HCG
Human Chorionic Gonadotropin
Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone naturally produced during pregnancy that mimics luteinizing hormone (LH) activity. It's FDA-approved for fertility treatments and hypogonadism in men. HCG stimulates testosterone production in males and triggers ovulation in females, making it valuable for hormone support, fertility preservation during testosterone therapy, and reproductive treatments.
Complete Dosing Guide
How to Take HCG
For TRT Support/Maintenance
Low-Dose Protocol:
- 250-500 IU subcutaneously 2-3 times per week
- Maintains testicular function without interfering with TRT
- Preserves fertility during testosterone therapy
Standard Maintenance Dose:
- 500-1000 IU subcutaneously 2-3 times per week
- Balances testicular preservation with minimal side effects
- Most common protocol for men on TRT
How to Take It:
- Inject subcutaneously (under the skin) in the abdomen or thigh
- Rotate injection sites to prevent irritation
- Can be taken same day as testosterone injections
- Store reconstituted HCG in refrigerator
For Hypogonadism (Testosterone Replacement)
Starting Dose:
- 1000-1500 IU subcutaneously 3 times per week
- Monitor testosterone levels after 2-4 weeks
Standard Therapeutic Dose:
- 1500-3000 IU subcutaneously 3 times per week
- Adjust based on testosterone levels and symptom improvement
- Goal: testosterone levels 500-1000 ng/dL
High-Dose Protocol (for severe cases):
- 3000-4000 IU subcutaneously 3 times per week
- Used when lower doses don't achieve adequate testosterone levels
- Requires careful monitoring of estradiol levels
How to Take It:
- Maintain consistent injection schedule (e.g., Monday/Wednesday/Friday)
- Best absorbed when injected subcutaneously
- Can switch to intramuscular if skin reactions occur
For Post-Cycle Therapy (PCT)
Recovery Protocol:
- Week 1-2: 3000 IU every other day
- Week 3-4: 2000 IU every other day
- Week 5-6: 1000 IU every other day
- Often combined with SERMs (Clomid or Nolvadex) for optimal recovery
Alternative PCT Protocol:
- 2000-2500 IU 3 times per week for 3-4 weeks
- Begin 3-5 days after last steroid injection
- Continue until natural testosterone production resumes
For Fertility Enhancement
Male Fertility Protocol:
- 1500-3000 IU 3 times per week for minimum 3 months
- May combine with FSH if sperm production doesn't improve
- Continue until pregnancy achieved or sperm parameters normalize
Combined Fertility Protocol:
- HCG: 2000 IU 3 times per week
- Plus FSH: 75-150 IU every other day (if needed)
- Duration: 3-6 months minimum
For Cryptorchidism (Pediatric Use)
Standard Pediatric Protocol:
- 4000 units IM 3 times weekly for 3 weeks, OR
- 5000 units IM every other day for 4 injections, OR
- 500-1000 units IM 3 times weekly for 4-6 weeks
- Treatment typically between ages 4-9
Dosing Calculators
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Medical Disclaimer
HCG is FDA-approved for specific fertility indications and testosterone replacement therapy support. This information is for educational purposes only and should not replace consultation with healthcare providers. Use only under medical supervision with appropriate monitoring.