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Peptide Database

Goals
Fat LossMuscle BuildingInjury HealingAnti-AgingCognitive EnhancementSleep OptimizationImmune SupportGut HealingSkin RejuvenationSexual Health
Peptides
5-Amino-1MQ
Weight Management
Abarelix
Hormone Support
Acetyl Hexapeptide-3 (Argireline)
Cosmetic
Adipotide
Weight Management
Adrenomedullin
Healing & Recovery
Alexamorelin
Growth Hormone
Angiotensin (1-7)
Healing & Recovery
AOD-9604
Weight Management
Apelin-13
Healing & Recovery
ARA-290 (Cibinetide)
Healing & Recovery
Bestatin (Ubenimex)
Immune
BPC-157
Healing & Recovery
Buserelin
Hormone Support
Cagrilintide
Weight Management
CagriSema
Weight Management
Capromorelin
Growth Hormone
Cartalax
Anti-Aging
Cathelicidin (hCAP-18 / Synthetic Derivatives)
Immune
Cerebrolysin
Cognitive
Cerluten
Cognitive
Cetrorelix
Hormone Support
Chonluten
Immune
CJC-1295 (No DAC)
Growth Hormone
CJC-1295 with DAC
Growth Hormone
Cortexin
Cognitive
Crystagen
Immune
Daptomycin
Immune
Defensin (HBD-2)
Immune
Defensin (HBD-3)
Immune
Degarelix
Hormone Support
Dihexa
Cognitive
DSIP (Delta Sleep-Inducing Peptide)
Sleep & Recovery
Dulaglutide
Weight Management
Enalapril
Healing & Recovery
Epithalon
Anti-Aging
Exenatide
Weight Management
Fertirelin
Hormone Support
FOXO4-DRI
Anti-Aging
Ganirelix
Hormone Support
GHK-Cu (Copper Peptide)
Cosmetic
GHRH (1-29)
Growth Hormone
GHRP-2
Growth Hormone
GHRP-6 (Growth Hormone Releasing Peptide-6)
Growth Hormone
Glutathione
Anti-Aging
Gonadorelin (GnRH)
Hormone Support
Gramicidin
Immune
Hexarelin
Growth Hormone
Human Chorionic Gonadotropin (HCG)
Hormone Support
Human Growth Hormone (HGH)
Growth Hormone
IGF-1 LR3
Growth Hormone
Immunoxel (Dzherelo)
Immune
Imunofan
Immune
Intermedin (Adrenomedullin-2)
Healing & Recovery
Ipamorelin
Growth Hormone
Kisspeptin-10
Sexual Health
KPV (Alpha-MSH Fragment)
Healing & Recovery
Lactoferricin B
Immune
Larazotide
Healing & Recovery
Lentinan
Immune
Leuphasyl
Cosmetic
Leuprolide
Hormone Support
Liraglutide
Weight Management
Livagen
Anti-Aging
Lixisenatide
Weight Management
LL-37
Immune
Macimorelin
Growth Hormone
Magainin-2
Immune
Mazdutide
Weight Management
Melanotan-2
Cosmetic
MK-677 (Ibutamoren)
Growth Hormone
MOTS-c
Metabolic
Myristoyl Pentapeptide-17
Cosmetic
N-Acetyl Selank
Cognitive
N-Acetyl Semax Amidate
Cognitive
NAD+
Mitochondrial
Nafarelin
Hormone Support
Natriuretic Peptide (ANP)
Healing & Recovery
Nesiritide (BNP)
Healing & Recovery
Nisin
Immune
Noopept (Omberacetam)
Cognitive
Orforglipron
Weight Management
Ovagen
Anti-Aging
Oxytocin Acetate
Hormone Support
P21 (P021)
Cognitive
PACAP-38
Healing & Recovery
Palmitoyl Oligopeptide
Cosmetic
Palmitoyl Pentapeptide-4 (Matrixyl)
Cosmetic
Palmitoyl Tetrapeptide-7
Cosmetic
Palmitoyl Tripeptide-1
Cosmetic
Pancragen
Metabolic
PEG-MGF
Healing & Recovery
Pemvidutide
Weight Management
Pentadecapeptide (BPC Analog)
Healing & Recovery
Pidotimod
Immune
Pinealon
Cognitive
PNC-27
Immune
Polymyxin B
Immune
Pralmorelin (GHRP-2)
Growth Hormone
Pramlintide
Weight Management
Prostamax
Hormone Support
PT-141 (Bremelanotide)
Sexual Health
Relaxin-2 (Serelaxin)
Healing & Recovery
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Setmelanotide
Weight Management
SLU-PP-332
Metabolic
SM-130686
Growth Hormone
Snap-8
Cosmetic
SS-31 (Elamipretide)
Mitochondrial
Substance P Antagonists
Healing & Recovery
Survodutide
Weight Management
SYN-AKE
Cosmetic
Tabimorelin
Growth Hormone
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Testagen
Hormone Support
Thymalin
Immune
Thymopentin (TP-5)
Immune
Thymopoietin
Immune
Thymosin Alpha-1
Immune
Thymosin Beta-4
Healing & Recovery
Thymulin (FTS)
Immune
Thymulin Analog (PAT)
Healing & Recovery
Tirzepatide
Weight Management
Tripeptide-29
Cosmetic
Triptorelin
Hormone Support
Ularitide
Healing & Recovery
Urocortin
Healing & Recovery
Ventfort
Anti-Aging
Vesilute
Hormone Support
Vilon
Immune
VIP (Vasoactive Intestinal Peptide)
Healing & Recovery
Xenin-25
Metabolic
Ziconotide (Prialt)
Healing & Recovery
Total Peptides: 137
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Condition Spotlight

