brigham and Women's Hospital

    Type 2 Diabetes · Overweight · Cardiovascular (CV) Risk

  • NCT06606821Phase 4Recruiting124 enrolled2024

    The Effects of Tirzepatide in People With Overweight/Obesity and Coronary Artery Disease

    Tina Vilsbøll

    Coronary Artery Disease · Coronary Microvascular Dysfunction · Overweight or Obesity · Stable Angina Pectoris

  • NCT06588283Phase 3Completed281 enrolled2024

    Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight

    Eli Lilly and Company

    Psoriasis · Obesity

  • 2023-507655-30-00Temporarily Halted43 enrolled2024

    I8F-MC-GPIX

    Eli Lilly & Co.

    Obesity

  • NCT06588296Phase 3Completed279 enrolled2024

    Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight

    Eli Lilly and Company

    Psoriatic Arthritis · Obesity

  • NCT06603571Phase 2Active Not Recruiting367 enrolled2024

    A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes

    Eli Lilly and Company

    Obesity · Overweight

  • NCT06485089Completed25 enrolled2024

    Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers

    University of Kansas Medical Center

    Obesity · Breast Cancer Risk

  • 2023-505270-15-00Ongoing124 enrolled2024

    The effects of tirzepatIDE on coronAry pLaque lipid content and myocardial microvascular function in people with overweight or obesity and CORonary disease

    Steno Diabetes Center Copenhagen

    Overweight and obesity

  • NCT06565611Phase 2Active Not Recruiting108 enrolled2024

    A Phase 2 Study Evaluating the Co-Administration of Bremelanotide With Tirzepatide for the Treatment of Obesity

    Palatin Technologies, Inc

    Obesity

  • ISRCTN148120041,000 enrolled2024

    The effectiveness and sustainability of health outcomes from an advanced digital weight-loss programme in the UK

    Eucalyptus

    Overweight and obesity

  • NCT06533527Phase 4Completed69 enrolled2024

    Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy

    The Cleveland Clinic

    Diabetes Mellitus, Type 2 · Obesity · Gastroparesis

  • NCT06515418Phase 2Terminated204 enrolled2024

    Efficacy and Safety of Oral Azelaprag Plus Once Weekly Tirzepatide Compared with Tirzepatide Alone in Participants with Obesity Aged 55 Years and Over

    BioAge Labs, Inc.

    Obesity

  • NCT06439277Phase 3Recruiting300 enrolled2024

    A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

    Eli Lilly and Company

    Obesity · Weight Gain

  • NCT06445075Phase 2Completed102 enrolled2024

    Efficacy and Safety of Apitegromab for the Treatment of Adults Who Are Overweight or Obese

    Scholar Rock, Inc.

    Overweight and Obesity

  • 2024-514909-64-00Revoked10 enrolled2024

    Towards a personalized precision medicine in rare disease: tirzepatide (a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist) monotherapy in patients with Wolfram syndrome type 1.

    Ospedale San Raffaele S.r.l.

    Wolfram syndrome type 1

  • NCT07368855Completed90 enrolled2024

    GLP-1 Medicines and Mental Health Changes

    University of California, San Diego

    Obesity · Depression · GLP-1

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT06373146Phase 2Completed392 enrolled2024

    A Study of Tirzepatide (LY3298176) Plus Mibavademab Compared With Tirzepatide Alone in Adult Participants With Obesity

    Eli Lilly and Company

    Obesity

  • NCT06297616Phase 1Completed128 enrolled2024

    A Study of LY3841136 in Japanese Participants With Obesity or Overweight

    Eli Lilly and Company

    Obesity · Overweight

  • NCT06345066Phase 1Completed96 enrolled2024

    A Study of LY3841136 in Overweight and Obese Participants

    Eli Lilly and Company

    Obesity · Overweight

  • NCT06326060Phase 2Completed354 enrolled2024

    A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Help People With Excess Body Weight Lose Weight

