Kisspeptin
Kisspeptin-54 / Kisspeptin-10
Kisspeptin is a neuropeptide encoded by the KISS1 gene that plays a critical role in regulating the hypothalamic-pituitary-gonadal (HPG) axis. It stimulates gonadotropin-releasing hormone (GnRH) secretion by binding to the GPR54/Kiss1R receptor, making it essential for reproductive function, puberty onset, and fertility. Originally discovered as a metastasis suppressor in certain cancers, kisspeptin has emerged as a promising therapeutic target for reproductive disorders including infertility, hypothalamic amenorrhea, and hypoactive sexual desire disorder.
Complete Dosing Guide
Administration Guidelines
Injection Sites
- Subcutaneous injection preferred
- Alternate between abdomen, thigh, and upper arm
- Keep injection log to track sites
Rotation Schedule
- Rotate injection sites to prevent tissue irritation
- Use different areas each time
- Allow at least 1 inch between injection sites
Timing
- Inject at the same time of day for consistency
- Morning injections may align better with natural hormone rhythms
- Maintain 3-4 day minimum between doses
Medical Disclaimer
Kisspeptin is in Phase 2 clinical trials for reproductive applications. This information is for educational purposes only and should not be construed as medical advice. Any clinical use should occur only under medical supervision in approved research or clinical settings.