Melanotan-2
MT-II, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Melanotan-2 (MT-II) is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) that acts as a non-selective melanocortin receptor agonist. Originally developed for skin pigmentation research, it has also been investigated for erectile dysfunction. NOT FDA approved and carries significant safety warnings from health agencies worldwide due to serious adverse effects including potential melanoma risk.
Complete Dosing Guide
Administration Guidelines
Injection Sites
- Abdomen: 2 inches away from navel (preferred site)
- Thigh: Front or outer thigh area
- Upper arm: Back of upper arm (triceps area)
- Choose areas with adequate subcutaneous fat
- Avoid areas with scars, bruises, moles, or skin irritation
Rotation Schedule
- Rotate injection sites with each dose
- Space injections at least 1 inch apart within same body region
- Keep injection log or mark calendar to track sites
- Prevents lipohypertrophy (fatty lumps under skin)
- Reduces tissue irritation and improves absorption
Timing
- For tanning: Evening injection 2-3 hours before bedtime or sun exposure
- For sexual enhancement: 2-4 hours before anticipated sexual activity
- For weight loss: Morning or midday between meals
- Consistent timing helps establish routine and optimize effects
- Evening dosing may help sleep through nausea side effects
Medical Disclaimer
CRITICAL WARNING: Melanotan-2 is NOT approved by the FDA or any major regulatory agency for human use. Health authorities worldwide have issued warnings against its use due to serious safety risks including potential melanoma, priapism, rhabdomyolysis, and systemic toxicity. This information is for educational and research purposes only. Any use requires medical supervision and carries significant legal and health risks. Consult healthcare providers for approved alternatives.