    Novo Nordisk A/S

    Obesity

  • NCT06326047Phase 2Completed299 enrolled2024

    A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Lower Blood Sugar in People With Type 2 Diabetes

    Novo Nordisk A/S

    Diabetes Mellitus, Type 2

  • NCT06301256Unknown20 enrolled2024

    Evaluate the Efficacy of TIRZEPATIDE for the Treatment of Moderate to Severe HS Hidradenitis Suppurativa

    Florida Academic Centers Research and Education, LLC

    Hidradenitis Suppurativa

  • NCT06221969Phase 3Completed1,024 enrolled2024

    A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor

    Novo Nordisk A/S

    Type 2 Diabetes

  • NCT05708859Phase 4Recruiting120 enrolled2024

    Effect of Tirzepatide on Progression of Coronary Atherosclerosis Using MDCT

    Matthew J. Budoff

    Type II Diabetes · Atherosclerosis

  • NCT05659368Phase 2Unknown10 enrolled2024

    Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1

    Ospedale San Raffaele

    Wolfram Syndrome

  • NCT07701005Completed154 enrolled2024

    Non-Invasive Hepatic and Metabolic Index Changes After Incretin Therapy in Overweight/Obesity

    Goztepe Prof Dr Suleyman Yalcın City Hospital

    Steatosis of Liver · Metabolic Liver Injury · Obesity · Overweight

  • NCT06131437Phase 3Completed809 enrolled2023

    A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight

    Novo Nordisk A/S

    Obesity

  • NCT06143956Phase 2Recruiting1,481 enrolled2023

    A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

    Eli Lilly and Company

    Obesity · Overweight

  • NCT05912621Phase 2Recruiting66 enrolled2023

    Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity

    Stanford University

    Obesity · Overweight and Obesity · Overweight

  • NCT06075667Phase 3Active Not Recruiting160 enrolled2023

    A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

    Eli Lilly and Company

    Obesity · Overweight

  • NCT05751720Phase 1/2Unknown30 enrolled2023

    Effect on Non-Alcoholic Fatty Liver Disease in Patients With Type 2 Diabetes Mellitus With Gastric Inhibitory Polypeptide/Glucagon Like Peptide-1 Analogue

    Dr Adnan Agha

    Non-Alcoholic Fatty Liver Disease · Non-alcoholic Steatohepatitis · Type 2 Diabetes · Liver Fat

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • NCT06037252Phase 2Active Not Recruiting414 enrolled2023

    A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and Obesity

    Eli Lilly and Company

    Type 2 Diabetes · Obesity

  • NCT06047548Phase 3Completed441 enrolled2023

    A Study of LY3298176 (Tirzepatide) For the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

    Eli Lilly and Company

    Overweight · Obesity

  • NCT07309094Recruiting250 enrolled2023

    Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKD

    Cardenal Herrera University

    Chronic Kidney Disease stage3 · Chronic Kidney Disease stage4 · Chronic Kidney Disease Stage 1 · Chronic Kidney Disease Stage 2

  • NCT06009653Phase 4Withdrawn2023

    Effects of Tirzepatide Plus Intensive Lifestyle Therapy on Body Weight and Metabolic Health in Latinos With Obesity

    Washington University School of Medicine

    Obesity · Metabolic Disease

  • NCT05963022Phase 3Completed206 enrolled2023

    A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes (SURPASS-CN-MONO)

    Eli Lilly and Company

    Type 2 Diabetes

  • NCT05978713Phase 1Completed11 enrolled2023

    A Study of Tirzepatide (LY3298176) in Healthy Lactating Females

    Eli Lilly and Company

    Healthy

  • NCT06354101Withdrawn2023

    The Purpose of This Registry Study is to Learn More About Metabolic Health: Approximately 15,000 Participants Who Are Overweight or Have Obesity With or Without Metabolic Diseases Are Expected to Participate in This Registry Study.

