Clinical trials
Every registered trial of Leuprolide
464 studies, 58 still enrolling.
Plain-Language Summary
Plain-language reading of the public trial registries.
In short
- Leuprolide has been studied in people a great deal.
- 464 registered studies in total.
- 58 are still enrolling people, so this is active research, not just history.
What kind of research
- 424 studies actually gave the peptide to volunteers and measured what happened. This is the kind of study that can show whether something works.
- About 87,747 people took part in those.
- A further 40 studies only looked at records of people already taking it. These are counted separately because nobody was given the peptide for the study, so they cannot prove cause and effect.
How far along it is
- 157 trials have reached phase 3 or 4 — the large, late-stage trials regulators rely on to approve a drug.
- 108 have published results in the medical literature that anyone can read.
- The research spans 62 countries.
A registered trial is a plan, not a result. Registration means a study was declared in advance; it says nothing about whether the peptide worked, and a trial can be registered and then abandoned.
Filter
Showing 464 of 464 trials for Leuprolide.
QL1706 Plus Neoadjuvant Endocrine Therapy in HR-Positive/HER2-Negative Breast Cancer With a Poor Response to Neoadjuvant Chemotherapy
Hebei Medical University Fourth Hospital
Breast Cancer
Clinical Trial Evaluating the Biological Activity of a New Drug Identified as Prifetrastat (PF-07248144), Combined With Fulvestrant for the Treatment of Patients With Hormone Receptor Positive (HR+) and HER2 Negative (HER2-) Breast Cancer Extended to Other Organs.
UNICANCER
Metastatic (Stage IV) Melanoma
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
BRE-06: Study to Increase Tolerance to Aromatase Inhibitors for Patients With Early-Stage Hormone Receptor Positive Breast Cancer Who Developed Hypoactive Sexual Desire Disorder
University of Illinois at Chicago
Early-stage Breast Cancer · Hypoactive Sexual Desire Disorder · Hormone Receptor Positive Breast Carcinoma · Breast Cancer
Phase Ia Trial of HHK001 Compared With Enantone in Patients With Endometriosis
Zhuhai Huahaikang Pharmaceutical Technology Co., Ltd.
Endometriosis
A Study of Leuprorelin 1-Month (4-Week) Formulation in Children With Central Precocious Puberty
LG Chem
Central Precocious Puberty
Tolerability of Dalpiciclib vs. Abemaciclib/Ribociclib in Early HR+/HER2- Breast Cancer
Henan Cancer Hospital
Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Efficacy and Safety of Darolutamide Combined With Docetaxel and ADT as Neoadjuvant Therapy for Locally Advanced Prostate Cancer.
RenJi Hospital
Prostate Cancer · Prostate · Prostate Cancer Patients
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT
Baptist Health South Florida
Prostate Cancer · Localized Prostate Carcinoma
Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial
Mayo Clinic
Recurrent Prostate Adenocarcinoma · Stage IVB Prostate Cancer AJCC v8 · Castration-Sensitive Prostate Cancer · Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Impact of Formulation Change on Ovarian Suppression in Young Breast Cancer Patients.
Fudan University
Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Risk Prostate Cancer
Icahn School of Medicine at Mount Sinai
Prostate Cancer · High-risk Prostate Cancer
Study of Recurrence-directed Therapy (RDT) With or Without Androgen-Deprivation Therapy (ADT) In Patients With Radio-recurrent Oligo-metastatic Hormone/Castrate Sensitive Prostate Cancer (romCSPC)
Ontario Clinical Oncology Group (OCOG)
Prostate Adenocarcinoma · Castration Sensitive Prostate Cancer
Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Metastatic Castration-resistant Prostate Cancer
Rezvilutamide for High-Risk Prostate Cancer After Surgery
Fujian Medical University Union Hospital
Prostate Cancer (Adenocarcinoma)
Fulvestrant With Ribociclib Versus Physician's Choice Treatments Recurred After Completion of Adjuvant Cyclin-Dependent Kinase 4/6 Inhibitors in HR+, HER2- Metastatic Breast Cancer
Yeon Hee Park
Breast Cancer Metastatic
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Safety and Preliminary Efficacy Evaluation of LC-K76 Plus Anti-PD-1 Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Shanghai Changzheng Hospital
mCRPC
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Safety and Efficacy Evaluation of LC-K76 in Patients With Metastatic Hormone-Sensitive Prostate Cancer
Shanghai Changzheng Hospital
mHSPC · mHNPC · Prostate Cancer Adenocarcinoma
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial
University of Michigan Rogel Cancer Center
Anatomic Stage I Breast Cancer AJCC v8 · Anatomic Stage II Breast Cancer AJCC v8 · Anatomic Stage III Breast Cancer AJCC v8 · Anatomic Stage IV Breast Cancer AJCC v8
Phase II Trial of PSA Response-based Androgen Deprivation Therapy and Nodal Coverage for Prostate Cancer Early Salvage Radiotherapy (RANGER)
University of Texas Southwestern Medical Center
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Short-term Preoperative, Evaluating Activity and Safety of Elacestrant Monotherapy as Compared to Elacestrant + Ovarian Function Suppression (LHRH Agonist) in Premenopausal Patients With Stage I-II ER+/HER2- Breast Cancer
Gustave Roussy, Cancer Campus, Grand Paris
Breast Cancer
CSET 2025/4053
Institut Gustave Roussy
Breast cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Maintenance Therapy in HER2-Positive Unresectable Locally Recurrent or Metastatic Breast Cancer: A Phase II Study
Fudan University
HER2-positive Breast Cancer
The COSMYC Trial (COmbined Suppression of MYC)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Metastatic Castration-resistant Prostate Cancer
Trial Evaluating the Safety and Efficacy Of MR-Linac-Guided Radiotherapy as Salvage Treatment After External Beam Radiotherapy Recurrence (TUMORNATOR II)
NYU Langone Health
Intraprostatic Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Norethindrone Impact on Receptiva Outcomes
Inception Fertility Research Institute, LLC
Infertility (IVF Patients) · Infertility Female
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer
The Methodist Hospital Research Institute
Prostate Cancer (Adenocarcinoma)
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Exploration of Treatment Effect of Novel Hormone Therapy Combined With Local Treatment Based on PSMA PET/CT Evaluation in mHSCP Patients
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Prostate Cancer Metastatic Disease
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Cardiovascular Health of Transgender Individuals During the Gender-affirming Pathway
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Gender Incongruence · Cardiovascular (CV) Risk · Cardiovascular Disease Risk Factor · Cardiovascular Disease Acute
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Clinical Study of KLH-2109 in Patients With Endometriosis
Kissei Pharmaceutical Co., Ltd.
Endometriosis
Pembrolizumab With Androgen Deprivation Therapy and Radiotherapy for the Treatment of Patients With High Risk Localized Prostate Cancer
OHSU Knight Cancer Institute
High Risk Prostate Carcinoma · Localized Prostate Adenocarcinoma · Stage I Prostate Cancer AJCC v8 · Stage II Prostate Cancer AJCC v8
Optimal Duration of Hormonal Therapy for Unfavorable Intermediate-risk Prostate Cancer Patients: 6 Versus 12 Months.
Charles LeMoyne Hospital
Prostate Cancer (Adenocarcinoma)
COACTION Trial - COmbination Androgen bloCkade in inTermediate to hIgh-risk prOstate caNcer
Brazilian Clinical Research Institute
Prostate Cancer
REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial
Emory University
Recurrent Prostate Carcinoma · Stage III Prostate Cancer AJCC v8 · Stage IVA Prostate Cancer AJCC v8
Adaptive Androgen Deprivation and Docetaxel in Metastatic Castration Sensitive Prostate Cancer
H. Lee Moffitt Cancer Center and Research Institute
Metastatic Castration Sensitive Prostate Cancer
Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer
Roswell Park Cancer Institute
Castration-Resistant Prostate Carcinoma · Metastatic Prostate Carcinoma · Stage IVB Prostate Cancer AJCC v8
Efficacy and Safety of Leuprolide Acetate 45 mg in Subjects With Central Precocious Puberty
HanAll BioPharma Co., Ltd.
CPP
A Comparative Dose-finding Study of RS-113 in Patients With Metastatic Castration-resistant Prostate Cancer
R-Pharm International, LLC
Metastatic Castration-resistant Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Adjuvant Rezvilutamide in Combination With Androgen Deprivation Therapy in Androgen Receptor-positive, High-risk Salivary Duct Carcinoma
Peking University First Hospital
Salivary Gland Neoplasm Duct
Evaluating Tibolone Add-back in Patients With Endometriosis and Fibroids
McGill University Health Centre/Research Institute of the McGill University Health Centre
Endometriosis · Fibroids
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
ESTRACISE
Central Finland Hospital District Central Finland Hospital Nova
Prostate cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients
National Taiwan University Hospital
Triple Negative Breast Cancer · Premenopausal Breast Cancer
Safety, Efficacy and Pharmacokinetic Behavior of Leuprolide Injectable Emulsion for Premenopausal Breast Cancer Subjects.
Changchun GeneScience Pharmaceutical Co., Ltd.
Breast Cancer Subjects
Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer
Ohio State University Comprehensive Cancer Center
Prostate Adenocarcinoma · Stage IIB Prostate Cancer AJCC v8 · Stage IIC Prostate Cancer AJCC v8
ADENOFERT
Azienda Ospedaliero Universitaria Di Modena
women with transvaginal ultrasound (TV-US)-based diagnosis of adenomyosis, women without adenomyosis but with similar baseline reproductive risks
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
RT2019-13
Universitair Medisch Centrum Groningen
Patients with biochemical recurrence after primary treatment of prostate cancer presenting with =<4 metastases
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial
Mayo Clinic
Recurrent Castration-Sensitive Prostate Carcinoma · Recurrent Prostate Cancer · Castration-resistant Prostate Cancer · Biochemically Recurrent Prostate Carcinoma
A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss
VA Office of Research and Development
High-Risk Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Efficacy and Safety of DKF-MA102 in Patients With Prostate Cancer
Dongkook Pharmaceutical Co., Ltd.
