Clinical trials
Every registered trial of Glutathione
94 studies, 17 still enrolling.
Plain-Language Summary
Plain-language reading of the public trial registries.
In short
- Glutathione has a real but limited body of human research.
- 94 registered studies in total.
- 17 are still enrolling people, so this is active research, not just history.
What kind of research
- 91 studies actually gave the peptide to volunteers and measured what happened. This is the kind of study that can show whether something works.
- About 7,062 people took part in those.
- A further 3 studies only looked at records of people already taking it. These are counted separately because nobody was given the peptide for the study, so they cannot prove cause and effect.
How far along it is
- 10 trials have reached phase 3 or 4 — the large, late-stage trials regulators rely on to approve a drug.
- 20 have published results in the medical literature that anyone can read.
- The research spans 21 countries.
A registered trial is a plan, not a result. Registration means a study was declared in advance; it says nothing about whether the peptide worked, and a trial can be registered and then abandoned.
Filter
Showing 94 of 94 trials for Glutathione.
S-Acetyl Glutathione and Performance Recovery in Soccer
University of Thessaly
Performance Recovery · Exercise-induced Inflammation · Exercise-induced Oxidative Stress
Weight Gain in Pediatric Leukemia Survivors
Washington University School of Medicine
Leukemia · Pediatric Acute Lymphoblastic Leukemia · Pediatric Acute Lymphoblastic Leukemia in Remission · Pediatric Obesity
GAIP ASD Research Study
Greater Atlanta Integrative Pediatrics
Autism Spectrum Disorder · Autism · ASD · Autism Spectrum Disorder (ASD)
Adia Med of Winter Park LLC Chronic Kidney Disease Research Study
Adia Med of Winter Park LLC
Chronic Kidney Disease · Kidney Disease · Kidney Disease, Chronic · Chronic Kidney Disease (CKD)
Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study
Adia Med of Winter Park LLC
Autism Spectrum Disorder · Autism · ASD · Autism Spectrum Disorder (ASD)
Guided Self Help for Eating Disorders Implementation Study
McMaster University
Eating Disorders
Evaluation of the Efficacy of Oral Tranexamic Acid and Glutathione-assisted Microneedling in Treatment of Melasma
Assiut University
Melasma
Efficacy Evaluation Study of Vitamin C and Glutathione Liquid Sachet
TCI Co., Ltd.
Skin Condition · Anti-Oxidative Stress
Effect of Double Nutri® Liposomal Encapsulation Technology on Human Absorption of Vitamin C and Glutathione Liquid Sachet
TCI Co., Ltd.
Vitamin C · Glutathione
The Impact of Qualia Gluthathione+ on Blood Glutathione Levels
Qualia Life Sciences
Effects of Qualia Glutathione+ on Blood Glutathione Levels · Glutathione
Clinical Study to Assess Safety, Efficacy and In-Use Tolerability of Oziva Bioactive Gluta Fizzy Effervescent Tablets on Subjects With Facial Dark Spots Such as Pimple Marks, Sunspots, Age Spots and Uneven Skin Tone
NovoBliss Research Pvt Ltd
Hyperpigmentation
Gingival Hyperpigmentation Treatment
Cairo University
Gingival Pigmentation · Depigmentation · Vitamin C · Glutathione
Effectiveness of CAT-GSH for Returning Patients
University of Sheffield
Anxiety · Depression
Combination Gerotherapeutic Interventions for Healthspan Improvement
AgelessRx
Healthspan Improvement · Aging · Longevity
Comparison of Gingival Depigmentation Using Microneedling and Microneedling With Glutathione Gel - A Split Mouth Clinical Trial
Krishnadevaraya College of Dental Sciences & Hospital
Gingiival Hyperpigmentation
Glucocorticoids for Acute Drug Induced Liver Injury With Hyperbilirubinemia
