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Peptide Database

Goals
Fat LossMuscle BuildingInjury HealingAnti-AgingCognitive EnhancementSleep OptimizationImmune SupportGut HealingSkin RejuvenationSexual Health
Peptides
5-Amino-1MQ
Weight Management
Abarelix
Hormone Support
Acetyl Hexapeptide-3 (Argireline)
Cosmetic
Adipotide
Weight Management
Adrenomedullin
Healing & Recovery
Alexamorelin
Growth Hormone
Angiotensin (1-7)
Healing & Recovery
AOD-9604
Weight Management
Apelin-13
Healing & Recovery
ARA-290 (Cibinetide)
Healing & Recovery
Bestatin (Ubenimex)
Immune
BPC-157
Healing & Recovery
Buserelin
Hormone Support
Cagrilintide
Weight Management
CagriSema
Weight Management
Capromorelin
Growth Hormone
Cartalax
Anti-Aging
Cathelicidin (hCAP-18 / Synthetic Derivatives)
Immune
Cerebrolysin
Cognitive
Cerluten
Cognitive
Cetrorelix
Hormone Support
Chonluten
Immune
CJC-1295 (No DAC)
Growth Hormone
CJC-1295 with DAC
Growth Hormone
Cortexin
Cognitive
Crystagen
Immune
Daptomycin
Immune
Defensin (HBD-2)
Immune
Defensin (HBD-3)
Immune
Degarelix
Hormone Support
Dihexa
Cognitive
DSIP (Delta Sleep-Inducing Peptide)
Sleep & Recovery
Dulaglutide
Weight Management
Enalapril
Healing & Recovery
Epithalon
Anti-Aging
Exenatide
Weight Management
Fertirelin
Hormone Support
FOXO4-DRI
Anti-Aging
Ganirelix
Hormone Support
GHK-Cu (Copper Peptide)
Cosmetic
GHRH (1-29)
Growth Hormone
GHRP-2
Growth Hormone
GHRP-6 (Growth Hormone Releasing Peptide-6)
Growth Hormone
Glutathione
Anti-Aging
Gonadorelin (GnRH)
Hormone Support
Gramicidin
Immune
Hexarelin
Growth Hormone
Human Chorionic Gonadotropin (HCG)
Hormone Support
Human Growth Hormone (HGH)
Growth Hormone
IGF-1 LR3
Growth Hormone
Immunoxel (Dzherelo)
Immune
Imunofan
Immune
Intermedin (Adrenomedullin-2)
Healing & Recovery
Ipamorelin
Growth Hormone
Kisspeptin-10
Sexual Health
KPV (Alpha-MSH Fragment)
Healing & Recovery
Lactoferricin B
Immune
Larazotide
Healing & Recovery
Lentinan
Immune
Leuphasyl
Cosmetic
Leuprolide
Hormone Support
Liraglutide
Weight Management
Livagen
Anti-Aging
Lixisenatide
Weight Management
LL-37
Immune
Macimorelin
Growth Hormone
Magainin-2
Immune
Mazdutide
Weight Management
Melanotan-2
Cosmetic
MK-677 (Ibutamoren)
Growth Hormone
MOTS-c
Metabolic
Myristoyl Pentapeptide-17
Cosmetic
N-Acetyl Selank
Cognitive
N-Acetyl Semax Amidate
Cognitive
NAD+
Mitochondrial
Nafarelin
Hormone Support
Natriuretic Peptide (ANP)
Healing & Recovery
Nesiritide (BNP)
Healing & Recovery
Nisin
Immune
Noopept (Omberacetam)
Cognitive
Orforglipron
Weight Management
Ovagen
Anti-Aging
Oxytocin Acetate
Hormone Support
P21 (P021)
Cognitive
PACAP-38
Healing & Recovery
Palmitoyl Oligopeptide
Cosmetic
Palmitoyl Pentapeptide-4 (Matrixyl)
Cosmetic
Palmitoyl Tetrapeptide-7
Cosmetic
Palmitoyl Tripeptide-1
Cosmetic
Pancragen
Metabolic
PEG-MGF
Healing & Recovery
Pemvidutide
Weight Management
Pentadecapeptide (BPC Analog)
Healing & Recovery
Pidotimod
Immune
Pinealon
Cognitive
PNC-27
Immune
Polymyxin B
Immune
Pralmorelin (GHRP-2)
Growth Hormone
Pramlintide
Weight Management
Prostamax
Hormone Support
PT-141 (Bremelanotide)
Sexual Health
Relaxin-2 (Serelaxin)
Healing & Recovery
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Setmelanotide
Weight Management
SLU-PP-332
Metabolic
SM-130686
Growth Hormone
Snap-8
Cosmetic
SS-31 (Elamipretide)
Mitochondrial
Substance P Antagonists
Healing & Recovery
Survodutide
Weight Management
SYN-AKE
Cosmetic
Tabimorelin
Growth Hormone
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Testagen
Hormone Support
Thymalin
Immune
Thymopentin (TP-5)
Immune
Thymopoietin
Immune
Thymosin Alpha-1
Immune
Thymosin Beta-4
Healing & Recovery
Thymulin (FTS)
Immune
Thymulin Analog (PAT)
Healing & Recovery
Tirzepatide
Weight Management
Tripeptide-29
Cosmetic
Triptorelin
Hormone Support
Ularitide
Healing & Recovery
Urocortin
Healing & Recovery
Ventfort
Anti-Aging
Vesilute
Hormone Support
Vilon
Immune
VIP (Vasoactive Intestinal Peptide)
Healing & Recovery
Xenin-25
Metabolic
Ziconotide (Prialt)
Healing & Recovery
Total Peptides: 137
Back to Home