Advanced Prostate Cancer
A Study of Avutometinib, Defactinib, and Letrozole in People With Low-Grade Serous Ovarian Cancer
Memorial Sloan Kettering Cancer Center
Low-Grade Serous Ovarian Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer
NYU Langone Health
Prostate Cancer
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
Novartis Pharmaceuticals
Early Breast Cancer
RecoverPC: Relugolix vs GnRH Agonist in Quality of Life
Dana-Farber Cancer Institute
Prostate Cancer · Prostatic Neoplasms
Study to Test the Drug Darolutamide Along With the Drugs Leuprolide Acetate and Exemestane in Patients With Recurrent Ovarian Granulosa Cell Tumors
National Cancer Institute (NCI)
Adult Ovarian Granulosa Cell Tumor
Apa/Enza short study (Shortened 12 months duration of androgen receptor signalling agent in combination with androgen deprivation therapy in patients with low-volume metastatic castration-sensitive prostate cancer: a randomized nationwide trial
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
low-volume metastatic castration-sensitive prostate cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
CO44657
F. Hoffmann-La Roche AG
Estrogen receptor (ER)-positive, HER2-negative advanced breast cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Neoadjuvant Study of Abiraterone Acetate, Leuprolide Acetate, and Belzutifan in Men With Regional Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Cancer
Treatment of High-Risk Prostate Cancer Guided by Novel Diagnostic Radio- and Molecular Tracers
Cancer Research Antwerp
Prostate Cancer
Intermittent Darolutamide Treatment in the Triple Therapy of mHSPC
The First Affiliated Hospital with Nanjing Medical University
Metastatic Prostate Cancer · Intermitent Anti-androgen Therapy
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Study on the Efficacy of Androgen Deprivation Therapy Combined With Anti-PD-1 Therapy in Advanced Lung Cancer
Jinzhou Medical University
NSCLC, Stage III · NSCLC, Stage IV
Detection of Tumor DNA in the Blood of Patients Receiving Standard Therapy for Hormone Receptor-positive (HR+) Non-HER2 Expressing (HER2-) Metastatic Breast Cancer as a Tool to Select Those Who May Benefit From the Next Course of Fulvestrant in Combination With Alpelisib or Ribociclib
UNICANCER
Breast Cancer Stage IV
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Cancer
Contributions to Hypertension With Androgen Deprivation Therapy
University of Colorado, Denver
Androgen Deprivation Therapy · Prostate Cancer · Hypertension · Autonomic Dysfunction
Comparing the Safety and Efficacy in the Use of Hormonal Therapy on Endometriosis Patients After Conservative Surgery
Universitas Diponegoro
Endometriosis Ovary
The Benefits of Continued Use of Ovarian Function Suppression After 5 Years
Hongmei Zheng, PhD
Breast Cancer Female · Endocrine Therapy
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Precision Treatment of Recurrent/Metastatic Salivary Gland Carcinoma Guided by Molecular Typing
Peking Union Medical College
Salivary Gland Carcinoma · Precision Therapy
Neo-DAB: Darolutamide and Abemaciclib in Prostate Cancer
Praful Ravi, MB BCHir, MRCP
Metastatic Prostate Cancer · Non-metastatic Prostate Cancer · Prostate Cancer
Evaluate the Efficacy and Safety of DWJ108J
Daewoong Pharmaceutical Co. LTD.
Central Precocious Puberty
A Phase II Study of Advanced Salivary Gland Carcinoma Based on Molecular Typing
Fudan University
Advanced Salivary Gland Carcinoma
Testing the Anti-cancer Drug Darolutamide in Patients With Testosterone-Driven Salivary Gland Cancers
National Cancer Institute (NCI)
Locally Advanced Salivary Gland Carcinoma · Metastatic Salivary Gland Carcinoma · Recurrent Salivary Gland Carcinoma · Unresectable Salivary Gland Carcinoma
Chidamide/Everolimus for PIK3CA Wild-type/Mutant HR+/HER2- Advanced Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
HR+/HER2- Advanced Breast Cancer · Targeted Therapy
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Efficacy, Safety, and Pharmacokinetics of Leuprolide Mesylate in Subjects With Central Precocious Puberty
Foresee Pharmaceuticals Co., Ltd.
Puberty; Precocious, Central
Efficacy and Safety of Fluzoparib Combined With Adjuvant Endocrine Therapy for HR+/HER2- SNF3-subtype Early Breast Cancer (BCTOP-L-A01)
Fudan University
Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Comparative Evaluation of Efficacy and Safety of Toremifene, Tamoxifen, and Aromatase Inhibitor Plus Ovarian Function Suppression in Hormone Receptor-Positive Early Breast Cancer Among Non-Low-Risk Premenopausal Women: A Real-World Study
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hormone-receptor-positive Breast Cancer · Premenopausal Breast Cancer · Breast Cancer Patients at Intermediate to High Risk · Ovarian Function Suppression Combined With Aromatase Inhibitor or Tamoxifen or Torimefen
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Comparison of the Therapeutic Effects of Vaginal Repair With Leuprorelin and Vaginal Repair in the Treatment of Cesarean Section Scar Defect
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Cesarean Section; Dehiscence
Adenomyosis and ART
Azienda Ospedaliero-Universitaria di Modena
Adenomyosis
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Study of Leuprolide Acetate Depot in Children With Central Precocious Puberty
Takeda
Central Precocious Puberty
ENHANCE
Institut Mutualiste Montsouris
Intermediate risk prostate cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Impact of Hormonal Therapy on Prostate Cancer Recurrence After Radical Prostatectomy
Ottawa Hospital Research Institute
Prostate Cancer
Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Systemic Lupus Erythematosus (Sle) · Primary Ovarian Insufficiency (Poi)
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Multicenter Open-label Clinical Study on the Prevention of Premature Ovarian Failure After HSCT
First Affiliated Hospital Xi'an Jiaotong University
Hematopoietic Stem Cell Transplantation · Premature Ovarian Failure
Real World Evidence Study on Metastatic Prostate Cancer in the Pirkanmaa Hospital District in Finland
Pfizer
Metastatic Castration Sensitive Prostate Cancer (mCSPC) · Metastatic Castration Resistant Prostate Cancer (mCRPC)
OFS in Premenopausal Node+ Breast Cancer With Low Genomic Risk
Gangnam Severance Hospital
Breast Cancer · Estrogen Receptor Positive Tumor · HER2-negative Breast Cancer · Premenopausal Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Kisspeptin Administration Subcutaneously to Patients With IHH
Stephanie B. Seminara, MD
Hypogonadotropic Hypogonadism
Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations
Rana McKay, MD
Prostate Cancer · BRCA1 Mutation · BRCA2 Mutation · Prostatic Adenocarcinoma
Randomized Study to Evaluate MACE in Patients With Prostate Cancer Treated With Relugolix or Leuprolide Acetate
Sumitomo Pharma America, Inc.
Prostate Cancer
Adaptive Stereotactic Body Radiation Therapy to the Prostate and Pelvic Nodes With Simultaneous Integrated Boost to the MR-detected Nodule for Patients With High-risk and Unfavorable Intermediate-risk Prostate Cancer
Washington University School of Medicine
Prostate Cancer · Cancer of the Prostate
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Safety Extension Study for Subjects With HR+, HER2- Breast Cancer for Subjects Who Have Completed the OVELIA Study
Tolmar Inc.
Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Drug-Drug Interaction Study in Trans Women Living With HIV
Maple Leaf Research
Hiv · Transgenderism
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM)
Alliance for Clinical Trials in Oncology
Castration-Sensitive Prostate Carcinoma · Metastatic Prostate Carcinoma · Stage IV Prostate Cancer AJCC v8 · Stage IVA Prostate Cancer AJCC v8
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia
Kissei Pharmaceutical Co., Ltd.
Uterine Fibroids (MeSH Heading: Leiomyoma)
Assessing Ketorolac (Toradol) at Oocyte Retrieval
Shady Grove Fertility Reproductive Science Center
Infertility · Infertility, Female · Oocyte Retrieval · Postoperative Pain
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
The Study Will Evaluate if Leuprolide Mesylate is Safe and Effective in the Treatment of Subjects With Advanced Prostate Carcinoma, When Administered as Two Injections Six Months Apart.
Changchun GeneScience Pharmaceutical Co., Ltd.
Advanced Prostate Cancer
RElugolix VErsus LeUprolide Cardiac Trial
Emory University
Biochemically Recurrent Prostate Carcinoma · Localized Prostate Carcinoma · Stage I Prostate Cancer AJCC v8 · Stage II Prostate Cancer AJCC v8
A GnRH Agonist IN Pre-menopausal Women STudy to Treat Severe Polycystic Liver Disease
University Medical Center Groningen
Polycystic Liver Disease · Autosomal Dominant Polycystic Kidney
Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate Cancer
Fudan University
Prostate Cancer
Study to Evaluate the Pharmacodynamics and Efficacy of Leuprolide Tablets (Ovarest®) in Women With Endometriosis
Enteris BioPharma Inc.
Endometriosis
RWE About QOL and Compliance of Patients With OFS in China
Fudan University
Breast Cancer · Quality of Life · Hormone Receptor-positive Breast Cancer
First Strike, Second Strike Therapies for High Risk Metastatic Castration Sensitive Prostate Cancer
H. Lee Moffitt Cancer Center and Research Institute
Prostate Cancer · Stage IV Prostate Cancer
A Study Called AWARENESS Using Data From Men in Alberta to Observe Treatment Patterns for Metastatic Castration-sensitive Prostate Cancer
Bayer
Metastatic Castration-sensitive Prostate Cancer
Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial
NRG Oncology
Prostate Adenocarcinoma
A Study of Shorter Course Hormone Therapy and Radiation for High-risk Prostate Cancer
Memorial Sloan Kettering Cancer Center
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy
Alliance for Clinical Trials in Oncology
Castration-Resistant Prostate Carcinoma · Metastatic Prostate Adenocarcinoma · Stage IV Prostate Cancer AJCC v8 · Stage IVA Prostate Cancer AJCC v8
Trastuzumab + Alpelisib +/- Fulvestrant vs Trastuzumab + CT in Patients With PIK3CA Mutated Previously Treated HER2+ Advanced BrEasT Cancer (ALPHABET)
Spanish Breast Cancer Research Group
Advanced Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Exploratory Study of Molecular Profile-Associated Evidence Guided Precision Therapy for Salivary Gland Cancer（MAPS）
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Salivary Gland Neoplasms
Leuprolide Acetate 3.75 mg Depot Injection for Patients With Advanced Prostate Cancer
Bharat Serums and Vaccines Limited
Advanced Prostate Adenocarcinoma
Ovarian Suppression Evaluating Subcutaneous Leuprolide Acetate in Breast Cancer
Tolmar Inc.
Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Psychological Impact of Amenorrhea in Women With Endometriosis
University of Cagliari
Amenorrhea · Endometriosis · Quality of Life
Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer
City of Hope Medical Center
Castration-Sensitive Prostate Carcinoma · Metastatic Prostate Adenocarcinoma · Stage IV Prostate Cancer AJCC v8 · Stage IVA Prostate Cancer AJCC v8
Efficacy and Safety of Leuprorelin 3M in Premenopausal Women With Hormone Receptor-positive Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hormone Receptor-positive Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Antiandrogen Therapy and SBRT in Treating Patients With Recurrent, Metastatic Prostate Cancer
Jonsson Comprehensive Cancer Center
Metastatic Prostate Adenocarcinoma · Prostate Adenocarcinoma With Focal Neuroendocrine Differentiation · Recurrent Prostate Carcinoma · Stage IVB Prostate Cancer AJCC v8
To Compare the Safety and Pharmacokinetics of PT105 With PT105R in Healthy Postmenopausal Female Volunteers
Peptron, Inc.
Prostate Cancer
Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGW
Johns Hopkins University
HIV · Prophylaxis · Transgender
Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE Study
ECOG-ACRIN Cancer Research Group
Prostate Carcinoma
Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial
NRG Oncology
Prostate Adenocarcinoma · Stage III Prostate Cancer AJCC v8 · Stage IVA Prostate Cancer AJCC v8
Phase II Study of the Use of Neoadjuvant Cabazitaxel With Hormonal Treatment in Patients Operable Prostate Cancer, Assess the Efficacy and Toxicity of Cabazitaxel, and Explore Potential Predictive and Prognostic Markers of Clinical Outcome
The Clatterbridge Cancer Centre NHS Foundation Trust
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer
Dana-Farber Cancer Institute
HER2-positive Breast Cancer · Invasive Carcinoma of the Breast · Breast Cancer · Node Negative Breast Cancer
PREOPERATIVE GONADOTROPINE-RELEASING HORMONE AGONIST THERAPY BEFORE SURGERY FOR UTERİN FIBROIDS
Alkü Alanya Education and Research Hospital
Uterine Fibroid · Gonadotropin-Releasing Hormone-Dependent Precocious Puberty
Apalutamide Plus Intermittent Hormone Therapy Versus Intermittent Hormone Therapy Alone in Prostate Cancer
The University of Texas Health Science Center, Houston
Prostate Cancer
The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's
Weill Medical College of Cornell University
Alzheimer Disease · Mild Cognitive Impairment
Androgen Deprivation Therapy and Apalutamide With or Without Radiation Therapy for the Treatment of Biochemically Recurrent Prostate Cancer, RESTART Study
M.D. Anderson Cancer Center
Biochemically Recurrent Prostate Carcinoma · Metastatic Prostate Carcinoma · Oligometastatic Prostate Carcinoma · Stage IV Prostate Cancer AJCC v8
Bariatric Arterial Embolization for Men Starting Hormones for Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Adenocarcinoma · Obesity, Morbid
A Multi-Center Trial of Androgen Suppression With Abiraterone Acetate, Leuprolide, PARP Inhibition and Stereotactic Body Radiotherapy in Prostate Cancer
University of Michigan Rogel Cancer Center
Prostate Cancer
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
ECOG-ACRIN Cancer Research Group
Biochemically Recurrent Prostate Carcinoma · Metastatic Prostate Carcinoma · Prostate Adenocarcinoma · Stage IVB Prostate Cancer AJCC v8
Neoadjuvant Study Chemotherapy vs Letrozole + Abemaciclib in HR+/HER2- High/Intermediate Risk Breast Cancer Patients
Spanish Breast Cancer Research Group
Early Breast Cancer
Skeletal Health and Bone Marrow Composition Among Youth
Amy DiVasta, MD
Gender Dysphoria in Children · Puberty · Bone Development
Comparison Elagolix vs Depot Leuprolide Prior to Frozen Embryo Transfers in Patients With Endometriosis
Colorado Center for Reproductive Medicine
Infertility · Endometriosis
Modified Downregulation for Women With Adenomyosis of the Uterus Prior to Frozen-thawed Embryo Transfer.
University College, London
Adenomyosis
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Neoadjuvant Tucidinostat and Exemestane in Early Breast Cancer
First Affiliated Hospital, Sun Yat-Sen University
Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Nivolumab + Docetaxel + ADT in mHSPC Patients With DDRD or Inflamed Tumors
Xiao X. Wei, MD
Hormone Sensitive Prostate Cancer · Prostate Adenocarcinoma · Metastasis Prostate Adenocarcinoma
Androgen Deprivation Therapy for Oligo-recurrent Prostate Cancer in Addition to radioTherapy
University Medical Center Groningen
Prostate Cancer
Real-life Study of Patients After 3-months of Leuprorelin 5mg Implant in Prostate Cancer
RECORDATI GROUP
Prostate Cancer
Neurobiology of Bulimia Nervosa
University of North Carolina, Chapel Hill
Bulimia Nervosa
Androgen Deprivation Therapy on Bone Mineral Density Change in Prostate Cancer Patients
Wonju Severance Christian Hospital
Prostatic Neoplasms
Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model
University of North Carolina, Chapel Hill
Perinatal Depression · Post Partum Depression · Depression, Postpartum · Depression
Comparison Between Two Different Protocols in Polycystic Ovary Symdrome Women Undergoing Intra-cytoplasmic Injection
Assiut University
Polycystic Ovary Syndrome
PersonaLized neoAdjuvant Strategy ER Positive and HER2 Negative Breast Cancer TO Increase BCS Rate
Seoul National University Hospital
Breast Cancer
Prediction of the PRONOUNCE Prostate Cancer Trial in Healthcare Claims Data
Brigham and Women's Hospital
Prostate Cancer
Postop Hypofractionated Radiation Therapy and LHRH in Patients With Prostate Cancer
McGill University Health Centre/Research Institute of the McGill University Health Centre
Prostate Cancer
Clinical Trial of Rapid Progressive Central Precocious Puberty With Integrative Chinese and Western Medicine
Children's Hospital of Fudan University
Idiopathic Precocious Puberty
A study of lidocaine jelly for pain relief in women receiving gonadotropin-releasing hormone analog injection during breast cancer treatment
Changhua Christian Hospital
Premenopausal women with hormone receptor-positive breast cancer
Neoadjuvant Hormonal Therapy Plus Palbociclib in Operable, Hormone Sensitive and HER2-Negative Primary Breast Cancer
Kyoto Breast Cancer Research Network
Breast Cancer Female · Hormone Receptor Positive Malignant Neoplasm of Breast
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Registry Study to Observe Clinical Outcomes of Participants With High-risk Metastatic Hormone-naïve Prostate Cancer in Japan
Janssen Pharmaceutical K.K.
Prostatic Neoplasms
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Defining Recurrent Disease With Axumin™
Cancer Center of Irvine
Prostate Cancer · Prostate Adenocarcinoma
REGN2810 Followed by Chemoimmunotherapy for Newly Metastatic Hormone-sensitive Prostate Cancer
Mark Stein
Prostate Cancer Metastatic
Clinical Study to Evaluate Efficacy and Safety of TAK-385 40 mg Compared With Leuprorelin in Patients With Endometriosis
ASKA Pharmaceutical Co., Ltd.
Endometriosis
A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery
RTOG Foundation, Inc.
Prostate Cancer
GnRH Agonist at Embryo Transfer: IVF Outcomes
Maimonides Medical Center
Infertility · Infertility, Female · Infertility, Male
Radiotherapy Combined With a LHRH (Ant)Agonist Versus Apalutamide in Patients With Biochemical Recurrence After RP
Cancer Research Antwerp
Cancer of Prostate
Understanding the Roles of Hormones in Adipocyte Remodeling Following Menopause
Pennington Biomedical Research Center
Menopause Surgical · Estrogen Deficiency · Adiposity · Follicle-Stimulating Hormone Deficiency
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Prostate Boost Irradiation With Stereotactic Body RT (SBRT)
Juravinski Cancer Center
Prostate Cancer
FACILE: FeAsibility of First-line RiboCIclib in OLdEr Patients with Advanced Breast Cancer
Fondazione Sandro Pitigliani
Breast Cancer
Neoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Study to Evaluate Leuprolide Acetate 45 mg 6-Month Formulation in Children With Central Precocious Puberty (CPP)
AbbVie
Central Precocious Puberty (CPP)
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
SWOG Cancer Research Network
Castration Levels of Testosterone · Metastatic Prostatic Adenocarcinoma · Stage IV Prostate Cancer AJCC v8 · Stage IVA Prostate Cancer AJCC v8
Comparative Study Between ICSI Results in Transvaginal Ultrasound Guided Embryo Transfer and Transabdominal Ultrasound Guided Embryo Transfer
Cairo University
Invitro Fertilization
Radium Ra 223 Dichloride, Hormone Therapy and Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Prostate Cancer
City of Hope Medical Center
Prostate Adenocarcinoma
A Pilot Study of 5-AZA and ATRA for Prostate Cancer With PSA-only Recurrence After Local Treatment
Icahn School of Medicine at Mount Sinai
Prostatic Neoplasms · Prostate Neoplasms · Prostate Cancer
A Study to Evaluate Exemestane Tablets Combined With Ovarian Function Suppression/Ablation in Treatment of Premenopausal Breast Cancer Patients With CYP2D6*10 Mutations （STEP）
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
CYP2D6 Polymorphism
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies, Radiotherapy, & Surgery
The Methodist Hospital Research Institute
High-risk Prostate Cancer · Prostate Cancer
Role of Suppression of Endometriosis With Progestins Before IVF-ET
National Research Centre, Egypt
IVF · Endometriosis · Pregnancy Rate · Progestins
Comparison of a Novel Leuprolide With Market Leuprolide
Lee's Pharmaceutical Limited
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Systemic and Tumor-Directed Therapy for Oligometastatic Prostate Cancer
VA Office of Research and Development
Newly Diagnosed Oligometastatic Prostate Cancer
Effect of Short Term Ovarian Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess
University of Virginia
Hyperandrogenemia · Obesity · Polycystic Ovary Syndrome
Treatment of Uterine Fibroids With Magnetic Resonance Guided High Intensity Focused Ultrasound
Thunder Bay Regional Health Research Institute
Uterine Leiomyoma
The Influence of Gonadal Hormone Suppression on Adipocyte Lineage and the Microbiome
University of Colorado, Denver
Adipose Tissue · Microbiome · Menopause
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Aromatase Plus GnRH Analogue Versus GnRH Analog Alone in Adenomyosis
Centre for Endocrinology and Reproductive Medicine, Italy
Uterine Adenomyosis · Recurrent Implantation Failure · Menstrual Pain
Study to Evaluate the Safety and Efficacy of Switching From Zoladex® Monthly or Quarterly, to Eligard® Semiannual.