General Hospital of Shenyang Military Region
Drug Induced Liver Injury
The Role of Glutathione Deficiency and MSIDS Variables in Long COVID-19
University of California, Irvine
COVID-19
Comparison of Effectiveness of Tranexamic Acid Mesotherapy Versus Glutathione Mesotherapy in Post Burn Facial Hyperpigmentation
King Edward Medical University
Post Burn Facial Hyperpigmentation
Randomized Trial of Glutathione With Anti-PD-1 and Chemotherapy in Advanced NSCLC
The First Affiliated Hospital of Zhengzhou University
Non-Small Cell Lung Cancer · Chemotherapy · PD1 Antibody · Glutathione
A study on whether a natural sulforaphane supplement can boost glutathione levels
DoNotAge.org
Effects of glucoraphanin and myrosinase supplementation on glutathione levels in middle-aged adults
Lactoferrin Effect on Kidney and Heart of Rhabdomyolysis Rats
Aswan University Hospital
Rhabdomyolysis
Ultrasound-Enhanced Delivery of Compound TXA Solution in Melasma
The First Affiliated Hospital with Nanjing Medical University
Melasma (Facial Melasma)
Integrative Intervention Strategies for Binge Eating in Patients With Overweight or Obesity
G. d'Annunzio University
Binge Eating · Overweight and Obesity
Prevent Cardiac Surgery Associated AKI Trial
George Washington University
Renal Failure · Coronary Artery Disease · Surgery · Surgery-Complications
Streptococcus Salivarius K12@Lip@GSH Alleviates Oral Mucositis in Patients Undergoing Radiotherapy
The General Hospital of Western Theater Command
Oral Mucositis
INTERCEPT Safety Evaluation on Whole Blood
Swiss Transfusion SRC
Safety Issues
The Impact of Oral Glutathione on Oxidative Damage and Glycated Hemoglobin (HbA1c) Levels in Type 2 Diabetes Patients
S.LAB (SOLOWAYS)
Type 2 Diabetes
Confirming the Effectiveness of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa
Stanford University
Anorexia Nervosa
Cognitive Analytic-Informed Guided Self-help for Depression
University of Sheffield
Depression
Effectiveness of a food supplement on skin, hair and nail condition
BCF Life Sciences
Visible face roughness and mild to moderate skin slackness, brittle nails and damaged/brittle hair
Pharmacokinetics and Safety of a New Micellar Glutathione Formulation
Factors Group of Nutritional Companies Inc.
Bioavailability Heathy Volunteers · Safety
Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease
Gateway Institute for Brain Research
Parkinson Disease
Glutathione (GSH) Supplementation After Hospitalization
Emory University
Malnutrition
The Role of Antioxidant Supplementation in Keratoconus Patients
University of Miami
Keratoconus
Effect of Glutathione vs KI in Reducing SDF Staining When Used in Treatment of Primary Carious Teeth
Cairo University
Discoloration, Tooth
Evaluation of the Relationship Between Oxidative Stress and Human Reproduction
Calla IVF Center
IVF · Pregnancy · Oxidative Stress · Fertility Disorders
Avatrombopag in Patients With End-stage Liver Disease and Thrombocytopenia
Tongji Hospital
Liver Failure · Thrombocytopenia · Decompensated Cirrhosis
Glutathione-rich Foods for Type 2 Diabetes
University of California, San Diego
Type 2 Diabetes
SH-SS and GSH-GSSG Homeostasis in Post-stroke Patients
Abant Izzet Baysal University
Stroke
Effect of 4 Weeks of Citrulline and Glutathione Supplementation on Arterial Function
Texas Tech University
Menopause · Cardiovascular Risk Factor
Treatment of Patients With Periorbital Hyperpigmentation
Sohag University
Periorbital Hypermelanosis
Setria Performance Blend Supplementation
University of North Carolina, Chapel Hill
Healthy
Feasibility Study Comparing Standard FBT and Guided Self-Help FBT for Adolescent Anorexia Nervosa