Systemic Lupus
Erythematosus

Systemic Lupus Erythematosus is an autoimmune disease where your immune system literally attacks your own body - your joints, skin, kidneys, heart, and lungs. It predominantly affects women of childbearing age, often causing unpredictable flares that can be debilitating and dangerous.

Written by Michael Carroll — Owner, Director of Research · Reviewed by the Peptide Initiative Research Team · Editorial standards

The Problem

Your Immune System Has Gone
Rogue Against You

Systemic Inflammation

Widespread inflammation affecting multiple organ systems

Autoantibodies

Your body producing antibodies that attack itself

Tissue Damage

Progressive damage to joints, kidneys, skin, and organs

Understanding the Immune Cascade

When Your Immune System Mistakenly Attacks Itself

Systemic Lupus Erythematosus is a complex autoimmune disease in which your immune system loses its ability to distinguish between self and non-self. Instead of protecting you from harmful invaders, your immune cells produce antinuclear antibodies (ANAs) and other autoantibodies that attack your own cells and tissues. This triggers a cascade of inflammation throughout your body. Your body deposits immune complexes (antibody-antigen pairs) in your joints, kidneys, skin, and other organs, causing:joint inflammation and arthritis, kidney inflammation (lupus nephritis), skin rashes and photosensitivity, heart and lung inflammation, blood clotting abnormalities. The damage is compounded because once these autoimmune responses begin, they create a vicious cycle: damaged tissues release more self-antigens, which trigger more antibody production, creating more inflammation and more tissue damage.

"Your immune system, designed to protect you, has been reprogrammed to attack itself."

Peptide immunomodulators like Lupuzor and thymosin-based peptides offer a way to recalibrate your immune system - to help restore immune tolerance and reduce the autoimmune attack. Rather than broad immunosuppression, these peptides work to restore balance.

The Solutions

3 Peptides
3 Angles of Attack

Lupus Research Institute (Phase III Clinical Trials)

Lupuzor

Forigerimod - The Immune Recalibrator

A synthetic peptide that targets and restores balance to B cells, reducing autoantibody production directly at the source.

Role

Reprogramming a rogue military unit back to the correct orders

Learn more

1970s (thymus extract isolation)

Thymosin Alpha-1

The Immune Balancer

A naturally occurring thymic peptide that restores immune tolerance and reduces autoreactive cell activity.

Role

Retraining a corrupted army officer to recognize enemies vs citizens correctly

Various (BPC-157: 1990s, TB-500: 1980s-1990s)

Anti-Inflammatory Peptides

The Inflammation Suppressors

A class of peptides including BPC-157, TB-500 (Thymosin Beta-4), and others designed to reduce systemic inflammation and support tissue repair.