Zodiac Produtos Farmaceuticos S.A.
Prostate Cancer
Specified Drug-Use Survey of Leuprorelin Acetate Injection Kit 11.25 mg "All-Case Investigation: Spinal and Bulbar Muscular Atrophy (SBMA)"
Takeda
Spinal and Bulbar Muscular Atrophy
Study to Compare Neoadjuvant Combination of Trastuzumab and Pertuzumab With Concurrent Taxane Chemotherapy or Endocrine Therapy and Quality of Life Assessment Under Adjuvant Therapy in Operable HER2+/HR+ Breast Cancer Patients
Palleos Healthcare GmbH
Breast Neoplasms
Safety, Efficacy, and Pharmacokinetic Behavior of Leuprolide Mesylate (LMIS 25 mg) in Subjects With Prostate Cancer
Foresee Pharmaceuticals Co., Ltd.
Prostatic Neoplasms
Pembrolizumab and Exemestane/ Leuprolide in Premenopausal HR+/ HER2- Locally Advanced or Metastatic Breast Cancer
National Taiwan University Hospital
Premenopausal Breast Cancer
Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant or Letrozole, Based on Prior Endocrine Therapy, in Patients With PIK3CA Mutant, HR+, HER2- Advanced Breast Cancer Who Have Progressed on or After Prior Treatments
Novartis Pharmaceuticals
Breast Cancer
A Study of Pharmacokinetic/Pharmacodynamic Profile of Orally Administered Leuprolide in Healthy Female Volunteers
Enteris BioPharma Inc.
Endometriosis
Value of Cabergoline and Low Dose Aspirin in Poor Responders Undergoing ICSI-ET With GnRH Agonist Flare-Up-Protocol
Cairo University
Invitro Fertilization
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Menopausal Sleep Fragmentation and Body Fat Gain
Brigham and Women's Hospital
Menopause
A Study to Assess the Safety and Efficacy of Enantone (Leuprorelin) in Central Precocious Puberty (CPP) Among Chinese Participants
Takeda
Central Precocious Puberty
A Study of ELIGARD® in Hormone-dependent Prostate Cancer Patients
Astellas Pharma Singapore Pte. Ltd.
Prostate Cancer
A Study of Docetaxel + ARN-509 in Castration-Resistant Prostate Cancer
Dana-Farber Cancer Institute
Prostate Cancer
Pembrolizumab +/- SD-101 in Hormone-Naïve Oligometastatic Prostate Cancer With RT and iADT
David Oh
Prostatic Neoplasms
Neo-adjuvant Chemotherapy With Letrozole in Patients With Estrogen Receptor Positive/HER-2 Negative Breast Cancer
National Cancer Center, Korea
Breast Cancer · Invasive Breast Cancer
The Relation of GnRH Treatment to QTc Interval in Transgender Females
University of California, San Francisco
Gender Dysphoria
A Study to Evaluate the Safety and Efficacy of Relugolix in Men With Advanced Prostate Cancer
Myovant Sciences GmbH
Prostate Cancer
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery
NRG Oncology
Stage I Prostate Adenocarcinoma AJCC v7 · Stage II Prostate Adenocarcinoma AJCC v7 · Stage III Prostate Adenocarcinoma AJCC v7
Brown Adipose Tissue Activity in Pre- and Postmenopausal Women
University of Colorado, Denver
Menopause · Obesity
A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer
Alliance Foundation Trials, LLC.
Prostate Cancer
A Study of Definitive Therapy to Treat Prostate Cancer After Prostatectomy
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Cancer
Phase 1 Study to Evaluate the Pharmacokinetics and Safety Following SC Administration of DWJ108J in Patients With Prostate Cancer
Daewoong Pharmaceutical Co. LTD.
Prostate Cancer
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study
Astellas Pharma Global Development, Inc.
Prostate Cancer
Study to Assess the Safety and Efficacy of Ribociclib (LEE011) in Combination With Letrozole for the Treatment of Men and Pre/Postmenopausal Women With HR+ HER2- aBC
Novartis Pharmaceuticals
Breast Cancer
Generation of Positive Biological Samples to Leuprolide Acetate for Doping Control
Parc de Salut Mar
There Are no Conditions Under Study. Healthy Volunteers
Triggering of Follicular Maturation
Assiut University
Increase Pregnancy Rate
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Neoadjuvant And Adjuvant Abiraterone Acetate + Apalutamide Prostate Cancer Undergoing Prostatectomy
Dana-Farber Cancer Institute
Prostate Cancer
Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer
Case Comprehensive Cancer Center
Prostate Cancer
Management of Castration-Resistant Prostate Cancer with Oligometastases
Sir Mortimer B. Davis - Jewish General Hospital
Castration-resistant Prostate Cancer Patients with Oligometastases
Anti-Androgens and Cabazitaxel in Defining Complete Response in Prostatectomy (ACDC Trial)
University Health Network, Toronto
Prostate Cancer
Fertility-sparing Therapy for Patients With Stage IA Endometrial Cancer
Peking University People's Hospital
Endometrial Neoplasms · Endometrial Neoplasm Malignant · Endometrial Neoplasm Malignant Stage I · Carcinoma, Endometrioid
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Analysis of Body Mass Index in Central Precocious Puberty Patients Treated With Leuprolide Acetate
Kyungpook National University Hospital
Precocious Puberty, Central
A Study of Palbociclib With Exemestane Plus GnRH Versus Capecitabine in Premenopausal Women With HR+ MBC
Samsung Medical Center
Metastatic Breast Cancer
A Study of Definitive Therapy to Treat Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Cancer
Real-life Evaluation of the Effect of ADT in Prostate Cancer Patients in Asia (READT Asia Study)
Chinese University of Hong Kong
Prostate Cancer
AASUR in High Risk Prostate Cancer
Memorial Sloan Kettering Cancer Center
Prostate Cancer
Late Phase II Clinical Study of KLH-2109 in Patients With Endometriosis
Kissei Pharmaceutical Co., Ltd.
Endometriosis
A Trial Comparing Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Advanced Prostate Cancer and Cardiovascular Disease
Ferring Pharmaceuticals
Prostate Cancer
NEOADjuvant Aromatase Inhibitor and Pertuzumab/Trastuzumab for Women With Breast Cancer
Midwestern Regional Medical Center
Breast Neoplasms
Special Drug Use Surveillance of Leuplin PRO for Injection Kit 22.5 mg for "Prostate Cancer"
Takeda
Prostate Cancer
CKD-841 Pharmacokinetic/Pharmacodynamic Study
Chong Kun Dang Pharmaceutical
Postmenopausal Disorder
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Adjuvant Ovarian Suppression Plus Aromatase Inhibitor or Tamoxifen in Young Women
First Affiliated Hospital, Sun Yat-Sen University
Breast Cancer
Special Drug Use Surveillance of Leuprorelin for Injection Kit 22.5 mg in "Premenopausal Breast Cancer"
Takeda
Premenopausal Breast Cancer
A Phase 3 Study to Evaluate the Efficacy and Safety of Relugolix (TAK-385) 40 mg Compared With Leuprorelin in the Treatment of Uterine Fibroids
Takeda
Uterine Fibroids
Open-Label Safety Extension Study in Patients Who Have Previously Participated and Have Benefited From LMIS 50 mg
Foresee Pharmaceuticals Co., Ltd.
Prostatic Neoplasms
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Trial of Radiotherapy With Leuprolide and Enzalutamide in High Risk Prostate Cancer
University of California, San Francisco
Prostatic Neoplasms · Pelvic Nodal
56021927PCR3002
Janssen Cilag International
Metastatic Hormone-sensitive Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Enzalutamide Versus Standard Androgen Deprivation Therapy for the Treatment Hormone Sensitive Prostate Cancer
University of Colorado, Denver
Adenocarcinoma of the Prostate · Recurrent Prostate Cancer · Stage III Prostate Cancer · Stage IV Prostate Cancer
Efficacy and Safety of Medication Used to Stimulate Ovulation
Create Fertility Center
IVF Cycle · Ovarian Stimulation · Egg Retrieval · Pregnancy
Androgen Deprivation Therapy or Androgen Deprivation Therapy Plus Definitive Treatment (Radiation or Surgery)
Fudan University
Prostate Cancer
GnRH-a on Angiogenesis of Endometriosis
University of Patras
Angiogenesis · Endometriosis
Detect V / CHEVENDO (Chemo vs. Endo)
Prof. Wolfgang Janni
Metastatic Breast Cancer
Study of Leuprolide Acetate Injectable Suspension in the Treatment of Central Precocious Puberty
Tolmar Inc.
Precocious Puberty, Central
C3431004/MDV3100-13
Medivation Inc.