Stanford University
Anorexia Nervosa
A Study of Glutathione in Children With Autism Spectrum Disorder
University of Chicago
Autism Spectrum Disorder
Central Glutathione Levels in Women With Late Life Depression: a Cross Sectional Pilot Feasibility Study
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Female, Late Life Depression
Effects of Glutathione on Immunity in Individuals Training for a Marathon
University of North Texas, Denton, TX
Healthy
Oral Glutathione As A Skin Whitening Agent
Dr Irma Bernadette S Sitohang
Glutathione · Skin Whitening
Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection
Baylor College of Medicine
Hookworm Infections
Signaling Pathways Targeting Colorectal Cancer in Egypt
Assiut University
Colorectal Cancer
The Role of Oral Glutathione on Growth Parameters in Children With Cystic Fibrosis
University of Minnesota
Cystic Fibrosis
Project BITE: Binge Intervention Target Effectiveness
Drexel University
Binge-Eating Disorder
The Production of Reactive Oxygen Species in Response to Glutathione Supplementation and Acute Exercise
University of Copenhagen
Type 2 Diabetes · Oxidative Stress · Mitochondrial Reactive Oxygen Species Production
Noom Monitor for Binge Eating
Icahn School of Medicine at Mount Sinai
Binge Eating Disorder
Glutathione vs. Curcumin Clinical Trial
South Florida Veterans Affairs Foundation for Research and Education
Gulf War Syndrome
Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation
Robert J. Porte
Liver Failure · End Stage Liver Disease · Biliary Tract Diseases
Oral Glutathione Supplementation in Older Healthy Adults and Its Effect on the Number of Healthy Days Experienced During Four Months of Supplementation Compared to Placebo
University of Florida
Improvement in Immune Cell Function in Elderly Humans
GSH Supplementation on Cold/Flu Symptoms in Older Healthy Adults
University of Florida
Improvement in Immune Cell Function in Elderly Humans
Phase IIb Study of Intranasal Glutathione in Parkinson's Disease
Bastyr University
Parkinson's Disease
CNS Uptake of Intranasal Glutathione
University of Washington
Parkinson's Disease
Vitamin B-6 and Glutathione on Inflammation, Homocysteine, Oxidative Stress and Antioxidant Capacities
Taichung Veterans General Hospital
Liver Cirrhosis · Liver Cancer
Oral Liposomal Glutathione Supplementation in Healthy Subjects
Milton S. Hershey Medical Center
Healthy
Safety and Immunogenicity Study of Na-GST-1 With or Without CpG
Baylor College of Medicine
Hookworm Infection · Hookworm Disease
Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL)
Universitaire Ziekenhuizen KU Leuven
Reperfusion Injury
Biological Evaluation of Dietary Supplement Liposomal Glutathione
University of Maryland, Baltimore
Schizophrenia
Sublingual L-GSH Supplementation in Male Subjects With Smoking Habit and/or Hypertension
Niguarda Hospital
Health Subjects With Cardiovascular Risk Factors
Safety, Pharmacokinetics and Pharmacodynamics Study With 2B3-201 in Healthy Subjects and Multiple Sclerosis(MS) Patients
BBB-Therapeutics B.V.
Healthy Volunteers · Multiple Sclerosis
Clinical and Pharmacological Study With 2B3-101 in Patients With Breast Cancer and Leptomeningeal Metastases
The Netherlands Cancer Institute
Meningeal Carcinomatosis
Smartphone Technology and CBT-GSH in Binge Eaters
Icahn School of Medicine at Mount Sinai
Binge Eating Disorder · Bulimia Nervosa
Intranasal Glutathione in Parkinson's Disease
Bastyr University
Parkinson's Disease (PD)
Glutathione and Health With Post-Polio Syndrome
University of Michigan
Post-polio Syndrome · Physical Activity · Depression · Pain
An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.
