Kisspeptin
Kisspeptin-54 / Kisspeptin-10
Kisspeptin is a neuropeptide encoded by the KISS1 gene that plays a critical role in regulating the hypothalamic-pituitary-gonadal (HPG) axis. It stimulates gonadotropin-releasing hormone (GnRH) secretion by binding to the GPR54/Kiss1R receptor, making it essential for reproductive function, puberty onset, and fertility. Originally discovered as a metastasis suppressor in certain cancers, kisspeptin has emerged as a promising therapeutic target for reproductive disorders including infertility, hypothalamic amenorrhea, and hypoactive sexual desire disorder.
Complete Dosing Guide
Who Should Not Take Kisspeptin & Safety Tips
⚠️ Do Not Take If:
- You have active cancer (kisspeptin was originally discovered as a cancer metastasis suppressor)
- You're pregnant or breastfeeding (unless part of fertility treatment)
- You have uncontrolled endocrine disorders
⚠️ Use Carefully If:
- You have diabetes or metabolic syndrome
- You're taking other hormone therapies
- You have cardiovascular conditions
Medical Disclaimer
Kisspeptin is in Phase 2 clinical trials for reproductive applications. This information is for educational purposes only and should not be construed as medical advice. Any clinical use should occur only under medical supervision in approved research or clinical settings.