Epithalon
L-alanyl-L-glutamyl-L-aspartyl-glycine
Epithalon is a synthetic tetrapeptide consisting of four amino acids (Ala-Glu-Asp-Gly) developed by Khavinson and colleagues in Russia during the late 1980s. With a molecular weight of 390.35 g/mol, this compact peptide mimics a segment of the naturally occurring thymic peptide epithalamin extracted from pineal glands, making it a valuable tool for research into telomere elongation, pineal gland function, and cellular aging processes in controlled experimental settings.
Complete Dosing Guide
Patient Education
Helping you understand how to use Epithalon properly is key to your success. Here's what you need to know:
How to Reconstitute and Inject Epithalon Correctly
Before You Start:
- Check vial for damage or contamination
- Gather supplies: bacteriostatic water, alcohol wipes, syringes
- Calculate your daily dose based on total cycle amount
Steps to Reconstitute:
- Clean vial tops with alcohol wipe
- Add 1-2 mL bacteriostatic water to 10 mg vial
- Inject water slowly along vial wall
- Gently swirl - don't shake vigorously
- Let sit until fully dissolved
- Solution should be clear
Dosing Calculation:
- 10 mg in 2 mL = 5 mg/mL concentration
- For 1 mg dose, draw 0.2 mL
- For 0.5 mg dose, draw 0.1 mL
Injection Technique:
- Clean injection site with alcohol
- Pinch skin to create fold
- Insert needle at 45-90 degree angle
- Inject slowly and steadily
- Rotate sites with each injection
Why It's Important to Stick to Your Schedule
Cycle Adherence:
- Complete the full 10-20 day cycle
- Don't extend cycles beyond recommended duration
- Maintain consistent daily timing
Annual Planning:
- Schedule 2-3 cycles per year
- Mark calendar for next cycle
- Many use spring and fall timing
Missing Doses:
- If you miss a dose, take it as soon as remembered
- Don't double up on doses
- Continue with regular schedule
Understanding Side Effects and When to Get Help
Expected Initial Effects:
- May notice improved sleep within days
- Energy changes can occur in first week
- Skin improvements may take weeks to months
Monitoring Response:
- Keep a journal of improvements
- Note any unusual symptoms
- Track sleep quality and energy
When to Contact Provider:
- Any unexpected reactions
- Signs of infection at injection site
- Concerns about cancer risk
Making Lifestyle Changes to Boost Results
Sleep Optimization:
- Maintain consistent sleep schedule
- Create dark, cool sleeping environment
- Avoid screens before bedtime
- Epithalon enhances natural melatonin
Antioxidant Support:
- Eat colorful fruits and vegetables
- Consider vitamin C, E, and selenium
- Green tea and resveratrol may complement effects
Stress Management:
- Chronic stress accelerates aging
- Practice meditation or yoga
- Regular exercise supports longevity
Healthy Aging Practices:
- Maintain social connections
- Engage in mental stimulation
- Regular physical activity
- Mediterranean-style diet
Keep Up with Progress Tracking
Documentation:
- Photo documentation for skin changes
- Sleep diary to track improvements
- Energy and mood ratings
- Cognitive function observations
Cycle Evaluation:
- Assess benefits after each cycle
- Determine optimal frequency for you
- Adjust protocol based on response
Long-term Planning:
- Consider annual biomarker testing
- Maintain relationship with healthcare provider
- Stay informed about longevity research
Combination Strategies:
- May combine with other peptides
- Coordinate with supplement regimen
- Integrate with overall wellness plan
Medical Disclaimer
Epithalon is an investigational research compound not approved by the FDA for human therapeutic use. This information is for educational purposes only and should not be construed as medical advice. Long-term safety data in humans is extremely limited.