Plain-Language Summary
Plain-language reading of the public trial registries.
In short
- Very little human research on Macimorelin has been registered.
- 5 registered studies in total.
- None are currently enrolling — this research has already happened.
What kind of research
- 5 studies actually gave the peptide to volunteers and measured what happened. This is the kind of study that can show whether something works.
- About 402 people took part in those.
How far along it is
- 3 trials have reached phase 3 or 4 — the large, late-stage trials regulators rely on to approve a drug.
- 4 have published results in the medical literature that anyone can read.
- The research spans 16 countries.
A registered trial is a plan, not a result. Registration means a study was declared in advance; it says nothing about whether the peptide worked, and a trial can be registered and then abandoned.
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Showing 5 of 5 trials for Macimorelin.
A Research Study of How Well Macimorelin Works to Find Out if Children Have a Lack of Growth Hormone and How Safe it is
AEterna Zentaris
Growth Hormone Deficiency
Copeptin After an Oral Stimulation With Macimorelin in Healthy Volunteers
University Hospital, Basel, Switzerland
Polyuria-polydipsia Syndrome
Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency
AEterna Zentaris
Growth Hormone Deficiency With Pituitary Anomalies
Pilot Clinical Trial of Repeated Doses of Macimorelin to Assess Safety and Efficacy in Patients With Cancer Cachexia
Garcia, Jose M., MD, PhD
Cancer Cachexia
Investigation of a New, Oral Growth Hormone Secretagogue, AEZS-130 as a Growth Hormone Stimulation Test.
AEterna Zentaris
Diagnosis of Adult Growth Hormone Deficiency (AGDH)
Sources: ClinicalTrials.gov, the EU Clinical Trials Information System and ISRCTN, deduplicated so a study registered in more than one registry is counted once. A study is listed when Macimorelin is named as an intervention. A registered trial is a plan, not a result — registration says nothing about whether the peptide worked.