    CorEvitas

    Metabolic Health

  • NCT05756764Active Not Recruiting30 enrolled2023

    Anti-obesity Pharmacotherapy and Inflammation

    Louisiana State University Health Sciences Center in New Orleans

    Obesity

  • NCT05822544Phase 1Active Not Recruiting564 enrolled2023

    Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or Without Diabetes

    OrsoBio, Inc

    Healthy Subjects · Obesity · Type 2 Diabetes

  • NCT05822830Phase 3Completed751 enrolled2023

    A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related Comorbidities

    Eli Lilly and Company

    Obesity · Overweight

  • NCT05810597Phase 1Completed65 enrolled2023

    A Research Study Looking at Similarity Between Tirzepatide Versions for Different Injection Devices

    Eli Lilly and Company

    Healthy

  • NCT05706506Phase 4Completed152 enrolled2023

    A Study of Tirzepatide (LY3298176) in Adults With Type 2 Diabetes Switching From a GLP-1 RA (SURPASS-SWITCH-2)

    Eli Lilly and Company

    Type 2 Diabetes · Diabetes Mellitus, Type 2

  • 2023-506082-60-00Revoked44 enrolled2023

    I8F-MC-GPIG

    Eli Lilly & Co.

    Obesity, Overweight, CKD, Chronic Kidney Disease, T2D, Type 2 Diabetes

  • NCT05536804Phase 2Active Not Recruiting140 enrolled2023

    A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

    Eli Lilly and Company

    Overweight · Obesity · Chronic Kidney Disease · Type 2 Diabetes

  • NCT05696847Phase 1Completed28 enrolled2023

    A Study of Tirzepatide (LY3298176) in Pediatric Participants With Obesity

    Eli Lilly and Company

    Obesity

  • NCT05691712Phase 3Completed257 enrolled2023

    A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes

    Eli Lilly and Company

    Diabetes Type 2 · Diabetes Mellitus · Glucose Metabolism Disorders · Metabolic Disease

  • NCT05564039Phase 4Completed282 enrolled2022

    A Study of Tirzepatide (LY3298176) in Adult Participants With Type 2 Diabetes Switching From Dulaglutide (SURPASS-SWITCH)

    Eli Lilly and Company

    Type 2 Diabetes

  • NCT05582096Phase 1Completed38 enrolled2022

    A Study of LY3457263 in Obese Participants

    Eli Lilly and Company

    Overweight · Obesity

  • NCT05556512Phase 3Active Not Recruiting15,374 enrolled2022

    A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity

    Eli Lilly and Company

    Obesity · Overweight

  • NCT05766358Completed27 enrolled2022

    Role Of Metabolic Adaptation In Weight Regain

    Pennington Biomedical Research Center

    Weight Loss · Weight Gain · Obesity

  • NCT05433584Phase 4Active Not Recruiting780 enrolled2022

    A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes

    Eli Lilly and Company

    Type 2 Diabetes

  • NCT05412004Phase 3Completed469 enrolled2022

    Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstructive Sleep Apnea

    Eli Lilly and Company

    Obstructive Sleep Apnea · Obesity

  • NCT05260021Phase 3Completed99 enrolled2022

    A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both

    Eli Lilly and Company

    Type2 Diabetes · Diabetes Mellitus · Diabetes Mellitus, Type 2 · T2D

  • NCT05553093Phase 4Recruiting150 enrolled2022

    Effects of Tirzepatide and Insulin Glargine on Glucolipid Metabolism and Brain Function in Patients With Type 2 Diabetes

    Nanjing First Hospital, Nanjing Medical University

    Type 2 Diabetes Mellitus

  • NCT05024032Phase 3Completed210 enrolled2021

    A Study of Tirzepatide (LY3298176) in Chinese Participants Without Type 2 Diabetes Who Have Obesity or Overweight (SURMOUNT-CN)

