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Injection Guide
A supercharged version of your body's own growth factor that stays active 2-3 times longer than regular IGF-1, making it a powerhouse for muscle growth, recovery, and cellular regeneration.
Route
Subcutaneous
Sites
4 recommended
Frequency
Once daily
Preparation
Bacteriostatic water (BAC water)—the benzyl alcohol preservative keeps it sterile for multiple uses
Insulin syringes (29-31 gauge)—1mL syringes with 100 unit markings work best
Alcohol swabs for cleaning vial tops and injection sites
Your IGF-1 LR3 powder vial (typically 1mg/1000mcg)
Pro Tip
Prepare all supplies on a clean surface before you begin. Having everything ready makes the process smoother and more sterile.
Mixing
Wash your hands thoroughly with soap and water. Gather all supplies on a clean, flat surface.
Remove the plastic cap from the peptide vial and wipe the rubber stopper with an alcohol swab. Let it air dry.
Draw the appropriate amount of bacteriostatic water into a sterile syringe.
Insert the needle into the vial at an angle, aiming at the inside wall of the vial. Slowly push the plunger to let the water trickle down the glass wall -- do NOT squirt directly onto the powder.
Once all water is added, gently swirl the vial in a slow circular motion. Never shake the vial, as this can damage the peptide bonds.
Continue swirling until the powder is completely dissolved and the solution is clear. If particles remain, let the vial sit for a few minutes and swirl again.
Label the vial with the date of reconstitution, the peptide name, and the concentration (e.g. 250mcg per 0.1mL).
Example Calculation
If you have a 1mg (1000mcg) vial and add 2mL of BAC water, you get a concentration of 500mcg/mL. So every 0.1mL (10 units on an insulin syringe) equals 50mcg of IGF-1 LR3.
Dose Calculation
For a 50mcg dose at 500mcg/mL: draw 0.1mL (10 units). For 100mcg: draw 0.2mL (20 units). Always double-check your math—this peptide is potent!
Pro Tip
Always add the bacteriostatic water slowly, letting it run down the side of the vial. Never shake the vial -- swirl gently to avoid damaging the peptide.
Location
Site 01
Abdomen
Pinch the skin 2 inches from navel. Avoid the area directly around the belly button. Rotate between left and right sides.
Site 02
Target muscle (bicep, quad, etc.)—for site-specific enhancement
Follow your provider's instructions for this injection site. Rotate sites regularly to prevent tissue damage.
Site 03
Outer Thigh
Middle third of the outer thigh. Keep at least 4 inches above the knee and below the hip. Alternate legs each injection.
Site 04
Upper Arm
Back or outer area of the upper arm. This site may require assistance from another person for proper technique.
Rotate between 4 sites to prevent tissue buildup and ensure consistent absorption.
Pro Tip
Rotate your injection sites with each dose to prevent lipohypertrophy (buildup of fatty tissue). Keep a simple log of where you last injected.
Step by Step
Wash your hands thoroughly with soap and water
Clean the injection site with an alcohol swab, let it air dry completely
For subcutaneous: pinch about an inch of skin and insert at 45-90 degrees
For intramuscular: insert straight into the muscle belly at 90 degrees
Inject slowly and steadily—rushing can cause more discomfort
Wait 5-10 seconds before withdrawing the needle
Apply light pressure if needed, but don't rub the site
Pro Tip
This peptide uses subcutaneous injection (under the skin) is most common; intramuscular injection into specific muscles is also used for localized effects. Inject at a 45-90 degree angle into pinched skin. Aspirate before injecting to ensure you haven't hit a blood vessel.
Timing
Optimal Timing
Best time
Post-workout is ideal for training days—your muscles are like sponges ready to absorb nutrients. On rest days, morning with breakfast works well. Some users split doses between pre and post-workout.
With food?
Always have food available! IGF-1 LR3 can cause significant blood sugar drops. Eat a meal with protein and carbs within 30 minutes of injection. Never inject fasted unless you're very experienced.
Stacking notes
If stacking with growth hormone (HGH), inject IGF-1 LR3 at least 2-3 hours apart to avoid competition for receptors. Can be combined with MGF for potentially synergistic muscle-building effects.
Sample Daily Schedule
Post-workout (within 30 minutes of finishing)
40-80 mcg depending on experience level injection
Site: Subcutaneous near abdomen or intramuscular into trained muscle
Training days: inject immediately after workout when muscles are primed for nutrient uptake. Have a protein and carb meal ready within 30 minutes to prevent hypoglycemia and maximize anabolic effect.
Morning with breakfast (rest days)
Same dose as training days injection
Site: Subcutaneous near abdomen
Rest days: inject with your morning meal. Continue cycles for 4-6 weeks, then take at least 4 weeks off to allow receptor sensitivity to reset. Some users do 5 days on, 2 days off.
Dosing Tiers
Dose
20-40 mcg
Frequency
Once daily
Duration
2-3 weeks
Start low to assess your body's response and learn how you handle the blood sugar effects. Many people find even small doses quite effective. Always have a carbohydrate source nearby when starting.
Dose
40-80 mcg
Frequency
Once daily
Duration
4-5 weeks
The sweet spot for most users seeking noticeable results. Inject post-workout on training days for maximum benefit, as muscles are primed to absorb nutrients. On rest days, inject in the morning with breakfast.
Dose
80-100 mcg
Frequency
Once daily
Duration
4 weeks maximum
Higher doses increase results but also increase side effect risk, especially hypoglycemia. Split dosing (half pre-workout, half post-workout) can help manage blood sugar. Requires strict attention to nutrition timing.
Preservation
Before Mixing
Keep your IGF-1 LR3 powder refrigerated at 36-46°F (2-8°C) for storage up to 1 month. For longer storage, freeze at -4°F (-20°C) or below. The powder is quite stable when kept cold and away from light.
After Mixing
Once mixed with bacteriostatic water, refrigerate at 36-46°F (2-8°C). Never freeze the mixed solution—ice crystals will destroy the peptide structure. Keep away from light and use within 28-30 days.
Shelf Life After Mixing
28-30 days
Signs of Degradation
Discard the vial immediately if you notice any of these:
Cloudy or hazy solution (should be crystal clear)
Visible particles floating or settled at bottom
Any color change—fresh solution is colorless
Unusual smell—properly reconstituted peptide has minimal odor
Important
When to Stop
Any severe hypoglycemic episode that doesn't resolve quickly with food
Persistent numbness, tingling, or carpal tunnel symptoms
Joint pain that interferes with training or daily activities
Signs of allergic reaction (rash, swelling, difficulty breathing)
Any concerning or unusual symptoms that worry you
Completion of your planned cycle (typically 4-6 weeks)
IGF-1 LR3 is a research compound, not approved for human therapeutic use by the FDA. This information is for educational purposes only and not medical advice. Always consult with a healthcare provider before starting, stopping, or modifying any research protocol.
Clean Technique Checklist
Wash hands thoroughly with soap and water before handling supplies
Swab vial tops and injection site with alcohol and let dry
Never touch the needle tip or allow it to contact non-sterile surfaces
Use a new syringe and needle for each injection
Dispose of used sharps in a proper sharps container
Store reconstituted peptides according to the storage instructions above