Prostate Cancer
A Study to Assess the Safety and Efficacy of Leuprorelin in Central Precocious Puberty in Chinese Participants
Takeda
Central Precocious Puberty
Endometrial Receptivity Profile in Patients With Endometrial Proliferation Defects
Reproductive Medicine Associates of New Jersey
Endometrial Dysfunction
PLX3397, Radiation Therapy, and Antihormone Therapy in Treating Patients With Intermediate- or High-Risk Prostate Cancer
Barbara Ann Karmanos Cancer Institute
Stage I Prostate Adenocarcinoma · Stage II Prostate Adenocarcinoma · Stage III Prostate Adenocarcinoma
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Impact of Radical Prostatectomy as Primary Treatment in Patients With Prostate Cancer With Limited Bone Metastases
Martini-Klinik am UKE GmbH
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
COmbining Oral Letrozole and Clomiphene for Ovarian Stimulation (COOL-COS) Associated With Corifollitropin Alfa: a Pilot Study
University of Sao Paulo
Infertility
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Micro RNAs to Predict Response to Androgen Deprivation Therapy
Medical College of Wisconsin
Prostate Cancer
Regulation of Cervical Mucus Secretion
Oregon Health and Science University
Fertility · Contraception
Cytoreductive Prostatectomy in Treating Patients With Newly Diagnosed, Metastatic Prostate Cancer
Rutgers, The State University of New Jersey
Metastatic Prostate Carcinoma · Metastatic Prostatic Adenocarcinoma · Prostate Carcinoma Metastatic to the Bone
Testosterone Regulation of the Natriuretic Peptide System
Massachusetts General Hospital
Hypertension
Ulipristal Acetate Versus GnRH Analogue Treatment Before Hysteroscopic Resection of Uterine Leiomyoma
University Magna Graecia
Fibroid
Ulipristal Acetate for the Preoperative Management of Hypoechoic Cellular Leiomyomas
University Magna Graecia
Fibroid
Ulipristal Acetate Versus GnRH Analogue and Myometrial Preservation
University Magna Graecia
Fibroid
High-Dose Brachytherapy in Treating Patients With Prostate Cancer
Stanford University
Prostate Adenocarcinoma · Stage I Prostate Cancer · Stage IIA Prostate Cancer · Stage IIB Prostate Cancer
GnRH Agonist and Progesterone Versus Progesterone Only for Luteal Phase Support in Antagonist Cycles
Queensland Fertility Group
Infertility
Assessment of Myeloid Cell Constitution in the Follicular Fluid of Women Undergoing In-vitro Fertilization
Hillel Yaffe Medical Center
Infertility
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Safety and Efficacy Study of Enzalutamide Plus Leuprolide in Patients With Nonmetastatic Prostate Cancer (EMBARK)
Pfizer
Hormone Sensitive Prostate Cancer · Prostate Cancer · Cancer of the Prostate
Fairly Brief Androgen Suppression and Stereotactic Radiotherapy for High Risk Prostate Cancer - Protocol 2
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Bay98-7196, Dose Finding / POC Study
Bayer
Endometriosis
Enzalutamide/Leuprolide +/- Abiraterone/Pred in Prostate
Dana-Farber Cancer Institute
Prostate Adenocarcinoma · Prostate Cancer · High Risk Prostate Cancer
Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
University of Colorado, Denver
Cognitive Impairment · Executive Dysfunction · Endothelial Dysfunction · Cardiovascular Disease
Phase II Study of Subcutaneous Injection Depot of Leuprolide Acetate in Patient With Prostate Cancer
Camurus AB
Prostate Cancer
Salvage Radiotherapy Combined With Hormonotherapy in Oligometastatic Pelvic Node Relapses of Prostate Cancer
Institut Cancerologie de l'Ouest
Prostate Cancer
A Study in Patients With Metastatic Prostate Cancer to Assess How the Drug Eligard®, Affects Certain Markers in Blood and Urine, Which Are Indicators for the Disease
Astellas Pharma Europe Ltd.
Metastatic Prostate Cancer
Safety, Efficacy, and Pharmacokinetic Behavior of Leuprolide Mesylate in Subjects With Advanced Prostate Carcinoma
Foresee Pharmaceuticals Co., Ltd.
Prostatic Neoplasms
Supportive Therapy in Androgen Deprivation Clinic in Improving Health Outcomes and Managing Side Effects in Patients With Prostate Cancer
University of California, San Francisco
Prostate Adenocarcinoma
A Phase II Study of Androgen Deprivation Therapy With or Without Palbociclib in RB-Positive Metastatic Prostate Cancer
University of Michigan Rogel Cancer Center
Prostate Cancer
Study of the Effect of Testosterone and Estradiol on NP Responses to Acute and Chronic Salt Loading
Massachusetts General Hospital
Hypertension
Enzalutamide and Hormone Therapy Before, During, and After Radiation for High Risk Localized Prostate Cancer
University of Texas Southwestern Medical Center
Prostate Cancer
LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Hormone Sensitive Prostate Cancer
Barbara Ann Karmanos Cancer Institute
Adenocarcinoma of the Prostate · Recurrent Prostate Cancer · Stage IV Prostate Cancer
Enzalutamide, Radiation Therapy and Hormone Therapy in Treating Patients With Intermediate or High-Risk Prostate Cancer
Thomas Jefferson University
Adenocarcinoma of the Prostate · Recurrent Prostate Cancer · Stage IIB Prostate Cancer · Stage III Prostate Cancer
Salvage Therapeutic Radiation With Enzalutamide and ADT in Men With Recurrent Prostate Cancer (STREAM)
Duke University
Prostate Cancer
The Effect of GnRH Agonist Administered in the Luteal Phase on ART Cycle Outcomes
Zekai Tahir Burak Women's Health Research and Education Hospital
Infertility
Efficacy of Recombinant FSH/GnRH Antagonist Protocol With and Without LH Adjunct for Egg Bank Donation
Michigan Reproductive Medicine
Egg Donation
A Phase 2 Study to Evaluate the Safety and Efficacy of TAK-385, Together With a Leuprorelin Observational Cohort, in Participants With Prostate Cancer
Millennium Pharmaceuticals, Inc.
Prostate Cancer
Abiraterone, Radiotherapy and Short-Term Androgen Deprivation in Unfavorable Localized Prostate Cancer
Duke University
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Study of GnRH-A [Leuprorelin(Lorelin Depot] Plus Leterozole +/- Everolimus for Premenopausal Women With Metastatic Breast Cancer
Asan Medical Center
Metastatic Breast Cancer
Bevacizumab Plus Paclitaxel Optimization Study With Interventional Aintenance Endocrine Therapy in Breast Cancer
Japan Breast Cancer Research Group
Metastatic Breast Cancer
S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer
SWOG Cancer Research Network
Breast Cancer
An Observational Study Looking at How Well the Drug Eligard Works and How Well it is Tolerated by the Body of Patients With Advanced Prostate Carcinoma in the Russian Federation
Astellas Pharma Europe B.V.
Advanced Prostate Carcinoma
Weekly Paclitaxel and Cisplatin to Treat Hormone Receptor Positive and Triple Negative Breast Cancer Patients
RenJi Hospital
Tubular Breast Cancer · Mucinous Breast Cancer · Invasive Ductal Breast Cancer · Inflammatory Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition
University of North Carolina, Chapel Hill
Postpartum Depression
Stereotactic Boost and Long-Term Androgen Deprivation for Adenocarcinoma of the Prostate
University of California, Davis
Adenocarcinoma of the Prostate
A Study of the Effect of Enantone LP 11.25 mg (Leuprorelin) on the Histological Progression of Indolent Prostate Cancer
Takeda
Prostate Cancer
Neoadjuvant Chemo-endocrine Therapy Versus Chemotherapy Alone in ER-positive, HER2-negative Breast Cancer
Fudan University
Breast Cancer Female
Effects of Estrogen Deficiency on Energy Expenditure
University of Colorado, Denver
Obesity
S1216, Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer
SWOG Cancer Research Network
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
The Role of Highly Selective Androgen Receptor (AR) Targeted Therapy in Men With Biochemically Relapsed Hormone Sensitive Prostate Cancer
Aragon Pharmaceuticals, Inc.
Prostate Cancer
A Study of Neoadjuvant TAK-700 and Leuprorelin Acetate Followed by Surgery Versus Surgery Alone
Centre of Experimental Medicine
Prostate Cancer
Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer
M.D. Anderson Cancer Center
Prostate Adenocarcinoma · Recurrent Prostate Carcinoma
Bipolar Androgen-based Therapy for Prostate Cancer (BAT)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Recurrent Prostate Cancer
Study of Dual Trigger Ovulation in Oocyte Donors
Weill Medical College of Cornell University
Infertility
Anastrazole Plus GnRH-agonist in the Treatment of Endometriosis Recurrence
Centre for Endocrinology and Reproductive Medicine, Italy
Endometriosis
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
A Study to Assess the Effectiveness and Safety of Different Doses of ASP1707 Compared to Placebo for Endometriosis Associated Pelvic Pain
Astellas Pharma Europe B.V.
Endometriosis
Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation
Memorial Sloan Kettering Cancer Center
Leukemia · Multiple Myeloma · Myelodysplastic Syndrome · Non-Hodgkin's Lymphoma
Degarelix in the Treatment of Endometriosis Recurrence
Centre for Endocrinology and Reproductive Medicine, Italy
Endometriosis
Study of Everolimus Added to Combined Hormonal and Radiation Therapy for High Risk Prostate Cancer
University of Michigan Rogel Cancer Center
Prostate Cancer
Females, Aging, Metabolism, and Exercise
University of Colorado, Denver
Obesity
Study of Comprehensive Diagnosis and Treatment for Children Precocious Puberty
Ruijin Hospital
Central Precocious Puberty
Postoperative Radiation Therapy, Hormonal Therapy and Concurrent Docetaxel for High Risk Pathologic Prostate Cancer
University of Kansas Medical Center
Prostate Cancer
Tamoxifen +/- GnRH Analogue vs Aromatase Inhibitor + GnRH Analogue in Male Breast Cancer Patients
GBG Forschungs GmbH
Male Breast Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) With Leuprolide + Letrozole and (3) Everolimus + EDT in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLL-HCC)
Memorial Sloan Kettering Cancer Center
Fibrolamellar Carcinoma · Fibrolamellar Liver Cancer
External Beam Radiation With or Without Chemotherapy to Treat High Risk Prostate Cancer
Proton Collaborative Group
Prostate Cancer
Effect of GnRH Antagonist vs Agonist Long on IVF Outcome, Peak Estradiol Level,and Duration of Stimulation
Main Line Fertility Center
Fertility
Neoadjuvant Chemohormonal Therapy Followed by Salvage Surgery for High Risk PSA
H. Lee Moffitt Cancer Center and Research Institute
Prostate Cancer
Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer
Radiation Therapy Oncology Group
Prostate Cancer
Gene Expression Profile After Gonadotropin Releasing Hormone (GnRH) Agonist Trigger of Oocyte Maturation
UConn Health
Endometrial Receptivity · Ovarian Hyperstimulation Syndrome
Study on Influence of Leutinizing Hormone (LH) on Oocyte Maturity
Southern Cross Fertility Centre
Infertility
Study of Enzalutamide (Formerly MDV3100) as a Neoadjuvant Therapy for Patients Undergoing Prostatectomy for Localized Prostate Cancer
Pfizer
Prostate Cancer
A Long-term Extension Study of TAK-385 in the Treatment of Endometriosis
Takeda
Endometriosis
Phase II Study of DCVAC/PCa Added to Hormone Therapy for Men With Metastatic Prostate Cancer
SOTIO a.s.
