Understanding Central Sensitization
When Your Pain Amplifier Gets Stuck On
Your nervous system is supposed to process pain signals and then move on. With fibromyalgia, something goes wrong - the system gets hypersensitive, amplifying normal sensations into pain. Researchers call this central sensitization.
Think of it like the volume knob on your pain perception being turned up to maximum. A light touch feels like a burn. Normal pressure feels like injury. Even the thought of pain can trigger physical sensations.
The culprit? Multiple factors working together: Substance P (a neurotransmitter that carries pain signals) gets elevated 3-8 times higher than normal. Your brain's natural pain-suppressing chemicals become depleted. Neuroinflammation - inflammation of the nervous system itself - keeps everything hyperactivated. And social stress, trauma, or even infections can trigger the whole cascade.
"Your pain system is stuck in alarm mode, treating normal sensations as threats."
This is where peptide therapy offers a fundamentally different approach. Rather than just blocking pain signals, certain peptides can reset your nervous system's sensitivity, restore natural pain inhibition, and reduce neuroinflammation. They address the root malfunction instead of just turning down the volume.