Peptide Comparison
GHRP-6 (Growth Hormone Releasing Peptide-6)vsCJC-1295 (No DAC)
A synthetic hexapeptide that signals your pituitary to release growth hormone through a unique pathway, with emerging evidence of heart-protective benefits.
A modified growth hormone-releasing hormone that boosts your body's natural GH pulses for better recovery, deeper sleep, and improved body composition.
At a Glance
Quick
comparison
Dose Range
GHRP-6 (Growth Hormone Releasing Peptide-6)
100–300 mcg
CJC-1295 (No DAC)
100–300 mcg
Frequency
GHRP-6 (Growth Hormone Releasing Peptide-6)
Multiple times daily
CJC-1295 (No DAC)
Once daily
Administration
GHRP-6 (Growth Hormone Releasing Peptide-6)
Subcutaneous injection
CJC-1295 (No DAC)
Subcutaneous injection
Cycle Length
GHRP-6 (Growth Hormone Releasing Peptide-6)
8-12 weeks
CJC-1295 (No DAC)
8-12 weeks
Onset Speed
GHRP-6 (Growth Hormone Releasing Peptide-6)
Moderate (1-2 weeks)
CJC-1295 (No DAC)
Moderate (1-2 weeks)
Evidence Level
GHRP-6 (Growth Hormone Releasing Peptide-6)
Limited human trials
CJC-1295 (No DAC)
Moderate human trials (Phase 1-2)
Efficacy
Benefit
ratings
Muscle Recovery and Growth
Cellular Health and Protection
Appetite and Nutrient Intake
GH Stimulation
Sleep Quality
Recovery Support
Technical Data
Compound
specifications
GHRP-6 (Growth Hormone Releasing Peptide-6)
Molecular Formula
C46H56N12O6
Molecular Weight
873.0 g/mol
Half-Life
~2.5 hours
Bioavailability
<1% oral, high subcutaneous
CAS Number
87616-84-0
CJC-1295 (No DAC)
Molecular Formula
C152H252N44O42
Molecular Weight
3367.9 g/mol
Half-Life
30 minutes to 2 hours
Bioavailability
~100% (subcutaneous)
CAS Number
863288-34-0
Protocols
Dosing
tiers
GHRP-6 (Growth Hormone Releasing Peptide-6)
CJC-1295 (No DAC)
Applications
Best
suited for
GHRP-6 (Growth Hormone Releasing Peptide-6)
Athletes and Serious Trainers
If you're hitting the gym hard and want better recovery and muscle growth, GHRP-6 amplifies your body's natural GH response. This is particularly valuable during intense training phases when you want to maximize adaptation and minimize soreness. The appetite stimulation also helps you consume the calories you need to grow.
Those Exploring Novel Peptide Protocols
GHRP-6 offers a unique mechanism through the ghrelin receptor, making it valuable for users who want to explore diverse GH-stimulation pathways. It works distinctly from GHRH-based approaches and pairs well with other GH secretagogues for synergistic effects.
Longevity and Metabolic Health Enthusiasts
Growth hormone plays roles in metabolic health, body composition, and potentially aging markers. GHRP-6's emerging research on cellular protection and antioxidant activation makes it interesting for those interested in broader health optimization beyond just muscle growth.
CJC-1295 (No DAC)
Natural Growth Hormone Optimization
Perfect for those wanting to boost their body's own GH production rather than using synthetic growth hormone. Mimics the natural pulsatile release pattern your pituitary uses.
Workout Recovery and Muscle Building
Athletes and fitness enthusiasts use it to accelerate recovery between training sessions, support lean muscle development, and reduce body fat over time.
Sleep Quality Enhancement
Because GH is naturally released during deep sleep, many users report dramatically improved sleep quality with more vivid dreams and feeling more refreshed upon waking.
Anti-Aging and Vitality
As GH levels decline with age, CJC-1295 helps restore more youthful hormone patterns, potentially improving skin quality, energy levels, and overall well-being.
Synergistic Peptide Stacking
Designed to work hand-in-hand with GHRPs like Ipamorelin. When combined, these peptides amplify each other's effects for significantly greater GH release than either alone.
Safety Profile
Side
effects
GHRP-6 (Growth Hormone Releasing Peptide-6)
Common
- Increased Appetite
- Mild Joint or Muscle Discomfort
- Water Retention or Mild Swelling
Uncommon
- Sleep Disturbances
- Mild Dizziness or Lightheadedness
Serious
- Allergic Reaction
CJC-1295 (No DAC)
Common
- Injection site reactions
- Flushing or warmth
- Water retention
- Increased appetite
Uncommon
- Tingling or numbness
- Headache
Serious
- Allergic reaction
Research Status
Safety
& evidence
GHRP-6 (Growth Hormone Releasing Peptide-6)
Evidence Level
Limited human trials
FDA Status
Research compound
Safety Overview
GHRP-6 has a relatively long research history dating back to 1981, with human studies demonstrating its ability to stimulate GH release. The good news is that animal safety studies show excellent tolerability at high doses, and the side effects reported are generally mild and reversible. However, it's not FDA-approved, so use is based on research evidence rather than pharmaceutical oversight. Always purchase from reputable sources and consider medical consultation, especially if you have existing health conditions.
Contraindications
- xKnown allergy or sensitivity to any component of the peptide
- xActive cancer or history of cancer without medical clearance
- xSevere cardiovascular disease or uncontrolled hypertension
- xAcute critical illness or sepsis
CJC-1295 (No DAC)
Evidence Level
Moderate human trials (Phase 1-2)
FDA Status
Research compound
Safety Overview
CJC-1295 without DAC has been studied in Phase 1-2 human clinical trials with a favorable safety profile. The most common side effects are mild and include injection site reactions and temporary flushing. Because it stimulates natural GH release rather than providing exogenous GH, it maintains the body's feedback mechanisms.
Contraindications
- xActive cancer or history of cancer
- xPregnancy or breastfeeding
- xPituitary tumors or disorders
- xHypersensitivity to GHRH analogs
- xDiabetic retinopathy
Decision Guide
Which is
right for you?
Choose GHRP-6 (Growth Hormone Releasing Peptide-6) if...
- Building lean muscle mass and improving body composition
- Recovery from intense training programs and athletic performance
- Supporting overall metabolic health and longevity markers
- Exploring novel GH-stimulation pathways for those who respond well to peptide protocols
Choose CJC-1295 (No DAC) if...
- Increasing natural growth hormone levels
- Building lean muscle mass
- Improving sleep quality
- Enhancing workout recovery