Men's Health Spotlight

Erectile
Dysfunction

30 million American men deal with erectile dysfunction. It's not just about sex - it's about confidence, relationships, and your cardiovascular health. The good news? New peptide therapies are offering real solutions that work differently than traditional approaches.

Written by Michael Carroll — Owner, Director of Research · Reviewed by the Peptide Initiative Research Team · Editorial standards

The Problem

It Starts With Blood Flow
But It's More Complex Than That

Reduced Arousal

Difficulty initiating or maintaining sexual interest

Poor Erection Quality

Difficulty achieving or maintaining adequate firmness

Performance Anxiety

Worry that makes the problem worse

Understanding Erectile Dysfunction

Why It Happens (And Why Traditional Approaches Miss Half the Picture)

Erectile dysfunction is fundamentally a vascular and neurological problem. When you're aroused, specialized tissue in the penis called the corpus cavernosum fills with blood. This requires both good blood flow and the right neurological signals. But here's what most people miss: ED isn't just about blood vessels. It also involves:

Dopamine and sexual motivation - Your brain's reward system needs to be engaged
Melanocortin signaling - Specific brain pathways that directly trigger sexual arousal
Vascular function - Nitric oxide production in blood vessel lining
Hormonal balance - Testosterone, prolactin, and other key hormones

"ED is often an early warning sign of cardiovascular disease - fixing it might save your life."

Traditional treatments like Viagra work by enhancing blood flow, but they don't address motivation, arousal, or the underlying cardiovascular dysfunction. Peptide therapies attack this from multiple angles - directly stimulating arousal centers in the brain, improving vascular function, and supporting the neurological signals that make sex work.

The Solutions

3 Peptides
3 Angles of Attack

2019

Bremelanotide (PT-141)

The Arousal Peptide

FDA-approved peptide that activates melanocortin receptors in the brain, directly triggering sexual arousal in both men and women.

Role

Flipping the 'on switch' for sexual desire

Learn more

1999

Kisspeptin

The Sexual Axis Regulator

A naturally occurring peptide that regulates the hypothalamic-pituitary-gonadal axis, controlling testosterone production and sexual function.

Role

The master switch for reproductive hormones

1980s

Melanotan II

The Research Compound

A synthetic melanocortin analog in research phases that stimulates sexual arousal and erectile function similar to PT-141 but with additional effects.

