Myristoyl Pentapeptide-17 dosing & administration
Keratin-stimulating lipopeptide specifically designed to enhance eyelash and eyebrow growth through hair follicle activation.
Written by Michael Carroll — Owner, Director of Research · Reviewed by the Peptide Initiative Research Team · Editorial standards
Dosing
How much do I take?
Topical: Applied onto the skin as a cream, gel, or lotion — it works mainly where you put it.
Bioavailability Local — acts mainly at the skin; little reaches the bloodstream.
0.001-0.1% in finished serum (supplied as a 0.1% / 1000 ppm active solution)
Frequency
Once or twice daily to lash line / brows
Duration
8-16 weeks for visible lash effect
Cosmetic lash/brow active applied to the lash line; typical eye-area use concentrations and the 1000 ppm supplier solution define the formulation dose [6]. Topical only; not dosed systemically.
Timing
Best time to take
Apply Myristoyl Pentapeptide-17 to clean, dry skin. For best results, use consistently at the same time(s) each day. Evening application is often preferred to allow overnight absorption, unless otherwise directed.
With food?
As a topical product, Myristoyl Pentapeptide-17 is not affected by food intake. Apply to clean skin and allow adequate absorption time before covering the area.
If stacking
Myristoyl Pentapeptide-17 should be used as directed by your healthcare provider. If combining with other medications or supplements, discuss potential interactions with your provider. Avoid combining with compounds that have overlapping mechanisms unless specifically guided by a medical professional.
Adjusting your dose
Increase if
- You've tolerated the current dose for the recommended period without significant side effects
- Therapeutic goals haven't been met at the current dose level
- Your healthcare provider recommends dose escalation based on your response
- Lab work or clinical assessments support a higher dose
Decrease if
- Side effects are bothersome or impacting daily life despite management strategies
- You experience any signs of an adverse reaction
- Lab results indicate the need for dose reduction
- Your healthcare provider recommends a lower dose based on your response
Signs of right dose
- Therapeutic goals being met with minimal side effects
- Stable and consistent response to treatment
- Lab values or clinical markers trending in the right direction
- Good tolerance with manageable or absent side effects
Administration
How do I use it?
Reconstitution
What you need
Injection
Route
Myristoyl Pentapeptide-17 is administered Topical—no injection required
Best sites
Storage
Before reconstitution
Store Myristoyl Pentapeptide-17 in the refrigerator at 36-46°F (2-8°C) in its original packaging. Protect from light and moisture. Do not freeze. Check the expiration date before use. Some formulations may be stored at room temperature for limited periods—check your specific product labeling.
After reconstitution
Once reconstituted, Myristoyl Pentapeptide-17 should be kept refrigerated at 36-46°F (2-8°C) and used within the timeframe specified on your product labeling (typically 14-28 days). Label the vial with the reconstitution date. Do not use if the solution appears cloudy, discolored, or contains particles.
Signs of degradation — discard the vial
Sample daily schedule
As prescribed (once daily)
As prescribed by your healthcare provider injection
Site: Topical—rotate sites if applicable
Maintain a consistent schedule for optimal results with Myristoyl Pentapeptide-17. Set reminders if needed. If you miss a dose, follow your healthcare provider's instructions—do not double up on doses to compensate.
Safety
Is it safe?
Side effects
Commonly reported: Mild Tingling at Lash Line, Temporary Eyelid Dryness, Product Residue Buildup, Lash Shedding During Initial Phase
Less common: Periorbital Sensitivity
Stop and seek help if
- Severe or worsening side effects that don't improve with dose adjustment or supportive care
- Signs of an allergic reaction—rash, hives, swelling, or difficulty breathing
- Your healthcare provider recommends discontinuation based on your clinical response
- Development of any new medical condition that may be contraindicated with Myristoyl Pentapeptide-17
- Pregnancy or planning to become pregnant (unless specifically approved for use during pregnancy)
- Abnormal lab results or clinical markers that suggest adverse effects
Myristoyl Pentapeptide-17 should only be started, adjusted, or discontinued under medical supervision. This information is for educational purposes only and does not replace professional medical advice. Never stop a prescribed treatment without consulting your healthcare provider first, as abrupt discontinuation may have consequences.
Flagged pairings
- Prostaglandin Analogs (bimatoprost, latanoprost) — Use with caution—discuss with your healthcare provider.
- High-concentration Retinoids near the eye — Use with caution—discuss with your healthcare provider.
- Waterproof Mascara (directly over wet serum) — Use with caution—discuss with your healthcare provider.
Published research
What the studies show
Fernandez-Gonzalez P, et al. · 2024
A 12-week clinical trial of an eyelash growth enhancer showed dramatic improvements: lash length increased 8.3%, number increased 5%, width increased 10.1%, volume surged 14.1%. Patient satisfaction reached 84.33%.
Lee JO, et al. · 2024
AP collagen peptides promoted hair growth by activating the GSK-3β/β-catenin pathway, increasing follicle elongation and stimulating new hair shaft induction in mice. Hair thickness and amino acid content improved significantly.
Kim Y, et al. · 2024
Low molecular weight collagen peptides activated the Wnt/β-catenin pathway, promoting hair growth through dermal papilla cell activation. Oral administration to mice significantly stimulated hair growth with elevated gene expression.
Akanda MR, et al. · 2017
Keratin extract topically applied promoted hair growth by inducing the anagen growth phase in telogenic mice, increasing follicle number. More than 90% cell viability was maintained, proving biocompatibility.
Loing E, Lachance R, Ollier V, et al. · 2013
A placebo-controlled trial of peptide plus plant extract increased anagen hair 13%, decreased telogen hair 29%, raised anagen/telogen ratio 46% after 4 months. Results differed dramatically from placebo.
Cosmetic Ingredients Guide · 2024
Lipo-oligopeptide eyelash enhancer supplied as a 1000 ppm (0.1%) bioavailable solution; used in eye-area lash/brow serums at low finished-product concentrations.
Head to head
Myristoyl Pentapeptide-17 compared
Want the full picture?
The complete Myristoyl Pentapeptide-17 research profile: mechanism of action, clinical studies, effectiveness timeline, and FAQ.