Prostate Cancer
Obesity as a Risk Factor for Musculoskeletal Diseases in the U.S. Air Force: Associations and Implications for Force Readiness
Mike O'Callaghan Military Hospital
Obesity
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Relationship Between the Menstrual Cycle and Heart Disease in Women
Oregon Health and Science University
Coronary Heart Disease
Examination of Serum Progesterone Levels in an IVF Population Following Two Types of Egg Aspiration
Red Rock Fertility Center
Infertility, Female
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Observational, Non-interventional, Non Comparative Real Life Data Collection of Depo-Eligard® 7.5 mg, 22.5 mg and 45 mg in Male Prostate Cancer Patients
Astellas Pharma Europe B.V.
Prostate Cancer
Efficacy and Safety of TAK-385 in the Treatment of Endometriosis
Takeda
Endometriosis
Efficacy and Safety of Leuprolide Acetate 22.5 mg Depot in Treatment of Prostate Cancer
GP-Pharm
Prostate Cancer
Sequencing of Sipuleucel-T and ADT in Men With Non-metastatic Prostate Cancer
Dendreon
Prostatic Neoplasm · Prostate Cancer · Prostatic Adenocarcinoma
Leuplin SR 11.25 mg Injection Kit Specified Drug-use Survey: "QOL Survey in Premenopausal Breast Cancer Patients"
Takeda
Breast Cancer
UC-0160/1003
Unicancer
Prostatic adenocarnicoma with high risk of recurrence
The Clinical Trial to Evaluate the Efficacy and Safety of Luphere Depot Inj. 3.75mg(Leuprolide Acetate 3.75mg) in Patients With Precocious Puberty
Daewoong Pharmaceutical Co. LTD.
Central Precocious Puberty
Evaluation of Adjuvant Hormonal Treatment for 24 Months After Radical Prostatectomy in High Risk of Recurrence Patients.
UNICANCER
Metastases
Preservation of Ovarian Function After Hematopoietic Cell Transplant
Masonic Cancer Center, University of Minnesota
Multiple Myeloma · Non-Hodgkin Lymphoma · Hodgkin Disease · Acute Myeloid Leukemia
Real Life Evaluation of Lupron in the Management of Prostate Cancer: A Canadian Post Marketing Observational Study
AbbVie (prior sponsor, Abbott)
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Ipilimumab + Androgen Depravation Therapy in Prostate Cancer
M.D. Anderson Cancer Center
Prostate Cancer
Effect of GTx-758 on Total and Free Testosterone Levels in Men With Prostate Cancer
GTx
Prostate Cancer
GnRH-a for Ovarian Protection During CYC Therapy for Rheumatic Diseases
Joseph Mccune
Lupus Erythematosus, Systemic · Systemic Vasculitis · Isolated Angiitis of Central Nervous System · Lung Disease With Systemic Sclerosis
Pilot Study of Leuprolide to Improve Immune Function After Allogeneic Bone Marrow Transplantation
National Cancer Institute (NCI)
Myelodysplastic Syndrome · Acute Lymphocytic Leukemia · Acute Myelogenous Leukemia · Chronic Myelogenous Leukemia
Initiation of Androgen Deprivation Therapy for Prostate Cancer Using Degarelix Followed by Leuprolide
Urology of Virginia
Prostate Cancer
Trial of Hypofractionated IMRT Boost Versus Conventional IMRT Boost for Localized High Risk Prostate Cancer
Sunnybrook Health Sciences Centre
Prostate Cancer
Observational Program to Assess Routine Use of Add-back Therapy in Patients With Endometriosis in Russian Federation, Planned for 6-month Course of Lucrin Depot® (Leuprorelin)
AbbVie (prior sponsor, Abbott)
Genital Endometriosis
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Efficacy and Safety Study of ELIGARD 22.5mg With Prostate Cancer
HanAll BioPharma Co., Ltd.
Prostate Cancer
Maximal Stimulation and Delayed Fertilization for Diminished Ovarian Reserve: a Randomized Pilot Study
Wake Forest University Health Sciences
Infertility
Bicalutamide and Goserelin or Leuprolide Acetate With or Without Cixutumumab in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer
National Cancer Institute (NCI)
Prostate Adenocarcinoma · Recurrent Prostate Carcinoma · Stage IV Prostate Cancer
Study in Men With Prostate Cancer to Assess the Safety, Pharmacokinetics and Testosterone-Lowering Efficacy of TAK-448
Millennium Pharmaceuticals, Inc.
Prostate Cancer · Prostatic Neoplasms
Neoadjuvant Ipilimumab in Prostate Cancer
M.D. Anderson Cancer Center
Prostate Cancer
Pharmacodynamics of Lorelin Depot (Leuprorelin Acetate - Bergamo) Compared to Lupron Depot ® (Leuprorelin Acetate - Abbot)
Azidus Brasil
Healthy
Leuprolide Acetate or Goserelin Acetate With or Without Vismodegib Followed by Surgery in Treating Patients With Locally Advanced Prostate Cancer
National Cancer Institute (NCI)
Prostate Adenocarcinoma · Stage IIA Prostate Cancer AJCC v7 · Stage IIB Prostate Cancer AJCC v7
Randomized Crossover Trial to Assess the Tolerability of Gonadotropin Releasing Hormone (GnRH) Analogue Administration
Watson Pharmaceuticals
Prostate Cancer
Influence of Male Hormones on Regional Fat Metabolism
Mayo Clinic
Obesity
Abiraterone Prednisone and Hormonal Therapy Before and During Radiation Therapy in Localized Prostate Cancer
University of Washington
Adenocarcinoma of the Prostate · Stage II Prostate Cancer · Stage III Prostate Cancer · Stage IV Prostate Cancer
Levonorgestrel-releasing Intrauterine System in Patients With Endometriosis
University of Sao Paulo
Endometriosis
Neo-adjuvant Abiraterone + Luteinizing Hormone-Releasing Hormone (LHRH) Versus LHRH in Prostate Cancer
Cougar Biotechnology, Inc.
Prostate Cancer
Impact of Hot Flashes on Sleep and Mood Disturbance
Massachusetts General Hospital
Menopause · Depression · Hot Flashes
A Phase 2 Study to Evaluate Safety and Efficacy of Abiraterone Acetate in Male Participants With Prostate Cancer
Janssen Research & Development, LLC
Prostate Cancer
Post-operative or Early Salvage XRT and ADT for High Risk PCa
European Organisation for Research and Treatment of Cancer - EORTC
Prostate Cancer
Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer
Radiation Therapy Oncology Group
Prostate Cancer
Leuprolide Acetate or Goserelin Acetate Compared With Observation in Treating Patients With High-Risk Prostate Cancer Who Have Undergone Radical Prostatectomy
Mayo Clinic
Prostate Adenocarcinoma · Stage IIA Prostate Cancer · Stage IIB Prostate Cancer · Stage III Prostate Cancer
R-(-)-Gossypol and Androgen Ablation Therapy in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer
National Cancer Institute (NCI)
Adenocarcinoma of the Prostate · Stage IV Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Extended Endocrine Therapy for Premenopausal Women With Breast Cancer
Dana-Farber Cancer Institute
Breast Cancer
A Study of Degarelix in Patients With Prostate Cancer
Ferring Pharmaceuticals
Prostate Cancer
Polycystic Ovary Syndrome (PCOS) and In Vitro Fertilization (IVF): A Comparison Between Standard Long Protocol Versus an Antagonist Protocol Starting on Day 1
Fundacion Dexeus
Polycystic Ovary Syndrome · In Vitro Fertilization
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Neoadjuvant Dasatinib Plus LHRH Analogue Therapy in High-Risk Localized Prostate Cancer
Noah Hahn, M.D.
Prostate Cancer
Everolimus, Bicalutamide, and Leuprolide Acetate in Treating Patients Undergoing Radiation Therapy For High-Risk Locally Advanced Prostate Cancer
Institut du Cancer de Montpellier - Val d'Aurelle
Prostate Cancer
Oral Microdose Lupron Versus Luteal Estradiol Trial in Poor Responder In Vitro Fertilization (IVF) Patients
Weill Medical College of Cornell University
Infertility
Menopur® Versus Follistim® in Polycystic Ovarian Syndrome (PCOS)
Ferring Pharmaceuticals
Polycystic Ovarian Syndrome · Infertility
Safety Extension Study Of Leuprolide Acetate (Lupron Depot) In The Treatment Of Central Precocious Puberty
AbbVie (prior sponsor, Abbott)
Precocious · Leuprolide Acetate · Luteinizing Hormone (LH) · Gonadotrophin-releasing Hormone Agonist (GnRHa)
Efficacy and Safety Study of Elagolix Versus Placebo or Leuprorelin Acetate in Endometriosis
AbbVie
Endometriosis
Androgen Deprivation Therapy +/- Bevacizumab for PSA Recurrence of Prostate Cancer After Definitive Local Therapy
Dana-Farber Cancer Institute
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Lucrin® Depot Efficacy and Safety Monitoring Study in Patients With Advanced Prostate Cancer and Lower Urinary Tract Symptoms (LUTS)
Abbott
Advanced Prostate Cancer · Lower Urinary Tract Symptoms
Safety Study of Sorafenib With Androgen Deprivation and Radiotherapy to Treat Prostate Cancer
Beth Israel Medical Center
Prostate Cancer
Retrospective, Non-interventional Study of Depo-Eligard®.