Role

Turning down the volume on a fire alarm that's constantly blaring

Learn more

The Strategy

How They Work Together
Together

PeptidePrimary RoleAnalogy
Lupuzor

Forigerimod - The Immune Recalibrator

Reprogramming a rogue military unit back to the correct orders

Thymosin Alpha-1

The Immune Balancer

Retraining a corrupted army officer to recognize enemies vs citizens correctly

Anti-Inflammatory Peptides

The Inflammation Suppressors

Turning down the volume on a fire alarm that's constantly blaring

3 Angles of Attack

Immune Recalibration

Lupuzor directly eliminates autoreactive B cells; Thymosin Alpha-1 restores regulatory T cells

Inflammation Reduction

Anti-inflammatory peptides reduce the cascading inflammatory response from autoimmune activation

Tissue Support

Anti-inflammatory peptides promote repair of already-damaged organs and tissues

Synergistic Effect

Together they address autoimmunity, inflammation, and tissue healing simultaneously

Important Considerations

Reality Check
What to Keep in Mind

Not a Replacement for Standard Care

Peptide immunomodulators complement but don't replace corticosteroids, NSAIDs, or hydroxychloroquine during initial treatment. Work with your rheumatologist.

Clinical Trials Show Promise

Lupuzor has completed Phase III trials with positive results. Thymosin Alpha-1 has preliminary evidence. More data continues to emerge.

Professional Guidance Essential

SLE is complex and varies significantly between patients. Work with a rheumatologist experienced in peptide therapy and SLE management.

Individual Response Varies

Some patients achieve remission, others low disease activity. Response depends on disease severity, duration, and individual immune factors.

This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before starting any new treatment.

Realistic Expectations

What to Expect: A Realistic Timeline

An honest breakdown based on research and clinical reports.

What's Happening Inside

Lupuzor begins binding to autoreactive B cells and triggering their elimination. Thymosin Alpha-1 starts recruiting regulatory T cells. Anti-inflammatory peptides begin reducing cytokine production, but systemic changes take longer to manifest.

What You Might Notice

  • Some patients report subtle improvement in energy or joint discomfort
  • Others notice nothing dramatic in this early window
  • Possible mild fatigue as immune system adjusts
  • No significant changes in lab markers yet

Watch For

Mild reactions possible at infusion site (Lupuzor) or injection sites (injected peptides). Generally well-tolerated.

Realistic Expectations

This is the 'loading' phase. Real benefits come later as autoantibody levels decrease.

Administration Guide

Dosing Protocols & Timing

General guidelines based on research literature and clinical reports. Work with a healthcare provider experienced in peptide therapy to customize for your situation.

Important: These are general guidelines. Don't self-prescribe based on internet articles. Work with a qualified healthcare provider.

Lupuzor

200 mcg intravenous infusion

Common Protocols

  • Phase III trial standard: 200 mcg IV infusion once monthly for 6 months
  • Each infusion administered over approximately 30 minutes
  • May be continued monthly if showing benefit, or extended to less frequent dosing based on clinical response

Timing Considerations

  • Administered in a clinical setting or qualified infusion center
  • Best administered on consistent monthly schedule
  • Some clinicians combine with other SLE treatments rather than replacing them entirely

Cycling

Clinical trial protocols: typically monthly infusions for 6 months, with assessment for continued benefit

Beyond Peptides

Lifestyle Strategies for Living Well

Peptides work best as part of a comprehensive approach. Click each category to explore evidence-based strategies.

At a Glance

Quick Reference Card

Peptide Overview

PeptideWhat It DoesTypical DoseTiming
Lupuzor
Forigerimod - The Immune Recalibrator200 mcg intravenous infusionAdministered in a clinical setting or qualified infusion center
Thymosin Alpha-1
The Immune Balancer1.6-1.6 mg twice weeklyCan be administered any time of day
Anti-Inflammatory Peptides
The Inflammation SuppressorsVaries by specific peptideCan be administered any time of day

Early Wins to Watch

  • Reduced joint pain and swelling
  • Fewer/less severe flares
  • Improved energy
  • Better sleep quality

Support Stack

Omega-3 fish oilVitamin DMagnesiumNACProbioticsQuercetinSelenium

Lifestyle Priorities

  • Stress management (critical)
  • Sleep consistency and duration
  • Anti-inflammatory nutrition
  • Sun protection (if photosensitive)
  • Consistent medical monitoring

Living with SLE is profoundly difficult. These peptides represent a genuine opportunity to recalibrate your immune system rather than just suppress it broadly. The difference between immune tolerance (the goal) and immunosuppression (the traditional approach) is significant - tolerance means your body can actually fight infections while attacking itself less.

Recovery is possible. Many patients achieve remission or low disease activity. Work closely with your rheumatologist, be patient with the timeline, and remember that controlling SLE now protects your long-term health.