Immune Protocol
ChonlutenComplete Dosing & Administration Guide
Bronchopulmonary tripeptide bioregulator (Glu-Asp-Gly) that restores respiratory epithelial function through DNA minor groove binding at ATTTC sequences, induces TNF tolerance in alveolar macrophages reducing inflammatory cytokines by up to 6-fold, and normalizes bronchial mucosa differentiation markers in aging lung tissue
Dose Range
5-10mg
Frequency
Once daily
Route
Sublingual (enteric-coated capsules)
Cycle Length
12+ weeks
Dosing
How much
do I take?
Starting Dose
1-2 capsules (5 mg each) sublingually once daily
Begin with the conservative oral protocol using enteric-coated capsules. Take on an empty stomach 15-30 minutes before meals for optimal absorption. The EDG tripeptide is designed for oral bioavailability through peptide transporters. Effects are gradual — bronchopulmonary gene expression changes build over the treatment course. Monitor respiratory function and note any changes in breathing comfort.
Standard Dose
5-10 mg subcutaneously or 2 capsules orally once daily
Standard Khavinson bioregulator protocol for bronchopulmonary support. Administer once daily for 10-20 consecutive days. Repeat courses every 3-6 months for sustained respiratory benefits. Can be combined with Vladonix for comprehensive immune-respiratory support or Epithalon for systemic geroprotection. The epigenetic changes initiated during treatment persist beyond the active course.
Advanced Dose
10 mg subcutaneously once daily
Extended protocol for significant respiratory compromise or advanced geroprotective programs. Used in clinical studies as part of comprehensive multi-peptide bioregulator therapy for elderly patients. Often combined with Vladonix (thymic), Epithalon (pineal), Vilon (immune), and Cerluten (brain) for whole-body bioregulation. Repeat courses every 3-6 months. Medical supervision recommended.
Timing
Best time to take
Take Chonluten at the same time each day for consistent blood levels. Morning dosing with breakfast is often preferred, but follow your healthcare provider's specific instructions.
With food?
Chonluten can typically be taken with or without food. Taking it with a light meal may help reduce any GI discomfort. Avoid taking with grapefruit juice or high-fat meals unless specifically directed.
If stacking
Chonluten should be used as directed by your healthcare provider. If combining with other medications or supplements, discuss potential interactions with your provider. Avoid combining with compounds that have overlapping mechanisms unless specifically guided by a medical professional.
Adjusting Your Dose
Increase if
- +You've tolerated the current dose for the recommended period without significant side effects
- +Therapeutic goals haven't been met at the current dose level
- +Your healthcare provider recommends dose escalation based on your response
- +Lab work or clinical assessments support a higher dose
Decrease if
- -Side effects are bothersome or impacting daily life despite management strategies
- -You experience any signs of an adverse reaction
- -Lab results indicate the need for dose reduction
- -Your healthcare provider recommends a lower dose based on your response
Signs of right dose
- ✓Therapeutic goals being met with minimal side effects
- ✓Stable and consistent response to treatment
- ✓Lab values or clinical markers trending in the right direction
- ✓Good tolerance with manageable or absent side effects
Dosing Calculator
Calculate Your Exact Dose
Step 1: Peptide Weight
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Administration
How do I
use it?
Reconstitution
What you need
- •Chonluten in its prescribed form
- •Clean, dry storage container
- •Measuring device if applicable (oral syringe, measuring cup)
- •Calendar or reminder app for dosing schedule
Injection
Route
Chonluten is administered Sublingual (enteric-coated capsules)—no injection required
Best sites
- •Not applicable—this is not an injectable formulation
Technique
- 1.Follow the specific administration instructions for your Chonluten formulation
- 2.Take or apply as directed by your healthcare provider
- 3.Store properly between uses according to package instructions
Storage
Signs of degradation
Sample Daily Schedule
Safety
Is it
safe?
Safety Profile
Chonluten is a cartilage-derived peptide extract used primarily in Russian and Eastern European medicine that lacks FDA approval and rigorous clinical safety data. As a poorly defined mixture of collagen peptides and proteoglycans from cartilage tissue, standardization and batch consistency cannot be guaranteed. Potential risks include allergic reactions to connective tissue proteins, contamination from animal tissues, and unknown immunological effects from proteoglycan components. No formal safety assessments, animal toxicology studies by modern standards, or human Phase 1/2 trials exist. Long-term safety outcomes are completely unstudied.
Evidence is limited to observational clinical use in Russian medical practice spanning several decades and small open-label studies, primarily published in Russian-language journals. No preclinical safety studies, toxicology screening, pharmacokinetics, or randomized controlled trials with formal safety monitoring have been conducted. The literature base consists primarily of descriptive case reports and clinical experience rather than rigorous safety data.
Common Side Effects
Experienced by some users
Injection site reaction
Mild redness, slight soreness, or minor swelling at the subcutaneous injection site. Standard for injectable peptide bioregulators.
Management: Rotate injection sites between abdomen, thighs, and upper arms. Apply cold compress if needed. Resolves spontaneously within 24-48 hours.
Mild fatigue
Slight fatigue during initial days as bronchopulmonary immune function recalibrates and respiratory gene expression programs activate.
Management: Rest as needed. Usually resolves within 2-3 days. Ensure adequate sleep and hydration.
Transient respiratory changes
Mild increase in mucus production or slight changes in respiratory secretions as bronchial epithelial normalization occurs.
Management: Generally benign — indicates active epithelial remodeling. Stay hydrated. Should stabilize within several days.
Mild headache
Transient headache during the first few days of treatment, potentially related to immune activation and cytokine level adjustment.
Management: Ensure adequate hydration. Standard analgesics if needed. Usually self-limiting.
Less Common
- •Flu-like symptoms
These typically resolve with continued use or dose adjustment.
Stop and Seek Help If
- ×Severe or worsening side effects that don't improve with dose adjustment or supportive care
- ×Signs of an allergic reaction—rash, hives, swelling, or difficulty breathing
- ×Your healthcare provider recommends discontinuation based on your clinical response
- ×Development of any new medical condition that may be contraindicated with Chonluten
- ×Pregnancy or planning to become pregnant (unless specifically approved for use during pregnancy)
- ×Abnormal lab results or clinical markers that suggest adverse effects
Chonluten should only be started, adjusted, or discontinued under medical supervision. This information is for educational purposes only and does not replace professional medical advice. Never stop a prescribed treatment without consulting your healthcare provider first, as abrupt discontinuation may have consequences.
Interactions
With other peptides
- ✓May be used together under medical guidance.
- ✓May be used together under medical guidance.
- ✓May be used together under medical guidance.
With medications
- !Immunosuppressive medications (cyclosporine, tacrolimus) — Chonluten's immunomodulatory effects may counteract immunosuppression - Use with caution—discuss with your healthcare provider.
- !High-dose systemic corticosteroids — may interfere with Chonluten's bronchial epithelial differentiation mechanisms - Use with caution—discuss with your healthcare provider.
- !Other potent immunostimulants at high doses without medical supervision — risk of immune overactivation in pulmonary tissue - Use with caution—discuss with your healthcare provider.
With supplements
- ✓Multivitamins - Generally safe to take alongside Chonluten. Space doses apart if taking oral formulations to ensure optimal absorption.
- ✓Electrolyte supplements - Helpful if experiencing any GI side effects that could lead to dehydration. Safe to combine.
Want the Full Picture?
View the complete Chonluten research profile including mechanism of action, clinical studies, effectiveness timeline, and FAQ.
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