Astellas Pharma Inc
Prostate Cancer
Does Letrozole Improve the Outcomes and/or Reduce the Cost of IVF-ET Cycles?
Center for Human Reproduction
Infertility
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
PGL4001 Versus GnRH-agonist in Uterine Myomas
PregLem SA
Uterine Myomas
Androgen Ablation Therapy With or Without Vaccine Therapy in Treating Patients With Prostate Cancer
Eastern Cooperative Oncology Group
Prostate Cancer
Androgen Suppression and Radiation With/Out Docetaxel in High-Risk Localized Prostate Cancer
NCIC Clinical Trials Group
Prostate Cancer
A Study of Leuprolide 11.25 mg and 30 mg Administered Every 3 Months to Treat Central Precocious Puberty
Abbott
Puberty, Precocious
Prevention of Obesity in Women Via Estradiol Regulation
University of Colorado, Denver
Obesity
Efficacy and Safety Study of a New Leuprolide Acetate 17 mg Depot to Treat Prostate Cancer Patients
GP-Pharm
Prostate Cancer
Pharmacokinetics, Safety and Efficacy Study of Proellex in Pre-menopausal Women With Symptomatic Uterine Fibroids
Repros Therapeutics Inc.
Uterine Fibroids
Luteinizing Hormone-Releasing Hormone Agonist Therapy and Iodine I 125 Implant in Treating Patients With Previously Untreated Prostate Cancer
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer
Radiation Therapy Oncology Group
Prostate Cancer
A Study of Leuprolide to Treat Prostate Cancer
Abbott
Prostate Cancer
Sunitinib Malate, Hormone Ablation and Radiation Therapy in Patients With Prostate Cancer
M.D. Anderson Cancer Center
Prostate Cancer
Embryo Aneuploidies and Ovarian Stimulation
Instituto Valenciano de Infertilidad, IVI VALENCIA
Embryo Aneuploidies
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Aromatase inhibitors in girls: Anastrozole combined to the LHRH analogue leuprorelin in Girls with early or precocious puberty and a compromised growth potential
Attikon University Hospital
Compromised predicted adult height in girls with early or precocious puberty
Comparison of Two Pharmacological Treatments of Pedophilia
Institut National de la Santé Et de la Recherche Médicale, France
Pedophilia
Metabolic Study of Women With Polycystic Ovary Syndrome and Sleep Apnea
University of Chicago
Polycystic Ovary Syndrome · Obstructive Sleep Apnea
Androgen Deprivation Therapy and Vorinostat Followed by Radical Prostatectomy in Treating Patients With Localized Prostate Cancer
National Cancer Institute (NCI)
Prostate Adenocarcinoma · Stage I Prostate Cancer · Stage IIA Prostate Cancer · Stage IIB Prostate Cancer
RADICALS - Radiotherapy and Androgen Deprivation In Combination After Local Surgery
University College, London
Gastrointestinal Complications · Prostate Cancer · Sexual Dysfunction · Urinary Complications
Hormone Therapy and Temsirolimus in Treating Patients With Relapsed Prostate Cancer
National Cancer Institute (NCI)
Adenocarcinoma of the Prostate · Recurrent Prostate Cancer
Study of Abraxane Plus Hormonal Therapy as Initial Treatment of Unresectable or Metastatic Prostate Cancer
The Methodist Hospital Research Institute
Prostatic Neoplasms
A Study of Androgen Deprivation With Leuprolide, +/- Docetaxel for Clinically Asymptomatic Prostate Cancer Participants With a Rising Prostate Specific Antigen (PSA)
Sanofi
Prostatic Neoplasms
Surgery With or Without Docetaxel and Leuprolide or Goserelin in Treating Patients With High-Risk Localized Prostate Cancer
Alliance for Clinical Trials in Oncology
Prostate Cancer
The ELDORADO (Eligard®, Docetaxel and Radiotherapy) Study
Nova Scotia Cancer Centre
Prostatic Neoplasms
Safety and Efficacy Study of Leuprolide Acetate for Injectable Suspension 22.5 MG in the Treatment of Prostate Cancer
Oakwood Laboratories, LLC
Prostate Cancer
A Long-term Extension Study Evaluating a One-Month Dosing Regimen of Degarelix in Prostate Cancer Requiring Androgen Ablation Therapy
Ferring Pharmaceuticals
Prostate Cancer
Letrozole and Goserelin or Leuprolide in Treating Premenopausal Estrogen Receptor-Positive Patients With Stage IV Breast Cancer
University of Washington
Breast Cancer
Docetaxel, Radiation Therapy, and Hormone Therapy in Treating Patients With Locally Advanced Prostate Cancer
Medical University of South Carolina
Prostate Cancer
PROtecting Ovaries and Fertility During Chemotherapy - The PROOF Trial
Ottawa Hospital Research Institute
Fertility Preservation · Cancer
Hormone Therapy and Intensity-Modulated Radiation Therapy in Treating Patients With Metastatic Prostate Cancer
City of Hope Medical Center
PSA Level Greater Than Two · Stage IV Prostate Adenocarcinoma AJCC v7
A Pharmacodynamic Study of Leuprorelin Gelatin-Free Formulation in Female Subjects With Uterine Fibroids.
Takeda
Uterine Fibroids
Somatropin + Leuprorelin vs Somatropin Alone in Pubertal Children With Idiopathic Short Stature
Eli Lilly and Company
Idiopathic Short Stature (ISS)
Pazopanib Hydrochloride After Leuprolide Acetate or Goserelin Acetate in Treating Patients With Relapsed Prostate Cancer
National Cancer Institute (NCI)
Recurrent Prostate Cancer
Sunitinib Malate With Hormonal Ablation for Patients Who Will Have Prostatectomy
M.D. Anderson Cancer Center
Prostate Cancer
Effect of Increased Circulating Androgens on Granulosa Cell Responses to FSH.
University of California, San Diego
Polycystic Ovary Syndrome
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Follicle-Stimulating Hormone (FSH) and the Onset of Puberty
University of Utah
Delayed Puberty · Precocious Puberty
A Phase IIIb Study of Intermittent Versus Continuous Hormone Deprivation Treatment With ELIGARD
Astellas Pharma Inc
Prostate Cancer
A Study to Evaluate the Ability of Lupron Depot to Enhance Immune Function Following Bone Marrow Transplantation
Abbott
Hodgkin Disease · Lymphoma, Non-Hodgkin · Multiple Myeloma · Mantle Cell Lymphoma
The Efficacy and Safety of Degarelix One Month Dosing Regimens in Prostate Cancer
Ferring Pharmaceuticals
Prostate Cancer
A Novel Approach to Endometrial Preparation in Recipients of Donor Eggs
Kelly, Maureen, M.D.
Implantation, Embryo
Leuprorelin Acetate SR 11.25 mg for Injection Specified Drug-use Survey "Long-term Use Survey on Premenopausal Breast Cancer Patients (96 Weeks)"
Takeda
Breast Cancer
Adjuvant Leuprolide With or Without Docetaxel in High Risk Prostate Cancer After Radical Prostatectomy
Sanofi
Prostatic Neoplasms
Understanding Experimentally Induced Hot Flushes
Massachusetts General Hospital
Hot Flashes
Melanoma Vaccine With Peptides and Leuprolide
M.D. Anderson Cancer Center
Melanoma
Leuplin SR 11.25 mg Injection Kit Specified Drug-use Survey "Long-term Use Survey in Prostate Cancer Patients (96 Weeks)"
Takeda
Prostate Cancer
Leuprolide Acetate 3.75 mg Depot to Treat Prostate Cancer
GP-Pharm
Prostate Cancer
Docetaxel, Androgen Ablation, and External-Beam Radiation Therapy in Patients With High-Risk Localized Prostate Cancer
UNC Lineberger Comprehensive Cancer Center
Prostate Cancer
Insulin Resistance and Testosterone in Women
University of Pennsylvania
Insulin Resistance · Postmenopause
Regulation of Cortisol Metabolism and Fat Patterning
Oregon Health and Science University
Obesity · Menopausal Syndrome
Neoadjuvant Hormones + Docetaxel in Node-Positive Prostate Cancer
M.D. Anderson Cancer Center
Prostate Cancer
Neoadjuvant Estradiol or Androgen Deprivation in Clinically Localized Prostate Cancer
University of Washington
Cancer · Prostate Neoplasms
Oral Androgens in Man-3 (ORAL T-3) Pharmacokinetics of Oral Testosterone
University of Washington
Contraception · Hypogonadism
External Beam Radiation Therapy (EBRT) With or Without Hormonal Therapy in Prostate Cancer
M.D. Anderson Cancer Center
Prostate Cancer
Comparison of the Operation and Medical Treatment of Endometriosis and Adenomyosis
Taipei Veterans General Hospital, Taiwan
Endometriosis · Adenomyosis
The Use of GnRH Agonist Trigger in the Prevention of OHSS
University of Connecticut
Ovarian Hyperstimulation Syndrome
Implant and External Radiation for Prostate Cancer With or Without Hormonal Therapy: A Prospective Randomized Trial
Schiffler Cancer Center
Prostate Cancer
Treatment of Endometriosis With Norethindrone Acetate ( NA) VS. Gonadotropin- Releasing Hormone (GnRH) Agonist (Lupron Depot 11.25 mg)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Endometriosis · Dysmenorrhea · Dyspareunia
A Study of Progenta (CDB-4124) in Pre-menopausal Women With Symptomatic Leiomyomata
Repros Therapeutics Inc.
