Peptide Comparison
Pralmorelin (GHRP-2)vsCJC-1295 (No DAC)
A powerful hexapeptide that stimulates growth hormone release—used clinically in Japan for GH testing and studied for healing and anti-inflammatory effects.
A modified growth hormone-releasing hormone that boosts your body's natural GH pulses for better recovery, deeper sleep, and improved body composition.
At a Glance
Quick
comparison
Dose Range
Pralmorelin (GHRP-2)
100–300 mcg
CJC-1295 (No DAC)
100–300 mcg
Frequency
Pralmorelin (GHRP-2)
Once daily
CJC-1295 (No DAC)
Once daily
Administration
Pralmorelin (GHRP-2)
Subcutaneous injection
CJC-1295 (No DAC)
Subcutaneous injection
Cycle Length
Pralmorelin (GHRP-2)
4-6 weeks
CJC-1295 (No DAC)
8-12 weeks
Onset Speed
Pralmorelin (GHRP-2)
Rapid (hours to days)
CJC-1295 (No DAC)
Moderate (1-2 weeks)
Evidence Level
Pralmorelin (GHRP-2)
Limited human trials
CJC-1295 (No DAC)
Moderate human trials (Phase 1-2)
Efficacy
Benefit
ratings
Muscle & Performance Enhancement
Injury Recovery & Healing
Diagnostic Clinical Use
GH Stimulation
Sleep Quality
Recovery Support
Technical Data
Compound
specifications
Pralmorelin (GHRP-2)
Molecular Formula
C45H55N9O6
Molecular Weight
818.0 g/mol
Half-Life
15-60 minutes
Bioavailability
~100% (subcutaneous injection)
CAS Number
158861-67-7
CJC-1295 (No DAC)
Molecular Formula
C152H252N44O42
Molecular Weight
3367.9 g/mol
Half-Life
30 minutes to 2 hours
Bioavailability
~100% (subcutaneous)
CAS Number
863288-34-0
Protocols
Dosing
tiers
Pralmorelin (GHRP-2)
CJC-1295 (No DAC)
Applications
Best
suited for
Pralmorelin (GHRP-2)
Athletes and Fitness Enthusiasts
If you're serious about lean muscle gains and recovery, pralmorelin directly stimulates GH release—one of the body's most powerful anabolic hormones. Most athletes in research settings use 100-200 mcg for faster muscle repair and improved performance.
Individuals Recovering from Injury
Recent animal studies show GHRP-2 reduces inflammation and speeds tendon-bone healing. If you're dealing with sports injuries, rotator cuff issues, or fractures, this peptide's anti-inflammatory profile may accelerate recovery when combined with proper rehab.
Those Seeking Diagnostic GH Testing
If your doctor suspects growth hormone deficiency, pralmorelin is the gold-standard diagnostic tool in Japan and many countries. A single injection stimulates GH release, allowing physicians to assess your pituitary function safely and accurately.
Peptide Research Enthusiasts
Pralmorelin is one of the most extensively studied GHRPs worldwide. If you're exploring peptide protocols and understand research-grade products, this is a powerful tool for understanding how your GH axis responds to stimulation.
CJC-1295 (No DAC)
Natural Growth Hormone Optimization
Perfect for those wanting to boost their body's own GH production rather than using synthetic growth hormone. Mimics the natural pulsatile release pattern your pituitary uses.
Workout Recovery and Muscle Building
Athletes and fitness enthusiasts use it to accelerate recovery between training sessions, support lean muscle development, and reduce body fat over time.
Sleep Quality Enhancement
Because GH is naturally released during deep sleep, many users report dramatically improved sleep quality with more vivid dreams and feeling more refreshed upon waking.
Anti-Aging and Vitality
As GH levels decline with age, CJC-1295 helps restore more youthful hormone patterns, potentially improving skin quality, energy levels, and overall well-being.
Synergistic Peptide Stacking
Designed to work hand-in-hand with GHRPs like Ipamorelin. When combined, these peptides amplify each other's effects for significantly greater GH release than either alone.
Safety Profile
Side
effects
Pralmorelin (GHRP-2)
Common
- Facial flushing
- Transient headache
- Increased appetite
- Temporary dizziness or lightheadedness
Uncommon
- Carpal tunnel-like sensations
- Joint or muscle aches
- Sleep quality changes
Serious
- Severe allergic reaction (anaphylaxis)
CJC-1295 (No DAC)
Common
- Injection site reactions
- Flushing or warmth
- Water retention
- Increased appetite
Uncommon
- Tingling or numbness
- Headache
Serious
- Allergic reaction
Research Status
Safety
& evidence
Pralmorelin (GHRP-2)
Evidence Level
Limited human trials
FDA Status
Research compound
Safety Overview
Pralmorelin (GHRP-2) has been safely used in diagnostic settings in Japan for decades and is well-tolerated in most individuals when used at appropriate doses. The peptide is synthetic and chemically stable, with low immunogenicity risk. However, it is NOT FDA approved and should only be used under medical supervision or within research protocols. Long-term safety data in healthy humans is limited.
Contraindications
- xActive malignancy or unresolved cancer history
- xUncontrolled hypertension or severe cardiovascular disease
- xPregnancy or breastfeeding
- xAcute infection or sepsis
- xUncontrolled diabetes
CJC-1295 (No DAC)
Evidence Level
Moderate human trials (Phase 1-2)
FDA Status
Research compound
Safety Overview
CJC-1295 without DAC has been studied in Phase 1-2 human clinical trials with a favorable safety profile. The most common side effects are mild and include injection site reactions and temporary flushing. Because it stimulates natural GH release rather than providing exogenous GH, it maintains the body's feedback mechanisms.
Contraindications
- xActive cancer or history of cancer
- xPregnancy or breastfeeding
- xPituitary tumors or disorders
- xHypersensitivity to GHRH analogs
- xDiabetic retinopathy
Decision Guide
Which is
right for you?
Choose Pralmorelin (GHRP-2) if...
- Athletes seeking enhanced recovery and lean mass gains
- Individuals with suspected GH deficiency (diagnostic use)
- Recovery from tendon or bone injuries
- Those wanting to test GH axis responsiveness
Choose CJC-1295 (No DAC) if...
- Increasing natural growth hormone levels
- Building lean muscle mass
- Improving sleep quality
- Enhancing workout recovery