Peptide Comparison
Thymulin (FTS)vsThymalin
Zinc-dependent thymic hormone for immune restoration and T cell maturation
Russian thymic peptide complex that rejuvenates immune function and supports healthy aging
At a Glance
Quick
comparison
Dose Range
Thymulin (FTS)
100–500 mcg
Thymalin
5–10 mg
Frequency
Thymulin (FTS)
Once daily
Thymalin
Once daily
Administration
Thymulin (FTS)
Subcutaneous injection
Thymalin
Intramuscular injection
Cycle Length
Thymulin (FTS)
4-6 weeks
Thymalin
4-6 weeks
Onset Speed
Thymulin (FTS)
Moderate (1-2 weeks)
Thymalin
Moderate (1-2 weeks)
Evidence Level
Thymulin (FTS)
Limited human trials
Thymalin
Limited human trials
Efficacy
Benefit
ratings
Immune Restoration
Anti-Inflammatory
Age-Related Immune Decline
Longevity Support
Disease Prevention
Technical Data
Compound
specifications
Thymulin (FTS)
Molecular Formula
C33H54N12O15
Molecular Weight
858.9 g/mol
Half-Life
Approximately 2 hours
Bioavailability
Low oral bioavailability (injected administration required)
CAS Number
63958-90-7
Thymalin
Molecular Formula
Complex mixture; active dipeptide EW: C16H19N3O5
Molecular Weight
Polypeptide complex; components 250-1000 Da; active dipeptide EW ~321 Da
Half-Life
Not precisely characterized for complex; immune effects persist weeks post-administration
Bioavailability
High via intramuscular or subcutaneous injection
CAS Number
63958-90-7
Protocols
Dosing
tiers
Thymulin (FTS)
Thymalin
Applications
Best
suited for
Thymulin (FTS)
Age-Related Immune Decline
Thymulin levels naturally drop significantly in elderly populations. Supplementation can restore T cell maturation and immune responsiveness in aging. Research shows thymulin can reverse age-related thymic involution and restore helper/suppressor T cell balance.
Recovery from Severe Malnutrition
In severely malnourished individuals, the thymus shrinks and T cell development is impaired. In vitro studies show thymulin can restore T cell maturation even in those with thymic involution, making it useful in recovery protocols.
Chronic Inflammatory Conditions
Thymulin inhibits NF-κB activation and suppresses pro-inflammatory cytokines (IL-6, TNF-α, IL-8). Animal models show effectiveness in lung diseases, inflammatory pain, and neuroinflammation. Anti-inflammatory effects work through p38 MAPK suppression.
Thymalin
Aging Adults Seeking Immune Support
Thymalin is especially valuable for people over 55 whose thymus gland has naturally shrunk with age. By stimulating thymic function, it helps restore the immune training center that your body relies on to fight infections and stay healthy.
Longevity and Anti-Aging Protocols
Clinical studies tracking patients for 6-8 years showed Thymalin reduced mortality by 2.0-2.1-fold. Combined with Epitalon, the mortality reduction reached an impressive 4.1-fold, making this combination one of the most studied longevity peptide protocols.
Seasonal Illness Prevention
Research shows Thymalin cuts respiratory infection rates by 2.0-2.4-fold. A short 10-day course before cold and flu season can significantly boost your immune defenses for months afterward.
Safety Profile
Side
effects
Thymulin (FTS)
Common
- Local injection site reactions
- Mild fatigue or lethargy
- Transient headache
Uncommon
- Mild fever or chills
- Sleep disturbance or vivid dreams
- Appetite changes
- Transient lymph node swelling
Serious
- Severe allergic reaction
- Uncontrolled immune activation
Thymalin
Common
- No side effects in most patients
- Mild injection site reaction
Uncommon
- Transient low-grade fever
- Mild flu-like symptoms
- Temporary headache
Serious
- Severe allergic reaction
Research Status
Safety
& evidence
Thymulin (FTS)
Evidence Level
Limited human trials
FDA Status
Research compound
Safety Overview
Thymulin is a naturally occurring thymic hormone with favorable safety profile in research. No reported serious adverse events in animal models even at high doses. Limited human safety data but observed studies suggest good tolerability. Requires concurrent zinc supplementation for biological activity and additional safety assurance. Most concerns relate to immune overactivation in susceptible individuals, not direct peptide toxicity.
Contraindications
- xUncontrolled autoimmune disease
- xSevere zinc deficiency requiring IV repletion
- xThymic tumors or malignancies
- xPregnancy (limited safety data)
Thymalin
Evidence Level
Limited human trials
FDA Status
Research compound
Safety Overview
Thymalin has an excellent safety profile based on over 40 years of clinical use in Russia. Most patients experience zero side effects, and the peptide complex has been described as 'practically non-toxic' in research literature. It has been used safely in thousands of patients, including elderly populations over extended periods.
Contraindications
- xActive thymic tumors or malignancies
- xKnown hypersensitivity to animal-derived peptide products
- xPregnancy and breastfeeding (insufficient safety data)
- xSevere uncontrolled autoimmune disease without medical supervision
Decision Guide
Which is
right for you?
Choose Thymulin (FTS) if...
- Immune system restoration
- T cell maturation in immunocompromised states
- Age-related immune decline
- Chronic inflammatory conditions
Choose Thymalin if...
- Immune system restoration in aging adults
- Longevity and healthy aging support
- Reducing infection frequency and severity
- Multi-system health optimization