Weight Management Protocol
AdipotideComplete Dosing & Administration Guide
A targeted fat-destroying peptide that works like a smart missile, cutting off blood supply to fat cells and causing rapid weight loss in primate studies.
Dose Range
0.1-0.43mg/kg
Frequency
Once daily
Route
Subcutaneous injection
Cycle Length
4-6 weeks
Dosing
How much
do I take?
Starting Dose
0.1 mg/kg
Begin with the lowest effective dose to assess tolerance and monitor kidney function. This cautious approach helps identify any sensitivity before progressing.
Standard Dose
0.25 mg/kg
This intermediate dose showed good efficacy with manageable side effects in primate studies. Regular monitoring of renal markers is essential.
Advanced Dose
0.43 mg/kg
The optimal therapeutic dose identified in primate studies. Produced average 11% body weight loss in 4 weeks. Requires close kidney monitoring and adequate hydration.
Timing
Best time to take
Morning, at a consistent time each day
With food?
Can be administered with or without food. Ensure adequate hydration throughout the day.
If stacking
If using BPC-157 for potential renal support, administer at a different time of day. Avoid combining with other nephrotoxic substances.
Adjusting Your Dose
Increase if
- +Tolerating current dose well with stable kidney markers
- +Minimal side effects after 1-2 weeks
- +Fat loss progress has plateaued at current dose
- +Serum creatinine remains within normal range
Decrease if
- -Serum creatinine rises above normal range
- -Significant proteinuria or glucosuria develops
- -Signs of dehydration despite adequate fluid intake
- -Any concerning changes in urination patterns
Signs of right dose
- ✓Steady fat loss of 2-3% body weight per week
- ✓Stable kidney function markers
- ✓Improved insulin sensitivity on bloodwork
- ✓No significant side effects
Dosing Calculator
Calculate Your Exact Dose
Step 1: Peptide Weight
Find the weight printed on your peptide vial label
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The peptide weight is printed on the label
Look here!
The weight is on the label
Administration
How do I
use it?
Reconstitution
What you need
- •Bacteriostatic water (BAC water)
- •Insulin syringe (29-31 gauge)
- •Alcohol swabs
- •Sterile vial of Adipotide powder
- •Calculator for dose calculation based on body weight
Injection
Route
Subcutaneous injection once daily
Best sites
- •Abdomen (2 inches from navel)
- •Front of thigh (middle third)
- •Upper arm (outer area)
Technique
- 1.Calculate your dose based on body weight and verify the math
- 2.Clean injection site thoroughly with alcohol swab and let dry
- 3.Pinch skin to create a fold at the injection site
- 4.Insert needle at 45-90 degree angle depending on body composition
- 5.Inject slowly and steadily
- 6.Remove needle and apply light pressure - do not rub
Storage
Signs of degradation
Sample Daily Schedule
Safety
Is it
safe?
Safety Profile
Adipotide has been extensively studied in mice, rats, and three species of primates with consistent results. The primary safety concern is dose-dependent kidney effects, which were reversible upon stopping treatment in all studies. No cardiovascular, neurological, or hepatic adverse events were observed. The compound shows remarkable selectivity - lean animals given the same doses experienced no weight loss, suggesting it specifically targets excess fat tissue.
Safety data comes from well-designed primate studies published in peer-reviewed journals including Science Translational Medicine. However, there are no human clinical trials, so the full safety profile in humans remains unknown. The reversibility of kidney effects in primates is encouraging but requires validation in human studies.
Common Side Effects
Experienced by some users
Elevated Serum Creatinine
The most consistently observed effect in primate studies, indicating the kidneys are processing the compound.
Management: Monitor with regular blood tests. Usually normalizes within 4 weeks of stopping treatment. Stay well-hydrated.
Proteinuria
Mild to moderate protein appearing in urine, reflecting kidney filtration changes.
Management: Monitor with urinalysis. Reduce dose if marked. Ensure adequate hydration.
Glucosuria
Glucose appearing in urine even with normal blood sugar, due to effects on kidney tubules.
Management: Monitor blood glucose to ensure it remains normal. Not typically concerning if blood sugar is stable.
Reduced Appetite
Decreased food intake observed in all treated animals - appears to be genuine appetite reduction rather than nausea.
Management: Ensure adequate protein intake despite reduced appetite. This effect contributes to weight loss.
Less Common
- •Mild Dehydration
- •Injection Site Reactions
These typically resolve with continued use or dose adjustment.
Stop and Seek Help If
- ×Serum creatinine rises significantly above your baseline
- ×Marked proteinuria that persists or worsens
- ×Signs of kidney problems (pain in lower back, changes in urination)
- ×Severe or persistent dehydration despite adequate fluid intake
- ×Any allergic reaction (rash, swelling, difficulty breathing)
- ×Completion of the recommended 4-week treatment cycle
Adipotide is a research compound without FDA approval. Use only under medical supervision with regular kidney function monitoring. Stop immediately and consult a healthcare provider if you experience any concerning symptoms.
Interactions
With other peptides
- ✓May provide protective effects for kidneys - consider using for support
- ✓No known interactions, but avoid adding kidney stress
- !Both target fat loss through different mechanisms - use caution with combination
- !Different mechanisms but overlapping goals - not recommended to combine
With medications
- !NSAIDs (Ibuprofen, etc.) - Can compound kidney stress - avoid during Adipotide use
- !ACE Inhibitors - May affect kidney function - monitor closely if combining
- !Diuretics - Increases dehydration risk significantly - avoid combination
- ✓Metformin - Generally safe but monitor kidney function more frequently
With supplements
- ✓Electrolytes - Highly recommended to maintain proper hydration and mineral balance
- ✓Protein supplements - Recommended to preserve muscle mass during rapid fat loss
- ✓Creatine - May confound creatinine monitoring - consider stopping during treatment
- ✓High-dose Vitamin C - Very high doses may affect kidney stone risk - use moderate amounts
Want the Full Picture?
View the complete Adipotide research profile including mechanism of action, clinical studies, effectiveness timeline, and FAQ.
View Full Adipotide Profile