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Peptide Database

Adipotide
Weight Management
AOD-9604
Weight Management
BPC-157
Healing & Recovery
Cagrilintide
Weight Management
CJC-1295
Growth Hormone
DSIP
Sleep & Recovery
Epithalon
Anti-Aging
GHK-Cu
Anti-Aging
GHRP-2
Growth Hormone
HCG
Hormone Support
Hexarelin
Growth Hormone
HGH
Growth Hormone
IGF-1 LR3
Growth Hormone
Kisspeptin
Hormone Support
Melanotan-2
Cosmetic
MOTS-C
Metabolic
NAD+
Anti-Aging
Oxytocin Acetate
Hormone Support
PEG-MGF
Recovery
PNC-27
Cancer Research
PT-141
Sexual Health
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Snap-8
Cosmetic
SS-31
Mitochondrial
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Thymosin Alpha-1
Immune
Tirzepatide
Weight Management
Total Peptides: 32
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IGF-1 LR3

Long R3 Insulin-like Growth Factor-1

IGF-1 LR3 is a synthetic analog of human insulin-like growth factor 1, engineered with an arginine substitution at position 3 and 13 additional amino acids at the N-terminus. This 83-amino acid peptide exhibits reduced affinity for IGF-binding proteins, resulting in a prolonged half-life of 20-30 hours and approximately 3 times greater potency than native IGF-1. Currently investigational and not FDA-approved for human use.

Complete Dosing Guide

What is IGF-1 LR3?

IGF-1 LR3 (Insulin-Like Growth Factor-1 Long Arginine 3) is a synthetic analog of human insulin-like growth factor 1. It's an 83-amino acid peptide engineered with an arginine substitution at position 3 and 13 additional amino acids at the N-terminus. This modification gives IGF-1 LR3 reduced affinity for IGF-binding proteins, resulting in a significantly extended half-life of 20-30 hours compared to natural IGF-1's half-life of just 20-30 minutes. IGF-1 LR3 is approximately 3 times more potent than native IGF-1 and plays a crucial role in muscle growth, cellular repair, and metabolic function.

When is IGF-1 LR3 Used?

Muscle Growth & Development:

  • Promotes muscle hyperplasia (creation of new muscle cells).
  • Increases muscle cell size through hypertrophy.
  • Enhances protein synthesis and nutrient uptake into muscle tissue.
  • Activates satellite cells for muscle repair and growth.

Recovery & Tissue Repair:

  • Accelerates post-workout recovery and reduces muscle soreness.
  • Speeds healing of soft tissue injuries, tendons, and ligaments.
  • Supports joint health and reduces recovery time between training sessions.
  • Enhances overall tissue regeneration throughout the body.

Fat Loss & Body Composition:

  • Promotes fat metabolism while preserving lean muscle mass.
  • Improves nutrient partitioning for better body recomposition.
  • Increases metabolic rate and energy utilization.
  • Helps maintain muscle during caloric deficit.

Anti-Aging & Cellular Health:

  • Supports cellular regeneration and longevity.
  • Improves skin elasticity and collagen synthesis.
  • Enhances cognitive function and neuroprotection.
  • Promotes overall cellular health and repair processes.

Medical Disclaimer

IGF-1 LR3 is an investigational research compound not approved by the FDA for human therapeutic use. This information is provided for educational purposes only and should not be construed as medical advice. IGF-1 LR3 carries significant risks including severe hypoglycemia and potential tumor growth acceleration. Any use should only occur under strict medical supervision in approved research settings. Individuals with cancer history, diabetes, or other serious medical conditions should not use this compound.