    Eli Lilly and Company

    Obesity · Overweight · Metabolism and Nutrition Disorder

  • NCT04844918Phase 3Completed267 enrolled2021

    A Study of Tirzepatide (LY3298176) in Participants With Obesity Disease

    Eli Lilly and Company

    Obesity

  • NCT04847557Phase 3Completed731 enrolled2021

    A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial

    Eli Lilly and Company

    Obesity · Heart Failure With Preserved Ejection Fraction (HFpEF)

  • NCT04657016Phase 3Completed579 enrolled2021

    A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program

    Eli Lilly and Company

    Obesity · Overweight

  • NCT04657003Phase 3Completed938 enrolled2021

    A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight

    Eli Lilly and Company

    Type 2 Diabetes · Overweight · Obesity

  • NCT04660643Phase 3Completed783 enrolled2021

    A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss

    Eli Lilly and Company

    Obesity · Overweight

  • NCT04235959Phase 1Completed24 enrolled2020

    A Study of Tirzepatide in Chinese Participants With Type 2 Diabetes Mellitus

    Eli Lilly and Company

    Diabetes Mellitus, Type 2

  • NCT04537923Phase 3Completed1,428 enrolled2020

    A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin

    Eli Lilly and Company

    Type 2 Diabetes

  • NCT04407234Phase 1Completed36 enrolled2020

    A Study to Measure Stomach Emptying in Overweight Non-diabetic and Diabetic Participants Using Tirzepatide

    Eli Lilly and Company

    Overweight · Obesity · Diabetes Mellitus, Type 2

  • NCT04311411Phase 1Completed114 enrolled2020

    A Study of Tirzepatide in Overweight and Very Overweight Participants

    Eli Lilly and Company

    Obesity · Overweight

  • NCT04311424Phase 1Completed6 enrolled2020

    Study of Tirzepatide in Healthy Participants

    Eli Lilly and Company

    Healthy

  • NCT04081337Phase 1Completed55 enrolled2020

    A Study to Measure Energy Expenditure and Food Intake in Participants With Obesity Using Tirzepatide

    Eli Lilly and Company

    Obesity

  • NCT04255433Phase 3Completed13,299 enrolled2020

    A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

    Eli Lilly and Company

    Type 2 Diabetes Mellitus

  • NCT04172987Phase 1Completed40 enrolled2020

    A Study of the Effect of Tirzepatide on How the Body Handles Birth Control Pills in Healthy Female Participants

    Eli Lilly and Company

    Healthy

  • NCT04050553Phase 1Completed42 enrolled2020

    A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus

    Eli Lilly and Company

    Diabetes Mellitus, Type 2 · Hypoglycemia

  • NCT04093752Phase 3Completed917 enrolled2019

    A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes on Metformin With or Without Sulfonylurea (SURPASS-AP-Combo)

    Eli Lilly and Company

    Type 2 Diabetes

  • NCT04184622Phase 3Completed2,539 enrolled2019

    A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight

    Eli Lilly and Company

    Overweight · Obesity

  • NCT04166773Phase 2Completed190 enrolled2019

    A Study of Tirzepatide (LY3298176) in Participants With Nonalcoholic Steatohepatitis (NASH)

    Eli Lilly and Company

    Nonalcoholic Steatohepatitis

  • NCT04050670Phase 1Completed54 enrolled2019

    A Study of Tirzepatide at Different Injection Sites in Participants With Different Body Sizes

    Eli Lilly and Company

    Healthy

  • NCT04039503Phase 3Completed475 enrolled2019

    A Study of Tirzepatide (LY3298176) Versus Placebo in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine With or Without Metformin

    Eli Lilly and Company

    Type 2 Diabetes

  • NCT04004988Phase 1Completed47 enrolled2019

    A Study of Tirzepatide Administered by Two Different Devices in Healthy Participants

