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Peptide Database

Goals
Fat LossMuscle BuildingInjury HealingAnti-AgingCognitive EnhancementSleep OptimizationImmune SupportGut HealingSkin RejuvenationSexual Health
Peptides
Adipotide
Weight Management
AOD-9604
Weight Management
BPC-157
Healing & Recovery
Cagrilintide
Weight Management
CJC-1295
Growth Hormone
DSIP
Sleep & Recovery
Epithalon
Anti-Aging
GHK-Cu
Anti-Aging
GHRP-2
Growth Hormone
HCG
Hormone Support
Hexarelin
Growth Hormone
HGH
Growth Hormone
IGF-1 LR3
Growth Hormone
Kisspeptin
Hormone Support
Melanotan-2
Cosmetic
MOTS-C
Metabolic
NAD+
Anti-Aging
Oxytocin Acetate
Hormone Support
PEG-MGF
Recovery
PNC-27
Cancer Research
PT-141
Sexual Health
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Snap-8
Cosmetic
SS-31
Mitochondrial
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Thymosin Alpha-1
Immune
Tirzepatide
Weight Management
Total Peptides: 32
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Peptide Comparison

GHRP-6 (Growth Hormone Releasing Peptide-6)vsGHRP-2

A synthetic hexapeptide that signals your pituitary to release growth hormone through a unique pathway, with emerging evidence of heart-protective benefits.

A potent growth hormone releasing peptide that signals your pituitary gland to release more GH naturally—think of it as turning up the volume on your body's own growth hormone production.

Growth HormoneGrowth Hormone

At a Glance

Quick
comparison

Dose Range

GHRP-6 (Growth Hormone Releasing Peptide-6)

100–300 mcg

GHRP-2

100–300 mcg

Frequency

GHRP-6 (Growth Hormone Releasing Peptide-6)

Multiple times daily

GHRP-2

Multiple times daily

Administration

GHRP-6 (Growth Hormone Releasing Peptide-6)

Subcutaneous injection

GHRP-2

Subcutaneous injection

Cycle Length

GHRP-6 (Growth Hormone Releasing Peptide-6)

8-12 weeks

GHRP-2

8-12 weeks

Onset Speed

GHRP-6 (Growth Hormone Releasing Peptide-6)

Moderate (1-2 weeks)

GHRP-2

Rapid (hours to days)

Evidence Level

GHRP-6 (Growth Hormone Releasing Peptide-6)

Limited human trials

GHRP-2

Moderate human trials (Phase 1-2)

Efficacy

Benefit
ratings

GHRP-6 (Growth Hormone Releasing Peptide-6)
GHRP-2

Muscle Recovery and Growth

GHRP-6 (Growth Hormone Releasing Peptide-6)85%
GHRP-20%

Cellular Health and Protection

GHRP-6 (Growth Hormone Releasing Peptide-6)72%
GHRP-20%

Appetite and Nutrient Intake

GHRP-6 (Growth Hormone Releasing Peptide-6)88%
GHRP-20%

GH Release

GHRP-6 (Growth Hormone Releasing Peptide-6)0%
GHRP-295%

Recovery Speed

GHRP-6 (Growth Hormone Releasing Peptide-6)0%
GHRP-290%

Sleep Quality

GHRP-6 (Growth Hormone Releasing Peptide-6)0%
GHRP-288%

Technical Data

Compound
specifications

GHRP-6 (Growth Hormone Releasing Peptide-6)

Molecular Formula

C46H56N12O6

Molecular Weight

873.0 g/mol

Half-Life

~2.5 hours

Bioavailability

<1% oral, high subcutaneous

CAS Number

87616-84-0

GHRP-2

Molecular Formula

C45H55N9O6

Molecular Weight

817.97 g/mol

Half-Life

15-60 minutes

Bioavailability

High (subcutaneous)

CAS Number

158861-67-7

Protocols

Dosing
tiers

GHRP-6 (Growth Hormone Releasing Peptide-6)

starting

100 mcg per injection

1-2 times daily (morning and/or evening)

2-4 weeks

Begin with once-daily dosing to assess tolerance and individual response. Many users start with an evening injection to take advantage of natural nighttime GH pulses.

standard

150-200 mcg per injection

2-3 times daily (morning, afternoon, evening)

6-8 weeks

Most users find this range effective for sustained GH stimulation. Timing around workouts can maximize the anabolic response. Some space injections 4-6 hours apart.

advanced

250-300 mcg per injection

3+ times daily

8-12 weeks

Only for experienced users with good tolerance established. Higher frequency can lead to receptor desensitization, so cycling (e.g., 5 days on, 2 days off) may preserve effectiveness. Requires careful monitoring.

GHRP-2

starting

100 mcg

2-3 times daily

2-4 weeks

Begin here to assess tolerance and response. Best taken on an empty stomach, typically morning and before bed.

standard

150-200 mcg

2-3 times daily

8-12 weeks

The most commonly used dose range for consistent GH elevation. Inject on empty stomach for best absorption.

advanced

200-300 mcg

3 times daily

8-12 weeks

Maximum dose used by experienced users. Often combined with GHRH for synergistic effects. Monitor for increased side effects.

