DSIP
L-tryptophyl-L-alanyl-glycyl-glycyl-L-aspartyl-L-alanyl-L-seryl-glycyl-L-glutamic acid
DSIP is a naturally occurring nonapeptide identified in 1977 from rabbit cerebral venous blood, comprising nine amino acids in the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. This linear, hydrophilic peptide maintains its endogenous structure without synthetic modifications, making it ideal for sleep regulation research, stress response modulation, and central nervous system function studies in controlled experimental settings.
Complete Dosing Guide
Patient Education
How to Inject DSIP Correctly
Preparation:
- Allow vial to reach room temperature before use
- Check solution clarity - should be clear without particles
- Gather supplies: alcohol swabs, sterile syringe, sharps container
Injection Steps:
- Wash hands thoroughly with soap and water
- Clean injection site with alcohol swab and let dry
- Draw prescribed dose into syringe
- Pinch skin at injection site (abdomen, thigh, or upper arm)
- Insert needle at 45-90 degree angle
- Inject slowly and steadily
- Remove needle and apply gentle pressure
- Dispose of needle in sharps container
Injection Site Rotation:
- Rotate sites with each injection
- Keep sites at least 1 inch apart
- Avoid areas with scars, bruises, or irritation
Why It's Important to Stick to Your Schedule
Timing Consistency:
- Take at the same time relative to bedtime
- Maintains stable peptide levels
- Optimizes sleep architecture
Avoiding Tolerance:
- Follow recommended cycling protocols
- Don't increase dose without guidance
- Take scheduled breaks as advised
Missed Dose:
- If less than 3 hours until bedtime: take as normal
- If less than 3 hours: skip and resume next scheduled dose
- Never double dose to make up for missed injection
Understanding Side Effects and When to Get Help
Expected Effects:
- Feeling of "sleep pressure" within 2 hours
- Improved sleep without classic sedation
- Possible mild headache initially
Managing Side Effects:
- Headaches usually resolve within first few doses
- Take earlier if experiencing morning grogginess
- Reduce dose if excessive daytime sleepiness occurs
Seek Medical Attention If:
- Severe drop in blood pressure (dizziness, fainting)
- Allergic reaction (rash, swelling, difficulty breathing)
- Prolonged drowsiness lasting more than 24 hours
- Any concerning neurological symptoms
Making Lifestyle Changes to Boost Results
Sleep Hygiene:
- Maintain consistent sleep-wake schedule
- Create dark, cool sleeping environment
- Avoid screens 1-2 hours before bed
- Limit caffeine after 2 PM
Stress Management:
- Practice relaxation techniques
- Consider meditation or yoga
- Regular moderate exercise (not close to bedtime)
- Manage work-life balance
Dietary Considerations:
- Avoid heavy meals 3 hours before bed
- Limit alcohol consumption
- Stay hydrated throughout the day
- Consider magnesium supplementation
Behavioral Support:
- Keep a sleep diary to track progress
- Consider cognitive behavioral therapy for insomnia (CBT-I)
- Join support groups if using for withdrawal
Keep Up with Doctor Visits
Initial Phase:
- Weekly check-ins during first month
- Blood pressure monitoring
- Sleep quality assessments
Maintenance Phase:
- Monthly follow-ups
- Periodic evaluation of continued need
- Dose adjustments as needed
Documentation:
- Keep detailed logs of sleep patterns
- Record any side effects
- Note changes in other symptoms
Medical Disclaimer
DSIP is an investigational research compound not approved by the FDA for human therapeutic use. This information is for educational purposes only and should not be construed as medical advice. Any use should occur only under medical supervision in approved research settings.