Immunoxel (Dzherelo) dosing & administration
Ukrainian botanical immunomodulator that supercharges tuberculosis treatment and restores immune function in HIV patients
Written by Michael Carroll — Owner, Director of Research · Reviewed by the Peptide Initiative Research Team · Editorial standards
Dosing
How much do I take?
Oral: Taken by mouth as a capsule, tablet, or liquid.
Bioavailability Varies by compound — many peptides are largely broken down in the gut, so little reaches the blood intact; some small molecules absorb well.
Timing
Best time to take
Morning and evening doses, spaced approximately 12 hours apart
With food?
Can be taken with or without food; sublingual lozenges dissolve under the tongue regardless of meals
If stacking
Take alongside standard TB medications as prescribed; no timing conflicts with anti-TB drugs reported in clinical trials
Adjusting your dose
Increase if
- Well-tolerated at starting dose after 1-2 weeks with no GI issues
- Sputum conversion has not occurred after 4 weeks of standard therapy
- Healthcare provider recommends advancing to combination protocol with Anemin
Decrease if
- Experiencing persistent gastrointestinal discomfort
- Mild allergic symptoms appear (skin rash, itching)
- Nausea that doesn't resolve within the first few days
Signs of right dose
- Sputum smear conversion to negative within 1-2 months
- Weight gain and improved appetite
- Reduced fever and improved energy levels
- Rising CD4+ T-cell counts on blood tests (in HIV patients)
Administration
How do I use it?
Reconstitution
What you need
Injection
Route
N/A — Immunoxel is taken orally or sublingually, NOT by injection
Best sites
Storage
Before reconstitution
Store sealed bottles and packages at room temperature (15-25°C), protected from direct sunlight and excessive heat. Keep in original packaging.
After reconstitution
N/A — Immunoxel does not require reconstitution. Once opened, keep bottle tightly sealed and use within the shelf life printed on the label.
Signs of degradation — discard the vial
Sample daily schedule
Morning
50 drops (oral liquid) OR 1 sublingual lozenge injection
Site: Oral or sublingual
Take with or without food; if using liquid, can mix with small amount of water
Evening
50 drops (oral liquid only — sublingual is once daily) injection
Site: Oral
Second dose approximately 12 hours after morning dose; sublingual users skip this dose
Safety
Is it safe?
Side effects
Commonly reported: Well-tolerated in most patients, Mild gastrointestinal discomfort
Less common: Temporary taste changes, Mild allergic skin reactions, Mild headache
Stop and seek help if
- Signs of allergic reaction (widespread rash, swelling, difficulty breathing)
- Persistent gastrointestinal problems that don't resolve within a week
- Your doctor advises discontinuation due to medication interactions
- Completion of your TB treatment course (Immunoxel is typically used for the duration of TB therapy)
- Worsening of symptoms despite continued use (consult your medical team)
Always consult your healthcare provider before starting or stopping Immunoxel. This product should only be used as an adjunct to standard medical treatment, never as a replacement. It is not FDA approved and is primarily available in Ukraine.
Flagged pairings
- Immunosuppressants — May counteract immunosuppressive effects; avoid combining without specialist guidance
- Warfarin and blood thinners — Some herbal components may affect coagulation; monitor INR closely
- Oral contraceptives — St. John's Wort in the formulation may reduce effectiveness of hormonal birth control
Published research
What the studies show
Hariyanto TI et al. · 2021
When researchers combined data from 6 TB studies involving nearly 500 patients, Immunoxel boosted the power of standard TB drugs by more than threefold, making patients three times more likely to clear the infection. The herbal supplement also dramatically reduced fevers while helping the body fight back against the bacteria.
Efremenko YV, Arjanova OV, Prihoda ND et al. · 2012
TB patients who let Immunoxel dissolve under their tongue cleared their lungs at a rate of 84% in just one month, versus only 19% in patients taking placebo. Remarkably, the herbal helper worked equally well regardless of age, weight, gender, or whether the TB was drug-resistant or combined with HIV.
Arjanova OV, Prihoda ND, Yurchenko LV et al. · 2009
In patients suffering from both TB and HIV, adding Immunoxel to standard TB drugs quadrupled their chances of clearing the infection (from 16% to 67%) and cut secondary infections from 12 down to 3. Patients also gained nearly 6 pounds, reversing the severe weight loss typical of dual infection.
Nikolaeva LG, Maystat TV, Masyuk LA et al. · 2009
The herbal extract Immunoxel alone—without any antiretroviral drugs—expanded patients' HIV-fighting CD4 cells by 71%, jumping from 174 to 283 cells in just 2 months and reducing HIV copies in 70% of those treated. This suggests the botanical blend awakens the immune system's dormant power.
Nikolaeva LG, Maystat TV, Pylypchuk VS et al. · 2008
Immunoxel works by tuning the immune orchestra—ramping up the protective chemical signals IL-2 and interferon-gamma by 61%, while silencing the inflammatory alarm bells TNF-alpha. This immune rebalancing allows the body to mount an effective counterattack against tuberculosis.
Head to head
Immunoxel (Dzherelo) compared
Want the full picture?
The complete Immunoxel (Dzherelo) research profile: mechanism of action, clinical studies, effectiveness timeline, and FAQ.