Clinical trials
Every registered trial of Survodutide
49 studies, 6 still enrolling.
Plain-Language Summary
Plain-language reading of the public trial registries.
In short
- Survodutide has a real but limited body of human research.
- 49 registered studies in total.
- 6 are still enrolling people, so this is active research, not just history.
What kind of research
- 49 studies actually gave the peptide to volunteers and measured what happened. This is the kind of study that can show whether something works.
- About 17,065 people took part in those.
How far along it is
- 9 trials have reached phase 3 or 4 — the large, late-stage trials regulators rely on to approve a drug.
- 12 have published results in the medical literature that anyone can read.
- The research spans 46 countries.
A registered trial is a plan, not a result. Registration means a study was declared in advance; it says nothing about whether the peptide worked, and a trial can be registered and then abandoned.
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Showing 49 of 49 trials for Survodutide.
A Study to Compare How 2 Different Formulations of Survodutide Are Taken up in the Body When Given by Injection in Healthy Men and Women With and Without Overweight or Obesity
Boehringer Ingelheim
Healthy · Obesity
A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
Boehringer Ingelheim
Type 2 Diabetes
A Study in People With Overweight or Obesity to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body
Boehringer Ingelheim
Healthy · Obesity · Overweight
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Study in Healthy People or Otherwise Healthy With Overweight or Obesity to Compare 2 Formulations of Survodutide Given in Different Ways, Either as a Pre-filled Syringe or a Pen-like Injector
Boehringer Ingelheim
Healthy · Obesity
Albuminuria Reduction Study With Survodutide Treatment in Kidney Disease
University Medical Center Groningen
Chronic Kidney Disease
1404-0015
Boehringer Ingelheim International GmbH
Healthy volunteer trial
A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body
Boehringer Ingelheim
Healthy
1404-0103
Boehringer Ingelheim International GmbH
Healthy volunteer trial
A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up in the Body
Boehringer Ingelheim
Healthy
1404-0099
Boehringer Ingelheim International GmbH
Healthy volunteer trial
A Study to Test Whether Survodutide Improves How the Body Uses Energy and Breaks Down Fat in People With Obesity
Boehringer Ingelheim
Obesity
A Study in Healthy People to Compare How 3 Different Formulations of Survodutide Are Taken up in the Body
Boehringer Ingelheim
Healthy
1404-0074
Boehringer Ingelheim International GmbH
Healthy volunteer trial
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
Boehringer Ingelheim
Metabolic Dysfunction Associated Steatohepatitis
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
Boehringer Ingelheim
Metabolic Dysfunction Associated Steatohepatitis (MASH) · Liver Fibrosis
A Study to Test Whether BI 456906 (Survodutide) Influences the Amount of Bupropion, Caffeine and Midazolam in the Blood in People With Overweight or Obesity
Boehringer Ingelheim
Overweight · Obesity
A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver
Boehringer Ingelheim
Obesity
14040047
Boehringer Ingelheim International GmbH
No targeted indication. Male and female subjects with obesity.
