
GHRP-2
Growth Hormone Releasing Peptide-2
GHRP-2 (Growth Hormone Releasing Peptide-2), also known as pralmorelin, is a synthetic hexapeptide that acts as a potent agonist at the ghrelin/growth hormone secretagogue receptor (GHS-R). It triggers pulsatile growth hormone release from the pituitary gland, mimicking the body's natural GH secretion patterns. GHRP-2 was developed as a diagnostic agent and is clinically approved in Japan for assessing growth hormone deficiency. Unlike direct GH administration, GHRP-2 works through the body's natural pathways, making it a preferred option for those seeking to enhance their natural growth hormone production safely and effectively.
Complete Dosing Guide
Patient Education
Helping you understand how to use GHRP-2 properly is key to your success. Here's what you need to know:
How to Inject GHRP-2 Correctly
Reconstitution Process:
- Add 1-2 mL bacteriostatic water to vial
- Direct water against vial wall, not directly on powder
- Gently swirl (do not shake) until dissolved
- Solution should be clear without particles
Injection Technique:
- Clean injection site with alcohol swab
- Use insulin syringe (29-31 gauge)
- Inject subcutaneously into abdomen, thigh, or deltoid
- Rotate injection sites to prevent lipodystrophy
- Inject slowly over 5-10 seconds
- Apply gentle pressure after removal
Dosage Calculation:
- If 5 mg vial reconstituted with 2 mL water
- Concentration = 2,500 mcg/mL
- For 100 mcg dose = 0.04 mL (4 units on insulin syringe)
Why It's Important to Stick to Your Schedule
Maintaining GH Pulses:
- Natural GH secretion is pulsatile
- Consistent timing mimics physiological patterns
- Irregular dosing reduces effectiveness
Avoiding Desensitization:
- Regular breaks prevent receptor downregulation
- Follow cycling protocols strictly
- Don't exceed recommended doses
Missed Dose Protocol:
- If within 2 hours of scheduled time: take as normal
- If more than 2 hours late: skip and resume next dose
- Never double dose to compensate
Understanding Side Effects and When to Get Help
Expected Effects:
- Increased hunger within 20-30 minutes
- Mild warmth or flushing post-injection
- Improved sleep quality within first week
Managing Common Side Effects:
- Water retention: Reduce sodium intake, stay hydrated
- Increased appetite: Plan meals accordingly, use for bulking advantage
- Tingling: Usually resolves within 2 weeks, reduce dose if severe
Seek Medical Attention If:
- Severe swelling or edema
- Persistent numbness or carpal tunnel symptoms
- Signs of allergic reaction
- Severe headaches or vision changes
- Unexplained fatigue or weakness
Making Lifestyle Changes to Boost Results
Nutrition Optimization:
- Time carbohydrates away from injections
- Increase protein intake to 1g/lb body weight
- Stay hydrated (minimum 3L water daily)
- Consider intermittent fasting with morning dose
Training Considerations:
- Implement progressive overload training
- Allow adequate recovery between sessions
- Post-workout dose enhances recovery
- Focus on compound movements
Sleep Hygiene:
- Maintain 7-9 hours nightly
- Consistent sleep schedule
- Dark, cool sleeping environment
- Bedtime dose enhances deep sleep
Supplement Support:
- Vitamin D3: 2000-5000 IU daily
- Magnesium: 400-800 mg before bed
- Zinc: 15-30 mg daily
- Omega-3 fatty acids: 2-3g daily
Keep Up with Doctor Visits
Initial Assessment:
- Baseline blood work including IGF-1
- Physical examination
- Review of medical history
- Discussion of goals and expectations
Follow-up Schedule:
- First follow-up: 4 weeks after starting
- Then every 8-12 weeks during treatment
- Blood work every 3 months
- Annual comprehensive evaluation
What to Track:
- Daily injection log
- Side effects diary
- Body composition changes
- Performance metrics
- Sleep quality scores
Medical Disclaimer
Clinical data presented is from peer-reviewed studies. Individual results may vary. Consult healthcare professionals before starting treatment. This information is for educational purposes only.