Selank
N-[(3S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]propanoyl]pyrrolidin-2-yl]formyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]-1H-imidazole-4-carboxamide
Selank is a synthetic anxiolytic peptide that selectively modulates GABA and serotonin neurotransmitter systems while enhancing BDNF expression. It provides anxiolytic effects without sedation, making it ideal for cognitive enhancement and stress management applications.
Complete Research Database
Dual Receptor Mechanism (GIP/GLP-1)
GLP-1 Receptor Pathway
- •Increases insulin secretion (glucose-dependent)
- •Suppresses glucagon release
- •Slows gastric emptying
- •Enhances satiety in hypothalamus
- •Preserves beta-cell function
GIP Receptor Pathway
- •Enhances insulin secretion (stronger than GLP-1)
- •Promotes fat oxidation
- •Improves insulin sensitivity in muscle
- •Reduces hepatic glucose production
- •Modulates adipose tissue metabolism
Why Dual Agonism is Superior
Selank selectively enhances GABAergic neurotransmission and modulates serotonin pathways through direct receptor interaction and indirect BDNF upregulation. It influences neurotransmitter synthesis and release while promoting neuroplasticity through brain-derived neurotrophic factor expression, resulting in anxiolytic effects without cognitive impairment or sedation.
Pharmacokinetic Profile
Top 10 High-Quality Research Articles
Medical Disclaimer
This information is for educational purposes only and is not intended as medical advice. Selank is a research compound and should only be used under qualified medical supervision. Consult with a healthcare provider familiar with peptide therapies before considering use. Individual results may vary significantly.