BBB-Therapeutics B.V.
Brain Metastases · Lung Cancer · Breast Cancer · Melanoma
Effects of Glutathione (an Antioxidant) and N-Acetylcysteine on Inflammation
Stanford University
Obesity · Hyperlipidemia · Insulin Resistance · Hypertension
A Study Evaluating the Efficacy of Glucocorticoids in Patients With Pre-ACLF-HBV
Third Military Medical University
Liver Failure · Hepatitis B
Supplementation of Oral Reduced Glutathione in Pediatric Cystic Fibrosis Patients
Clark Bishop
Cystic Fibrosis
The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels
Charles Drew University of Medicine and Science
Oxidative Stress
Inhaled Glutathione (GSH) Versus Placebo in Cystic Fibrosis
Serafino A. Marsico
Cystic Fibrosis
Study of Oral Darinaparsin in Patients With Advanced Solid Tumors
Alaunos Therapeutics
Advanced Solid Tumors
Polymorphism of Oxidative Stress Genes in the Pathogenesis and Antioxidant Prevention of Contrast Induced Nephropathy
Huashan Hospital
Nephropathy · Oxidative Stress
Oral Glutathione Supplementation on the Levels of Blood Glutathione
Milton S. Hershey Medical Center
Healthy Adults
Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer
Alliance for Clinical Trials in Oncology
Chemotherapeutic Agent Toxicity · Neuropathy · Neurotoxicity Syndrome · Pain
Study of Glutathione, Vitamin C and Cysteine in Children With Autism and Severe Behavior Problems
University of Louisville
Autism · Severe Behavior Disorder
Role of Oral Glutathione in Skin Whitening
Chulalongkorn University
Skin Whitening
Efficacy and Safety Study of Inhaled Glutathione in Cystic Fibrosis Patients
Mukoviszidose Institut gGmbH
Cystic Fibrosis
NOV-002, Doxorubicin, Cyclophosphamide, and Docetaxel in Women With Newly Diagnosed Stage II or IIIC Breast Cancer
University of Miami
Breast Cancer
Efficacy of NOV-002 in Combination With Carboplatin in Chemotherapy-resistant Ovarian Cancer
Cellectar Biosciences, Inc.
Ovarian Cancer
Weekly Dosing of an Integrative Chemotherapy Combination to Treat Advanced Pancreatic Cancer
Seattle Cancer Treatment and Wellness Center
Adenocarincoma of Pancreas · Stage III Pancreatic Cancer · Stage IVA Pancreatic Cancer · Stage IVB Pancreatic Cancer
Effect of Glutathione on Blood Alcohol and Hangover Symptoms
Piyavate Hospital
Alcohol Drinking
Effects of Orotic Acid Derivatives With or Without Glutathione on Allergic Rhinitis
University of Mississippi Medical Center
Seasonal Allergic Rhinitis
RayGel-An Alternative for Skin Care During External Beam Radiation
Nathalie Johnson
Breast Cancer
N-acetylcysteine in Liver Transplantation
Ibtesam Hilmi
End Stage Liver Failure
Glutathione (GSH) In The Treatment of Parkinson's Disease
University of South Florida
Parkinson's Disease
Effectiveness of Binge Eating Disorder Treatments
Stanford University
Eating Disorders
Glutathione and Its Precursors in HIV-Infected Patients
UPECLIN HC FM Botucatu Unesp
HIV Infection
Clinical Trial on the Therapy of the Reperfusion Injury during an Acute Myocardial Infarction
German Research Foundation (Deutsche Forschungsgemeinschaft) (DFG)
Acute myocardial infarction
Sources: ClinicalTrials.gov, the EU Clinical Trials Information System and ISRCTN, deduplicated so a study registered in more than one registry is counted once. A study is listed when Glutathione is named as an intervention. A registered trial is a plan, not a result — registration says nothing about whether the peptide worked.