Immune Protocol
Thymosin Alpha-1Complete Dosing & Administration Guide
Your immune system's master trainer—a naturally occurring thymus peptide that wakes up tired immune cells, helps your body fight infections, and keeps your defenses sharp as you age.
Dose Range
1.6-3.2mg
Frequency
Twice weekly
Route
Subcutaneous injection
Cycle Length
8-12 weeks
Dosing
How much
do I take?
Starting Dose
1.6 mg
This is the standard clinical dose used in most research trials. Start here to assess your tolerance and response. The 1.6 mg dose (sometimes listed as 900 mcg/m2) has decades of safety data behind it.
Standard Dose
1.6 mg
The most common protocol used in clinical trials for hepatitis and cancer support. Inject on consistent days (like Monday/Thursday) for best results. This duration allows meaningful immune enhancement.
Advanced Dose
1.6 mg daily for 7 days, then twice weekly
Used in some severe infection and critical care protocols. The daily loading phase rapidly boots immune function, followed by maintenance. Only under medical supervision for serious conditions.
Timing
Best time to take
Morning or early afternoon injections work well for most people. Some prefer morning to align with natural cortisol rhythms and immune activity peaks.
With food?
Can be taken regardless of food. Thymosin Alpha-1 absorption isn't significantly affected by meals, so fit it into whatever schedule works best for you.
If stacking
If using with other peptides like BPC-157, inject at separate sites. Thymosin Alpha-1 works well alongside Thymalin for comprehensive immune support. Space injections at least a few hours apart when stacking.
Adjusting Your Dose
Increase if
- +You've tolerated the starting protocol well for 4+ weeks
- +Your healthcare provider recommends intensification for specific conditions
- +Blood work shows continued immune markers that could benefit from support
Decrease if
- -You experience persistent flu-like symptoms beyond the first week
- -Injection site reactions don't improve with site rotation
- -You develop signs of immune overstimulation (discuss with doctor)
- -Any autoimmune symptoms emerge or worsen
Signs of right dose
- ✓Fewer colds and infections over time
- ✓Faster recovery when you do get sick
- ✓Stable energy levels
- ✓Improved lab markers if tracking immune function
Dosing Calculator
Calculate Your Exact Dose
Step 1: Peptide Weight
Find the weight printed on your peptide vial label
Look here!
The peptide weight is printed on the label
Look here!
The weight is on the label
Administration
How do I
use it?
Reconstitution
What you need
- •Bacteriostatic water (BAC water)—the preservative keeps it safe for multiple doses
- •Insulin syringes (29-31 gauge) for precise dosing
- •Alcohol swabs for cleaning vial tops and injection sites
- •Your Thymosin Alpha-1 powder vial
Injection
Route
Subcutaneous injection (just under the skin)—this is how it was used in all major clinical trials and provides reliable absorption
Best sites
- •Abdominal area (2 inches away from navel)
- •Front or outer thigh
- •Back of upper arm
Technique
- 1.Wash hands thoroughly with soap and water
- 2.Clean the injection site with an alcohol swab and let it dry completely
- 3.Pinch about an inch of skin to create a small fold
- 4.Insert needle at 45-90 degree angle (45 if lean, 90 if more tissue)
- 5.Inject slowly and steadily over several seconds
- 6.Release the pinch, wait a moment, then withdraw needle
- 7.Apply light pressure if needed—don't rub the area
Storage
Signs of degradation
Sample Daily Schedule
Safety
Is it
safe?
Safety Profile
Thymosin Alpha-1 has one of the most extensive safety records of any peptide, with decades of clinical use across multiple countries. Studies consistently report minimal side effects—mostly limited to mild injection site reactions. The 2-hour half-life means it doesn't accumulate in your system. It's been used safely in thousands of patients with hepatitis, cancer, and other serious conditions.
Safety data comes from numerous Phase I-III clinical trials and post-marketing surveillance in countries where it's approved (China, Russia, and 30+ other nations). The FDA has granted orphan drug status for hepatocellular carcinoma and approved it for certain uses. Most serious adverse events in studies were related to underlying conditions, not the peptide itself.
Common Side Effects
Experienced by some users
Injection site reactions
Redness, mild swelling, or discomfort where you injected is the most frequently reported effect. It's your skin's normal response to the injection process.
Management: Rotate injection sites with each dose. Ice the area briefly if uncomfortable. These reactions typically resolve within 24-48 hours.
Mild fatigue
Some users feel a bit tired after their injection, especially in the first few doses. Your immune system is activating and that takes energy.
Management: Time your injections for when you can rest if needed. Most people find this improves after the first week as their body adjusts.
Flu-like symptoms
Mild muscle aches, low-grade warmth, or general 'blah' feeling in the first few doses. This is actually a sign your immune system is responding.
Management: Stay hydrated and rest. These symptoms usually fade quickly and don't return with continued dosing. If severe or persistent, reduce frequency.
Less Common
- •Mild fever
- •Lymph node awareness
These typically resolve with continued use or dose adjustment.
Stop and Seek Help If
- ×Any signs of allergic reaction—stop immediately and seek medical help
- ×Worsening of any autoimmune symptoms you may have
- ×Persistent fever above 101°F that doesn't resolve
- ×Severe or spreading injection site reactions
- ×Any new symptoms that concern you or feel abnormal
- ×Completion of your prescribed treatment cycle
Thymosin Alpha-1 is approved for specific uses in some countries but remains a research compound for other applications. Always work with a qualified healthcare provider when using any peptide therapy. This information is educational—not medical advice for your specific situation.
Interactions
With other peptides
- ✓Excellent pairing—both support thymus function through complementary mechanisms. Often used together in immune protocols.
- ✓Safe combination. BPC-157 focuses on healing while Thymosin Alpha-1 handles immune function—different targets, no conflict.
- ✓Can be combined for comprehensive aging support. Epithalon targets telomeres while Thymosin Alpha-1 supports immune aging.
- ✓Same family, different functions. TB-500 is for tissue repair; TA-1 is for immune function. Can be used together safely.
With medications
- !Immunosuppressants (cyclosporine, tacrolimus) - CONTRAINDICATED. Thymosin Alpha-1 stimulates immune function, directly opposing these medications. Could trigger transplant rejection.
- !Corticosteroids (prednisone) - May reduce Thymosin Alpha-1 effectiveness. If you need steroids, timing separation may help. Discuss with your doctor.
- ✓Interferon-alpha - Actually studied together extensively for hepatitis. The combination shows enhanced effectiveness in clinical trials.
- ✓Chemotherapy drugs - Research supports using Thymosin Alpha-1 alongside chemo to maintain immune function. Should be coordinated with oncologist.
With supplements
- ✓Vitamin D - Excellent combination. Vitamin D also supports immune function and may enhance Thymosin Alpha-1 effects.
- ✓Zinc - Safe and complementary. Zinc is essential for immune function and supports T-cell development.
- ✓Glutathione - Good pairing for overall immune and antioxidant support. No known interactions.
- ✓Echinacea - Both stimulate immunity. While likely safe, watch for signs of overstimulation if using together long-term.
Want the Full Picture?
View the complete Thymosin Alpha-1 research profile including mechanism of action, clinical studies, effectiveness timeline, and FAQ.
View Full Thymosin Alpha-1 Profile