Applications

Best
suited for

GHRP-6 (Growth Hormone Releasing Peptide-6)

Athletes and Serious Trainers

If you're hitting the gym hard and want better recovery and muscle growth, GHRP-6 amplifies your body's natural GH response. This is particularly valuable during intense training phases when you want to maximize adaptation and minimize soreness. The appetite stimulation also helps you consume the calories you need to grow.

Those Exploring Novel Peptide Protocols

GHRP-6 offers a unique mechanism through the ghrelin receptor, making it valuable for users who want to explore diverse GH-stimulation pathways. It works distinctly from GHRH-based approaches and pairs well with other GH secretagogues for synergistic effects.

Longevity and Metabolic Health Enthusiasts

Growth hormone plays roles in metabolic health, body composition, and potentially aging markers. GHRP-6's emerging research on cellular protection and antioxidant activation makes it interesting for those interested in broader health optimization beyond just muscle growth.

GHRP-2

Natural Growth Hormone Optimization

GHRP-2 excels at stimulating your pituitary to release more of your own growth hormone. Unlike synthetic HGH, it works with your body's natural feedback systems, creating more physiological GH pulses that mimic what your body did when you were younger.

Recovery and Muscle Building

Athletes and fitness enthusiasts love GHRP-2 for its ability to speed up recovery between workouts. The elevated GH and IGF-1 levels help repair muscle tissue faster, reduce soreness, and support lean muscle growth—especially when combined with proper training and nutrition.

Deep Sleep Enhancement

One of the most noticeable effects users report is dramatically improved sleep quality. GHRP-2 taken before bed can enhance deep sleep phases, which is when your body does most of its repair work. Many users report waking up feeling more refreshed and recovered.

Anti-Aging and Vitality

As we age, natural GH production declines significantly. GHRP-2 helps restore more youthful GH levels, which can translate to better skin elasticity, improved energy, enhanced recovery capacity, and that overall feeling of vitality that tends to fade with age.

Appetite Stimulation

Unlike many peptides that suppress appetite, GHRP-2 is known for increasing hunger. This makes it ideal for hard-gainers trying to build muscle or anyone who struggles to eat enough calories. The appetite boost typically kicks in within 20-30 minutes of injection.

Safety Profile

Side
effects

GHRP-6 (Growth Hormone Releasing Peptide-6)

Common

  • Increased Appetite
  • Mild Joint or Muscle Discomfort
  • Water Retention or Mild Swelling

Uncommon

  • Sleep Disturbances
  • Mild Dizziness or Lightheadedness

Serious

  • Allergic Reaction

GHRP-2

Common

  • Increased appetite
  • Water retention
  • Tingling or numbness
  • Flushing

Uncommon

  • Elevated cortisol
  • Headaches

Serious

  • Blood sugar changes

Research Status

Safety
& evidence

GHRP-6 (Growth Hormone Releasing Peptide-6)

Evidence Level

Limited human trials

FDA Status

Research compound

Safety Overview

GHRP-6 has a relatively long research history dating back to 1981, with human studies demonstrating its ability to stimulate GH release. The good news is that animal safety studies show excellent tolerability at high doses, and the side effects reported are generally mild and reversible. However, it's not FDA-approved, so use is based on research evidence rather than pharmaceutical oversight. Always purchase from reputable sources and consider medical consultation, especially if you have existing health conditions.

Contraindications

  • xKnown allergy or sensitivity to any component of the peptide
  • xActive cancer or history of cancer without medical clearance
  • xSevere cardiovascular disease or uncontrolled hypertension
  • xAcute critical illness or sepsis

GHRP-2

Evidence Level

Moderate human trials (Phase 1-2)

FDA Status

Not FDA approved

Safety Overview

GHRP-2 has been studied in numerous human clinical trials and is generally well-tolerated at standard doses. The most common side effects are increased appetite and temporary water retention, which typically subside with continued use. It stimulates both GH and cortisol release, though cortisol elevation is usually mild and transient. Unlike synthetic HGH, GHRP-2 works within your body's natural feedback loops, reducing the risk of excessive GH levels.

Contraindications

  • xPregnancy or breastfeeding
  • xActive cancer or history of cancer
  • xPituitary tumors or disorders
  • xUncontrolled diabetes

Decision Guide

Which is
right for you?

Choose GHRP-6 (Growth Hormone Releasing Peptide-6) if...

  • Building lean muscle mass and improving body composition
  • Recovery from intense training programs and athletic performance
  • Supporting overall metabolic health and longevity markers
  • Exploring novel GH-stimulation pathways for those who respond well to peptide protocols

Choose GHRP-2 if...

  • Growth hormone optimization
  • Muscle building
  • Recovery enhancement
  • Anti-aging
GHRP-6 (Growth Hormone Releasing Peptide-6) vs GHRP-2 — Peptide Comparison | Peptide Initiative