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
1404-0008
Boehringer Ingelheim International GmbH
Overweight, Obesity
A Study in Chinese People With Overweight or Obesity to Test How Different Doses of Survodutide Are Taken up in the Body
Boehringer Ingelheim
Overweight · Obesity
1404-0056
Boehringer Ingelheim International GmbH
Obesity
A Study to Test How BI 456906 is Taken up in the Blood of People With and Without Kidney Problems
Boehringer Ingelheim
Healthy · Renal Impairment
1404-0009
Boehringer Ingelheim International GmbH
Renal impairment (mild, moderate and severe), Healthy
A Study in People With Overweight or Obesity to Test How BI 1820237, BI 456906, or a Combination of Both Affects Brain Activity
Boehringer Ingelheim
Obesity
1458-0006
Boehringer Ingelheim International GmbH
Obesity
A Study to Test Whether Survodutide Helps People Living With Obesity or Overweight and With a Confirmed or Presumed Liver Disease Called Non-alcoholic Steatohepatitis (NASH) to Reduce Liver Fat and to Lose Weight (SYNCHRONIZE-MASLD)
Boehringer Ingelheim
Obesity · Non-Alcoholic SteatoHepatitis (NASH)
A Study to Test Whether Multiple Doses of BI 456906 Have an Effect on Cardiac Safety in People With Overweight or Obesity
Boehringer Ingelheim
Overweight · Obesity
A Study to Test Whether Survodutide (BI 456906) Helps Chinese People Living With Overweight or Obesity to Lose Weight
Boehringer Ingelheim
Obesity · Overweight
1404-0038
Boehringer Ingelheim International GmbH, Boehringer Ingelheim RCV GmbH & Co. KG
Obesity
1404-0041
Boehringer Ingelheim International GmbH, Boehringer Ingelheim RCV GmbH & Co. KG, Boehringer Ingelheim Espana S.A.
Obesity, Diabetes mellitus type II
A Study to Test Whether Survodutide Helps Japanese People Living With Obesity Disease
Boehringer Ingelheim
Obesity
1404-0040
Boehringer Ingelheim International GmbH, Boehringer Ingelheim Espana S.A., Boehringer Ingelheim RCV GmbH & Co. KG
Obesity
A Study in Women With Overweight or Obesity to Test Whether Different Doses of BI 456906 Influence the Amount of a Contraceptive in the Blood
Boehringer Ingelheim
Healthy
1404-0014
Boehringer Ingelheim International GmbH
pharmacokinetic trial
A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight
Boehringer Ingelheim
Obesity · Diabetes Mellitus, Type 2
A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who do Not Have Diabetes to Lose Weight
Boehringer Ingelheim
Obesity
A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)
Boehringer Ingelheim
Obesity
A Study in People With Overweight or Obesity to Test How Well Different Doses of BI 1820237 Are Tolerated When Given Alone or in Combination With Either Semaglutide or BI 456906
Boehringer Ingelheim
Healthy · Obesity
A Study in Healthy Men to Test How BI 456906 is Processed in the Body
Boehringer Ingelheim
Healthy
A Study to (1) Compare How BI 456906 is Taken up in the Body of Healthy People and People With Liver Problems and (2) Find Out How People With Overweight and Obesity, With and Without Liver Problems, Tolerate Different Doses of BI 456906
Boehringer Ingelheim
Healthy · Liver Diseases · Obesity
A Study to Test Safety and Efficacy of Survodutide (BI456906) in Adults With Non-alcoholic Steatohepatitis (NASH) and Fibrosis (F1-F3)
Boehringer Ingelheim
Non-alcoholic Steatohepatitis (NASH)
A Study to Test Whether Different Doses of BI 456906 Help People With Overweight or Obesity to Lose Weight
Boehringer Ingelheim
Obesity
A Study to Test How Different Doses of BI 456906 Are Tolerated in Japanese Men With a Body Mass Index (BMI) Between 23 and 40 kg/m2
Boehringer Ingelheim
Healthy
A Study to Test Whether Different Doses of BI 456906 Are Effective in Treating Adults With Type 2 Diabetes.
Boehringer Ingelheim
Diabetes Mellitus, Type 2
A Study to Test Different Doses of BI 456906 in Patients With Obesity
Boehringer Ingelheim
Obesity
Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 456906 in Healthy Male Volunteers
Boehringer Ingelheim
Healthy
22774
Universitair Medisch Centrum Groningen
Chronic Kidney Disease
1404-0145
Boehringer Ingelheim International GmbH
Healthy
1404-0118
Boehringer Ingelheim International GmbH
Healthy volunteer trial
Sources: ClinicalTrials.gov, the EU Clinical Trials Information System and ISRCTN, deduplicated so a study registered in more than one registry is counted once. A study is listed when Survodutide is named as an intervention. A registered trial is a plan, not a result — registration says nothing about whether the peptide worked.