Uterine Leiomyomata
Medical Treatment of Endometriosis-Associated Pelvic Pain
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Endometriosis · Pelvic Pain
Hormone Ablation Therapy, Doxorubicin, and Zoledronate With or Without Strontium 89 in Treating Patients With Androgen-Dependent Prostate Cancer and Bone Metastases
M.D. Anderson Cancer Center
Metastatic Cancer · Prostate Cancer
Study to Document Treatment Patterns and to Evaluate Leuprolide and Alternative Therapeutic Approaches to the Treatments of Advanced Prostate Cancer
Abbott
Prostatic Neoplasm
Hormone Therapy and Ipilimumab in Treating Patients With Advanced Prostate Cancer
Mayo Clinic
Prostate Adenocarcinoma · Prostate Carcinoma · Recurrent Prostate Carcinoma · Stage III Prostate Cancer
Long Acting LHRH Versus Short Acting LHRH in the Treatment of Prostate Cancer
University of British Columbia
Prostate Cancer
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
GnRH-a and Pregnancy Rate in In Vitro Fertilization (IVF) Cycles.
University of Ioannina
Endometriosis · Infertility
Androgen Suppression Combined With Elective Nodal and Dose Escalated Radiation Therapy
University of British Columbia
Prostate Cancer
Treatment of Hot Flushes Caused by Leuprorelin 11.25 mg in Prostate Adenocarcinoma
Takeda
Adenocarcinoma, Prostate
CP-675,206 With Neoadjuvant Hormone Therapy in Patients With High Risk Prostate Cancer
AstraZeneca
Prostatic Neoplasms
Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation (ALADDIN) VP 104 Study
Voyager Pharmaceutical Corporation
Alzheimer Disease
Clinical Trial for Prostate Cancer
Oakwood Laboratories, LLC
Prostate Cancer
Evaluate Recovery of Testosterone for Patients Using Eligard
Chesapeake Urology Research Associates
Prostate Cancer
RADAR Trial - Randomised Androgen Deprivation and Radiotherapy
Trans Tasman Radiation Oncology Group
Prostate Cancer
Polycystic Ovary Syndrome (PCOS) and Sleep Apnea
University of Chicago
Polycystic Ovary Syndrome · Obstructive Sleep Apnea
Cognitive and Hormonal Treatment of Sex Offenders
Norwegian University of Science and Technology
Paraphilia
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Docetaxel With Rapid Hormonal Cycling as a Treatment for Patients With Prostate Cancer
Memorial Sloan Kettering Cancer Center
Prostate Cancer
Hormonal Ablation, Imatinib Mesylate and Docetaxel for Patients With Prostate Cancer
M.D. Anderson Cancer Center
Prostate Cancer
Growth Hormone and GnRH Agonist in Adolescents With Acquired Hypothyroidism
Baylor College of Medicine
Hypothyroidism
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Zometa on Bone Mineral Density in Prostate Cancer Patients Undergoing Androgen Ablation Therapy
University of Wisconsin, Madison
Prostate Cancer
A Six-Month, Open-Label, Crossover Study Of the Maintenance Of Serum Testosterone And PSA Suppression After Switching Between Lupron 22.5 Mg And Eligard 22.5 Mg Or Zoladex 10.8 Mg And Eligard 22.5 Mg In Patients With Advanced Prostate Cancer
San Bernardino Urological Associates Medical Group Inc
Cancer of Prostate
Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF
Colorado Center for Reproductive Medicine
Endometriosis · Infertility
ALADDIN Study: Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation
Voyager Pharmaceutical Corporation
Alzheimer Disease
Study of a 6-Month Sustained-Release Formulation of Leuprolide Acetate in Prostate Cancer
Abbott
Prostatic Neoplasms
GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients
M.D. Anderson Cancer Center
Amenorrhea · Premature Ovarian Failure · Ovarian Function Insufficiency
Comparison of Trelstar Versus Lupron or Zoladex in Advanced Prostate Cancer
Pharmatech
Prostate Cancer
Exisulind and Intermittent Androgen Suppression (ADT) in Biochemical Relapsed Prostate Cancer
University of Washington
Prostate Cancer
Intensity-Modulated Radiation Therapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IV Prostate Cancer
Mayo Clinic
Prostate Cancer
Dydrogesterone or micronized progesterone related birth defects in children
Institute of Reproductive Medicine
Infertility, luteal phase support
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Hormone Therapy With or Without Squalamine Lactate in Treating Patients Who Are Undergoing a Radical Prostatectomy for Locally Advanced Prostate Cancer
OHSU Knight Cancer Institute
Prostate Cancer
S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer
SWOG Cancer Research Network
Prostate Cancer
SU5416 Plus Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer
University of Chicago
Prostate Cancer
Lupron Sex Offender Therapy
Schober, Justine, M.D.
Pedophilia
Rapid Hormonal Cycling as Treatment for Patients With Prostate Cancer: The Men's Cycle
Memorial Sloan Kettering Cancer Center
Prostate · Cancer · Hormonal Cycling
Chemotherapy, Hormone Therapy, and Radiation Therapy in Treating Patients With Locally Advanced Prostate Cancer
Alliance for Clinical Trials in Oncology
Prostate Cancer
A prospective study to compare immediate with deferred treatment in advanced, localised and asymptomatic metastatic newly diagnosed prostatic carcinoma
Medical Research Council (MRC) (UK)
Prostate cancer
Leuprolide, Bicalutamide, and Implant Radiation Therapy in Treating Patients With Locally Recurrent Prostate Cancer After External-Beam Radiation Therapy
Mayo Clinic
Prostate Cancer
Leuprorelin Associated With Radiotherapy Versus Leuprorelin Alone in T3 - T4 or pT3 (on Biopsy) N0, M0 Prostate Cancer
Takeda
Prostatic Neoplasms, Locally Advanced
Thalidomide for the Treatment of Hormone-Dependent Prostate Cancer
National Cancer Institute (NCI)
Prostate Cancer
Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer
Radiation Therapy Oncology Group
Prostate Cancer
Randomized Trial of Adjuvant Hormonal Therapy in Surgically Treated Prostate Cancer Patients at High Risk for Recurrence
M.D. Anderson Cancer Center
Prostate Cancer
Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer
NCIC Clinical Trials Group
Prostate Cancer
Combination Chemotherapy in Treating Patients With Advanced Prostate Cancer
Memorial Sloan Kettering Cancer Center
Prostate Cancer
Leuprolide in Treating Adults With Hypogonadotropism
University of Chicago
Hypogonadism
Radiation Therapy With Androgen Suppression in Treating Patients With Prostate Cancer
Alliance for Clinical Trials in Oncology
Prostate Cancer
Hormone Therapy Plus Radiation Therapy in Treating Patients With Prostate Cancer
Herbert Irving Comprehensive Cancer Center
Prostate Cancer
Effects of IAS in Men With Localized Biochemical Relapsed Prostate Cancer
University of Washington
Prostate Cancer
Purification of Testis-Stimulating Factor in Precocious Puberty
National Center for Research Resources (NCRR)
Precocious Puberty
Intermittent Hormonal Therapy With Leuprorelin and Flutamide in the Treatment of Stage D2 or TxNxM1b,c
Takeda
Prostatic Neoplasms
Flutamide, Suramin, and Hydrocortisone in Treating Patients With Prostate Cancer
Eastern Cooperative Oncology Group
Prostate Cancer
The Role of Hormones in Postpartum Mood Disorders
National Institute of Mental Health (NIMH)
Postpartum Depression
Three Drug Combination Therapy Versus Conventional Treatment of Children With Congenital Adrenal Hyperplasia
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Congenital Adrenal Hyperplasia (CAH)
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Hormone Therapy With or Without Surgery or Radiation Therapy in Treating Patients With Prostate Cancer
NCIC Clinical Trials Group
Prostate Cancer
Radiation Therapy With or Without Antiandrogen Therapy in Treating Patients With Stage I or Stage II Prostate Cancer
Radiation Therapy Oncology Group
Prostate Cancer
Leuprolide in Determining the Cause of Gonadotropin Deficiency
University of Chicago
Hypogonadism
The Effects of Reproductive Hormones on Mood and Behavior
National Institute of Mental Health (NIMH)
Healthy Volunteers
Randomized Study of Hormonal Regulation of Infantile Hemangioma
FDA Office of Orphan Products Development
Hemangioma
Tamoxifen, Ovarian Ablation, and/or Combination Chemotherapy in Treating Premenopausal Women With Stage I, Stage II, or Stage IIIA Invasive Breast Cancer
Scottish Cancer Therapy Network
Breast Cancer
Tamoxifen, Ovarian Ablation, and/or Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer
Institute of Cancer Research, United Kingdom
Breast Cancer
Phase II Randomized Study of Leuprolide Vs Oral Contraceptive Therapy Vs Leuprolide and Oral Contraceptive Therapy for Ovarian Hyperandrogenism
National Center for Research Resources (NCRR)
Hyperandrogenism
Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease
National Center for Research Resources (NCRR)
Spinal Muscular Atrophy · Amyotrophic Lateral Sclerosis · Spinobulbar Muscular Atrophy
A Treatment Study for Premenstrual Syndrome (PMS)
National Institute of Mental Health (NIMH)
Premenstrual Syndrome · Menstruation Disturbances
Study of Lupron Depot In The Treatment of Central Precocious Puberty
Abbott
Puberty, Precocious
Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome
National Center for Research Resources (NCRR)
Acanthosis Nigricans · Polycystic Ovary Syndrome
Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Prostate Cancer
Burzynski Research Institute
Adenocarcinoma of the Prostate · Stage III Prostate Cancer · Stage IV Prostate Cancer · Recurrent Prostate Cancer
Analysis of Genetic and Environmental Parameters Influencing Growth Rate of Precocious Puberty Children
University of Pisa
Central Precocious Puberty
202000894
Universitair Medisch Centrum Groningen
polycystic liver disease
The JET Study: a Phase I Trial of Cabazitaxel, Radiotherapy and Long-term Androgen Deprivation
Nova Scotia Cancer Centre
Prostatic Neoplasms
Named in the study description rather than as the headline intervention — often a drug given alongside the one being tested.
Sources: ClinicalTrials.gov, the EU Clinical Trials Information System and ISRCTN, deduplicated so a study registered in more than one registry is counted once. A study is listed when Leuprolide is named as an intervention. A registered trial is a plan, not a result — registration says nothing about whether the peptide worked.