Peptide Comparison
SLU-PP-332vsMOTS-c
A groundbreaking exercise mimetic compound that tricks your body into thinking it's training for a marathon—boosting metabolism, burning fat, and building endurance without you ever having to hit the gym.
A remarkable 16-amino-acid peptide encoded by your mitochondrial DNA that acts as an 'exercise mimetic'—boosting metabolism, improving insulin sensitivity, and helping your cells adapt to metabolic stress just like a good workout would.
At a Glance
Quick
comparison
Dose Range
SLU-PP-332
250–1500 mcg
MOTS-c
5–15 mg
Frequency
SLU-PP-332
Once daily
MOTS-c
Once daily
Administration
SLU-PP-332
Oral
MOTS-c
Subcutaneous injection
Cycle Length
SLU-PP-332
8-12 weeks
MOTS-c
4-6 weeks
Onset Speed
SLU-PP-332
Moderate (1-2 weeks)
MOTS-c
Moderate (1-2 weeks)
Evidence Level
SLU-PP-332
Strong preclinical (extensive animal studies)
MOTS-c
Strong preclinical (extensive animal studies)
Efficacy
Benefit
ratings
Metabolic Enhancement
Exercise Mimetic
Fat Loss Support
Insulin Sensitivity
Mitochondrial Function
Technical Data
Compound
specifications
SLU-PP-332
Molecular Formula
C18H14N2O2
Molecular Weight
290.3 g/mol
Half-Life
Estimated 4-8 hours
Bioavailability
Moderate (oral); High (injection)
CAS Number
863971-53-5
MOTS-c
Molecular Formula
C101H152N28O22S2
Molecular Weight
2174.64 g/mol
Half-Life
Approximately 4-8 hours (estimated from preclinical data)
Bioavailability
High when injected subcutaneously
CAS Number
1627580-64-6
Protocols
Dosing
tiers
SLU-PP-332
MOTS-c
Applications
Best
suited for
SLU-PP-332
Metabolic Syndrome Warriors
If you're battling the frustrating combination of belly fat, blood sugar issues, and sluggish metabolism, SLU-PP-332 targets the exact pathways that go haywire in metabolic syndrome. It's like giving your metabolism a personal trainer that works 24/7.
Exercise-Limited Individuals
Injuries, disabilities, or conditions that prevent normal exercise don't have to mean giving up on metabolic health. SLU-PP-332 activates exercise pathways even when you can't hit the gym, potentially maintaining metabolic function during recovery periods.
Endurance Athletes Seeking an Edge
For those already training hard, SLU-PP-332 may amplify your body's natural adaptation to exercise. Research shows it synergizes with actual training, potentially helping you get more benefit from every workout.
Aging Adults Fighting Metabolic Decline
As we age, our mitochondria become less efficient and our metabolism slows. SLU-PP-332 targets the ERR receptors that control mitochondrial function, potentially helping maintain youthful metabolic capacity even as birthdays add up.
MOTS-c
Metabolic Health Optimizers
If you're looking to improve how your body handles glucose and energy, MOTS-c directly targets these systems. It's like giving your cells a metabolic tune-up, helping them respond better to insulin and process sugar more efficiently—key factors for long-term health.
Those Seeking Exercise-Like Benefits
Nicknamed an 'exercise mimetic,' MOTS-c activates many of the same pathways that get turned on during physical activity. While it's not a replacement for actual exercise, it may help enhance the benefits you get from working out or provide some metabolic support when exercise is limited.
Weight Management Seekers
Animal studies show impressive prevention of diet-induced obesity. While human data is still emerging, MOTS-c's effects on fat metabolism and insulin sensitivity suggest potential benefits for those working on healthy weight management alongside diet and exercise.
Healthy Aging Enthusiasts
MOTS-c levels naturally decline with age, which may contribute to age-related metabolic problems. Supplementing may help restore more youthful metabolic function, supporting the body's ability to regulate energy and maintain muscle mass as we get older.
Safety Profile
Side
effects
SLU-PP-332
Common
- Mild GI discomfort
- Increased energy
- Mild warmth or temperature increase
Uncommon
- Changes in appetite
- Mild headache
Serious
- Allergic reaction
MOTS-c
Common
- Injection site redness
- Mild fatigue
- Mild headache
Uncommon
- Changes in appetite
- Mild hypoglycemia symptoms
Serious
- Allergic reaction
Research Status
Safety
& evidence
SLU-PP-332
Evidence Level
Strong preclinical (extensive animal studies)
FDA Status
Research compound
Safety Overview
SLU-PP-332 has demonstrated a favorable safety profile in extensive preclinical studies. Mouse studies showed no severe adverse events even at relatively high doses, with researchers noting improvements in metabolic markers without negative effects on appetite, behavior, or organ function. The compound appears well-tolerated in animal models, though human clinical trials are still needed to fully establish its safety profile in people.
Contraindications
- xPregnancy or planning to become pregnant
- xCurrently breastfeeding
- xKnown allergy to the compound or similar chemicals
- xChildren and adolescents
- xSevere liver or kidney disease
MOTS-c
Evidence Level
Strong preclinical (extensive animal studies)
FDA Status
Research compound
Safety Overview
MOTS-c has shown an excellent safety profile in preclinical studies, with extensive animal research demonstrating beneficial effects without significant adverse events. The peptide is naturally produced by your own mitochondria, which suggests inherent compatibility with human biology. However, human clinical trial data is still limited, so caution is warranted. Most reported experiences involve minimal side effects, primarily mild injection site reactions.
Contraindications
- xPregnancy or planning to become pregnant
- xCurrently breastfeeding
- xActive cancer or history of cancer
- xKnown allergy to peptide components
- xChildren and adolescents
Decision Guide
Which is
right for you?
Choose SLU-PP-332 if...
- Enhanced metabolic health
- Fat loss without extreme dieting
- Improved exercise endurance
- Supporting mitochondrial function
Choose MOTS-c if...
- Metabolic health optimization
- Insulin sensitivity improvement
- Weight management support
- Mitochondrial function enhancement