    Eli Lilly and Company

    Healthy

  • NCT03987919Phase 3Completed1,879 enrolled2019

    A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes

    Eli Lilly and Company

    Type 2 Diabetes

  • NCT03940742Phase 1Completed32 enrolled2019

    A Study of Tirzepatide in Participants With Impaired Liver Function

    Eli Lilly and Company

    Hepatic Insufficiency

  • NCT03951753Phase 1Completed117 enrolled2019

    A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus (T2DM)

    Eli Lilly and Company

    Diabetes Mellitus, Type 2

  • NCT03954834Phase 3Completed478 enrolled2019

    A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Not Controlled With Diet and Exercise Alone

    Eli Lilly and Company

    Type 2 Diabetes Mellitus

  • NCT03861052Phase 3Completed636 enrolled2019

    A Study of Tirzepatide (LY3298176) Compared to Dulaglutide in Participants With Type 2 Diabetes

    Eli Lilly and Company

    Type 2 Diabetes

  • NCT03882970Phase 3Completed1,444 enrolled2019

    A Study of Tirzepatide (LY3298176) Versus Insulin Degludec in Participants With Type 2 Diabetes

    Eli Lilly and Company

    Type 2 Diabetes Mellitus

  • NCT03861039Phase 3Completed443 enrolled2019

    A Long-term Safety Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes

    Eli Lilly and Company

    Type 2 Diabetes Mellitus

  • NCT03730662Phase 3Completed2,002 enrolled2018

    A Study of Tirzepatide (LY3298176) Once a Week Versus Insulin Glargine Once a Day in Participants With Type 2 Diabetes and Increased Cardiovascular Risk

    Eli Lilly and Company

    Type 2 Diabetes Mellitus

  • NCT03482024Phase 1Completed45 enrolled2018

    A Study of Tirzepatide (LY3298176) in Participants With Impaired Kidney Function

    Eli Lilly and Company

    Renal Insufficiency · End Stage Renal Disease

  • NCT03375463Phase 1Completed52 enrolled2017

    A Study of Tirzepatide (LY3298176) in Healthy Participants

    Eli Lilly and Company

    Healthy

  • NCT03322631Phase 1Completed48 enrolled2017

    A Study of Tirzepatide (LY3298176) in Japanese Participants With Type 2 Diabetes

    Eli Lilly and Company

    Type 2 Diabetes Mellitus

  • NCT03311724Phase 2Completed111 enrolled2017

    A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes

    Eli Lilly and Company

    Type 2 Diabetes

  • NCT03131687Phase 2Completed318 enrolled2017

    A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Mellitus

    Eli Lilly and Company

    Type 2 Diabetes Mellitus

  • NCT02759107Phase 1Completed142 enrolled2016

    A Study of Tirzepatide (LY3298176) in Healthy Participants and Participants With Type 2 Diabetes (T2DM)

    Eli Lilly and Company

    Healthy · Type 2 Diabetes Mellitus (T2DM)

  • 2022-501106-35-00Revoked143 enrolled

    17203

    Eli Lilly & Co.

    Obesity Overweight

  • 2025-523877-40-00Authorised, Not Started78 enrolled

    CRC.0007

    University College Dublin

    Endometrial adenocarcinoma

  • 2026-525500-10-00Authorised, Not Started345 enrolled

    SAMUEL

    Institut De Recerca Biomedica De Lleida Fundacio Dr. Pifarre

    Obstructive sleep apnea syndrome, Obesity

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

  • 2026-526044-12-00Authorised, Not Started40 enrolled

    Efficacy and safety of pharmacological therapy of obesity in liver transplant candidates

    Institute For Clinical And Experimental Medicine

    Obesity

    Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.

Sources: ClinicalTrials.gov, the EU Clinical Trials Information System and ISRCTN, deduplicated so a study registered in more than one registry is counted once. A study is listed when Tirzepatide is named as an intervention. A registered trial is a plan, not a result — registration says nothing about whether the peptide worked.