Role

A more potent arousal activator with broader systemic effects

Learn more

The Strategy

How They Work Together
Together

PeptidePrimary RoleAnalogy
Bremelanotide (PT-141)

The Arousal Peptide

Flipping the 'on switch' for sexual desire

Kisspeptin

The Sexual Axis Regulator

The master switch for reproductive hormones

Melanotan II

The Research Compound

A more potent arousal activator with broader systemic effects

3 Angles of Attack

Central Arousal Stimulation

PT-141 and Melanotan II activate brain arousal centers, making you actually want sex

Vascular Enhancement

VIP relaxes penile smooth muscle and improves blood flow, supporting the physical mechanics

Hormonal Optimization

Kisspeptin naturally elevates testosterone, improving libido and sexual motivation

Comprehensive Sexual Function

Together they address desire, arousal, vascular function, and hormonal support simultaneously

Important Considerations

Reality Check
What to Keep in Mind

ED is Often Multifactorial

Rarely one single cause. Vascular, hormonal, neurological, and psychological factors usually all play a role. Address all of them.

Clinical Evidence Varies

PT-141/Bremelanotide is FDA-approved with solid evidence. Other peptides have promising research but are not all FDA-approved. Discuss with your provider.

Medical Supervision Recommended

ED can indicate serious cardiovascular disease. Get proper medical evaluation before starting peptide therapy.

Combination Often Superior

Individual peptides help, but combined approaches (peptides + cardiovascular optimization + lifestyle) create the best outcomes.

This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before starting any new treatment.

Realistic Expectations

What to Expect: A Realistic Timeline

An honest breakdown based on research and clinical reports.

Administration Guide

Dosing Protocols & Timing

General guidelines based on research literature and clinical reports. Work with a healthcare provider experienced in peptide therapy to customize for your situation.

Important: These are general guidelines. Don't self-prescribe based on internet articles. Work with a qualified healthcare provider.

Bremelanotide (PT-141)

1.75 mg per dose

Common Protocols

  • FDA-approved: 1.75 mg subcutaneous injection, 45 minutes before anticipated sexual activity
  • Can be used daily if desired, or occasional use as needed
  • Some providers use lower doses (0.5-1 mg) for testing tolerance

Timing Considerations

  • Inject 45 minutes before planned sexual activity
  • Take with or without food
  • Peak effects typically 30-60 minutes post-injection
  • Effects last 4-6 hours

Cycling

As-needed dosing before sexual activity (typically 45 minutes before)

Beyond Peptides

Lifestyle Strategies for Living Well

Peptides work best as part of a comprehensive approach. Click each category to explore evidence-based strategies.

At a Glance

Quick Reference Card

Peptide Overview

PeptideWhat It DoesTypical DoseTiming
Bremelanotide (PT-141)
The Arousal Peptide1.75 mg per doseInject 45 minutes before planned sexual activity
Kisspeptin
The Sexual Axis Regulator1-10 mcg per injection (highly variable, still in clinical trials)Timing protocols still being established in clinical research
Melanotan II
The Research Compound0.25-2 mg per doseCan be dosed any time, as it has long-lasting effects

Early Wins to Watch

  • PT-141 shows effects within first dose
  • Improved arousal and libido within days to weeks
  • Better erectile quality within 2-4 weeks
  • Increased confidence from successful sexual function

Support Stack

L-CitrullineL-ArginineGinsengZincVitamin D3Tribulus TerrestrisMagnesium

Lifestyle Priorities

  • Cardiovascular health and aerobic exercise
  • Sleep optimization
  • Stress management
  • Healthy diet (Mediterranean style optimal)
  • Open communication with partner

Erectile dysfunction is treatable. You don't have to accept it as inevitable. These peptides represent a real opportunity to restore sexual function and confidence. The best outcomes come from combining peptide therapy with cardiovascular health, hormonal optimization, and psychological work. Your sexual health is worth the effort.

Remember: this is about more than sex. It's about feeling like yourself again, confidence, connection, and recognizing that your body can still do amazing things. You've got this.